The Role of Spousal Biobehavioral Co-regulation in Everyday Collaborative Memory: Identifying Targets for Intervention

配偶生物行为共同调节在日常协作记忆中的作用：确定干预目标

• 批准号: 10605169
• 负责人: CELINDA REESE MELANCON
• 金额: $ 58.94万
• 依托单位: IOWA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10605169
• 关键词: Address; Adult; Affect; Age; Autonomic nervous system; Behavior; Behavior Therapy; Behavioral; Belief; Biological Markers; Characteristics; Clinical; Cognitive; Cognitive aging; Collaborations; Compensation; Complex; Couples; Data; Dementia; Development; Diagnosis; Ecological momentary assessment; Elderly; Emotions; Environment; Exhibits; Failure; Future; Goals; Health; Home; Hydrocortisone; Independent Living; Individual; Influentials; Intervention; Investigation; Knowledge; Laboratories; Life; Measurement; Measures; Memory; Outcome; Pathway interactions; Perception; Performance; Persons; Pharmaceutical Preparations; Physiological; Physiological Processes; Play; Process; Research; Research Personnel; Resources; Retrieval; Role; Safety; Salivary; Social Processes; Source; Spouses; Stress; System; Testing; Work; aging in place; behavioral response; biobehavior; biological adaptation to stress; clinical practice; cognitive ability; cognitive change; cognitive development; cognitive performance; cognitive process; cognitive task; experience; hypothalamic-pituitary-adrenal axis; indexing; innovation; member; middle age; mild cognitive impairment; prospective memory; resilience; skills; social; success; therapy development; tutoring

Project Summary/Abstract Significant work demonstrates the influence of spouses on one another’s emotions, behaviors, and health- related outcomes. What is not understood is the role partners play in cognitive development, change, and adaptation in middle and later life. Because researchers have not identified the biobehavioral mechanisms and processes that couples employ as they navigate normative and non-normative (i.e., mild cognitive impairment, dementia) cognitive aging, development of effective behavioral interventions to maintain and bolster performance is impeded. Prospective memory (PM), or memory for future actions, is essential to health and safety (e.g., remembering to take medication or turn off a stove) and ultimately, the ability to age in place. To remain in their homes, older adults must maintain this critical memory skill. The proposed research will identify behaviors of middle-aged and older adults when they collaborate on PM tasks and determine how those behaviors and the accompanying stress response affect PM. The central hypothesis underlying this research is that significant others are inherently involved in daily memory tasks and exert substantial “partner” effects, which positively (e.g., compensation) and/or negatively (e.g., retrieval interference, increased stress) influence PM outcomes. To test the hypothesis, this research addresses four specific aims: 1) Determine the effects of individual and dyadic characteristics on collaborative PM performance in laboratory and real-world contexts, 2) Investigate social and cognitive behaviors exhibited during the collaborative process to determine the impact of dyadic behaviors on PM performance, 3) Identify the concomitant effects of partners’ stress responses and ability on collaborative PM performance, and 4) Investigate biobehavioral processes and corresponding performance within a clinical subsample of dyads for whom one partner has MCI or early-stage dementia. The research is significant because it systematically examines the commonplace (but unstudied) phenomenon of partner interactions to identify the socio-cognitive and physiological processes important to PM and how these biobehavioral pathways may differ for couples experiencing non-normative cognitive change. The work is innovative because it includes measurement of dyadic attunement and incorporates investigation of spouses who experience cognitive change at different rates and thus are faced with the need to compensate for a partner who is struggling with the cognitive tasks of daily life. The proposed research is essential to achieving our goal of developing behaviorally-based interventions to enhance critical everyday memory behaviors and promote independent living.

项目总结/摘要 重要的工作表明配偶对彼此的情绪，行为和健康的影响- 相关成果。不了解的是伴侣在认知发展、变化和 适应中晚期生活。因为研究人员还没有确定生物行为机制， 夫妇在他们驾驭规范和非规范时采用的过程（即，轻度认知障碍， 痴呆）认知老化，发展有效的行为干预，以维持和支持 业绩受阻。前瞻性记忆（PM），或对未来行动的记忆，对健康和 安全性（例如，记得吃药或关掉炉子），最终，在原地变老的能力。到 当老年人呆在家里时，他们必须保持这种重要的记忆技能。拟议的研究将确定 行为的中年和老年人时，他们合作的PM任务，并确定如何这些 行为和伴随的压力反应影响PM。这项研究的核心假设是 重要的其他人天生就参与日常记忆任务，并发挥实质性的“伙伴”效应， 其积极地（例如，补偿）和/或负面地（例如，检索干扰，增加压力）影响 PM结果。为了验证这一假设，本研究提出了四个具体目标：1）确定 在实验室和现实世界的背景下，合作PM性能的个人和二元特征，2） 调查协作过程中表现出的社会和认知行为，以确定 二元行为对项目管理绩效的影响，3）识别合作伙伴压力反应的伴随效应， 合作PM性能的能力，以及4）调查生物行为过程和相应的 在一个伴侣患有MCI或早期痴呆的二人临床子样本中的表现。的 研究是重要的，因为它系统地研究了常见的（但未经研究的）现象， 合作伙伴的互动，以确定社会认知和生理过程的重要性PM，以及如何这些 生物行为途径对于经历非规范性认知变化的夫妇可能不同。这项工作是 创新，因为它包括测量二元协调，并纳入配偶的调查 他们以不同的速度经历认知变化，因此面临着补偿 在日常生活的认知任务中苦苦挣扎的伴侣。拟议的研究对实现 我们的目标是开发基于行为的干预措施，以增强关键的日常记忆行为， 促进独立生活。