3rd International Symposium on the Exstrophy - Epispadias Complex

第三届外翻国际研讨会 - Epispadias Complex

• 批准号: 7750273
• 负责人: JOHN P GEARHART
• 金额: $ 1.15万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-14 至 2010-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7750273
• 关键词: Area; Bladder Exstrophy; Child; Collaborations; Complex; Development; Epispadias; Etiology; Family; Fertility; Genital system; Incontinence; Individual; International; Kidney; Lead; Learning; Life; Medical; Nature; Outcome; Physiology; Publications; Research; Research Personnel; Staging; Surgical Management; Variant; Work; improved; malformation; reconstruction; success; symposium

DESCRIPTION (provided by applicant): Bladder exstrophy, cloacal exstrophy, and epispadias are all variants of the exstrophyepispadias complex. Although this is an uncommon congenital anomaly, its effects on the child and family are life-long. Over the last 50 years, slow, incremental refinements in the medical and surgical management of these conditions have permitted most children to lead productive lives with good renal outcomes. Yet, while significant gains have been made, the etiology for the development of the complex and the mechanisms that do not permit complete success in all children still remain to be determined. There is still much to be learned in areas of such as incontinence management, detrusor physiology, genital reconstruction, and fertility as they relate to exstrophy, epispadias, and cloacal exstrophy. This symposium intends to concentrate on those areas. The 3rd International Symposium on the Exstrophy - Epispadias Complex is the only academic forum dedicated solely to the exchange of ideas in the management of these conditions and again brings together recognized international experts in the field and allows for their cross talk with junior investigators and young clinicians, setting the stage for continued advancement. Fifteen to twenty minute talks will be presented by individuals with considerable expertise in the field of exstrophy and epispadias. These sessions will then be followed by open panel discussions in which audience participation is permitted. Fielding a panel of speakers with diverse views on the various aspects of research and management will permit a vigorous exchange of ideas. There will also be opportunities for young researchers in the field to present their continuing work. Presenters will have their material submitted for publication in the conference proceedings. Our two previous symposiums were well attended and reviews were universally positive. It is hoped that the continued rapport generated by conferences of this nature will permit greater collaboration between researchers in the field from all parts of the world and further improve our understanding of this complex set of malformations. While bladder exstrophy, epispadias, and cloacal exstrophy doomed children to dismal outcomes fifty years ago, slow, incremental refinements in the medical and surgical management of these conditions have permitted most children to lead productive lives with good renal outcomes. Yet, while significant gains have been made, the etiology for the development of the complex and the mechanisms that do not permit complete success in all children still remain to be determined. The 3rd International Symposium on the Exstrophy - Epispadias Complex is the only academic forum dedicated solely to the exchange of ideas in the management of these conditions and brings together recognized international experts in the field and allows for their cross talk with junior investigators and young clinicians, setting the stage for continued advancement.

描述（由申请人提供）：膀胱外翻、泄殖腔外翻和尿道上裂都是尿道外裂复合体的变体。虽然这是一种罕见的先天性异常，但其对儿童和家庭的影响是终身的。在过去的50年里，这些疾病的医疗和手术管理的缓慢，渐进的改进使大多数儿童能够过上富有成效的生活，并获得良好的肾脏结果。然而，虽然已经取得了重大进展，复杂的发展和机制，不允许在所有儿童完全成功的病因仍然有待确定。在失禁管理、逼尿肌生理学、生殖器重建和生育等领域仍有许多需要学习的，因为它们与外翻、尿道上裂和泄殖腔外翻有关。本次专题讨论会打算集中讨论这些领域。 第三届外翻- Epispadias Complex国际研讨会是唯一一个专门致力于这些条件管理的学术论坛，并再次汇集了该领域公认的国际专家，并允许他们与初级研究人员和年轻的临床医生进行交流，为继续发展奠定基础。十五至二十分钟的会谈将提出由个人在exstrophy和epispadias领域的相当专业知识。这些会议之后将举行公开小组讨论，允许听众参加。派出一个对研究和管理的各个方面有不同看法的发言者小组，将使人们能够积极地交换意见。该领域的年轻研究人员也将有机会介绍他们的持续工作。演讲者将提交他们的材料，以便在会议记录中发表。我们前两次的研讨会都有很多人参加，评价也普遍是积极的。希望这种性质的会议所产生的持续的融洽关系将允许来自世界各地的该领域的研究人员之间进行更大的合作，并进一步提高我们对这一复杂畸形的理解。 50年前，膀胱外翻、尿道上裂和泄殖腔外翻注定了儿童的悲惨结局，而这些疾病的医疗和手术治疗的缓慢、渐进的改进使大多数儿童能够过上富有成效的生活，并获得良好的肾脏结局。然而，虽然已经取得了重大进展，复杂的发展和机制，不允许在所有儿童完全成功的病因仍然有待确定。第三届外翻- Epispadias Complex国际研讨会是唯一一个专门致力于这些条件管理的学术论坛，汇集了该领域公认的国际专家，并允许他们与初级研究人员和年轻的临床医生进行交流，为继续发展奠定基础。