12th Biennial Graylyn Conference on Women's Cognitive Health

第十二届两年一度的格雷林妇女认知健康会议

• 批准号: 7806199
• 负责人: Sally Ann SHUMAKER
• 金额: $ 4.5万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7806199
• 关键词: Address; Animals; Area; Basic Science; Behavioral; Centers of Research Excellence; Clinical; Clinical Research; Cognitive; Cognitive aging; Communities; Community Outreach; Complex; Dementia; Discipline; Economics; Education; Evidence Based Medicine; Family; Goals; Health; Health Sciences; Health Services; Health Services Research; Hormonal; Human; Impaired cognition; Individual; Knowledge; Lead; Leadership; Memory; Molecular; Policies; Research; Research Personnel; Scientist; Social Impacts; Symptoms; Translational Research; Universities; Woman; Women' s Health; age related; age related cognitive change; bench to bedside; design; disorder prevention; economic impact; forest; hormone therapy; improved; innovation; meetings; novel strategies; prevent; public health relevance; social; symposium; therapy design

DESCRIPTION (provided by applicant): The treatment and prevention of diseases that are unique to women is a critical area of research that encompasses the entire spectrum of approaches from molecular to social, behavioral and economic endpoints. This breadth of scientific endeavors is being used to determine the age-related cognitive changes that occur in women and to identify the most effective approaches to prevent cognitive decline in women. Interactions among disciplines and between basic, clinical and health services scientists will lead to the most efficacious translational interventions designed to enhance cognitive health. The Women's Health Center of Excellence for Research, Leadership, Education (WHCoE) of the Wake Forest University Health Sciences (WFUHS) began annual Graylyn Conferences of Women's Health in 1995 and in 1997 established the biennial Graylyn Conferences on Women's Cognitive Health for cutting-edge cognitive research related to women's health. The 2007 Graylyn Conference on Women's Cognitive Health explored issues specific to hormone therapy (HT) and broader issues related to women's cognitive aging. Since that meeting, clinical and basic science research has continued the goal of better understanding the results obtained in the Women's Health Initiative Memory Study (WHIMS) and the Women's Health Initiative Study of Cognitive Aging (WHISCA) and more fully exploring novel approaches designed to address the broader complex questions of age-related cognitive dysfunction in women. We plan to continue this critical and evolving dialogue among leaders in the field of women's cognitive health through the12th Graylyn Conference to be held in 2009 entitled "Improving the Trajectory of Cognitive Aging in Women through Innovative Translational Research". Invited speakers will present and critically review the current knowledge from basic to clinical research and health services research in order to guide efforts toward developing an innovative research agenda about hormonal and other therapies relevant to the advancement of knowledge in women's cognitive aging. As in the past, this conference will be relatively small (about 100 attendees) with speakers providing cutting-edge scientific presentations in themed areas. The emphasis of conference sessions will be on research from bench to bedside to community policy and practice with a translational focus. Discussions will be on how to enhance translational dialogues that include multiple disciplines, and on identifying the key directions for research on women's cognitive aging at the molecular, animal, human studies, and community outreach and practice of evidence-based medicine levels. PUBLIC HEALTH RELEVANCE: Among women, cognitive aging is a critical concern that has social impact on the individual, her family, as well as an enormous economic impact. Enhancing our understanding of the problems associated with cognitive aging would assist in addressing this growing concern. This conference enables investigators from various disciplines worldwide to tackle the problem by developing new mechanisms to detect cognitive decline and develop promising treatments that may delay the onset and progression of the symptoms associated with dementia.

描述（由申请人提供）：治疗和预防妇女特有的疾病是一个关键的研究领域，包括从分子到社会，行为和经济终点的整个方法。这种广泛的科学努力正在被用来确定与年龄有关的认知变化，发生在妇女和确定最有效的方法，以防止认知能力下降的妇女。学科之间以及基础、临床和卫生服务科学家之间的相互作用将导致旨在增强认知健康的最有效的转化干预措施。维克森林大学健康科学（WFUHS）的妇女健康卓越研究、领导和教育中心（WHCoE）于1995年开始举办年度格雷林妇女健康会议，并于1997年建立了两年一度的格雷林妇女认知健康会议，以进行与妇女健康有关的尖端认知研究。2007年Graylyn妇女认知健康会议探讨了激素治疗（HT）的具体问题和与妇女认知老化有关的更广泛的问题。自那次会议以来，临床和基础科学研究继续更好地理解妇女健康倡议记忆研究（WHIMS）和妇女健康倡议认知老化研究（WHISCA）中获得的结果，并更充分地探索旨在解决更广泛的复杂问题的新方法。我们计划通过将于2009年举行的题为“通过创新转化研究改善妇女认知老化轨迹”的第12届Graylyn会议，继续在妇女认知健康领域的领导人之间开展这一重要和不断发展的对话。特邀演讲者将介绍并批判性地回顾从基础到临床研究和卫生服务研究的现有知识，以指导努力制定有关激素和其他疗法的创新研究议程，以促进妇女认知老化的知识。与过去一样，本次会议将相对较小（约100名与会者），演讲者将在主题领域提供尖端的科学演讲。会议的重点将是从板凳到床边的社区政策和实践的研究与翻译的重点。将讨论如何加强包括多个学科的翻译对话，并确定在分子，动物，人类研究以及循证医学水平的社区推广和实践方面研究女性认知老化的关键方向。 公共卫生关系：在妇女中，认知老化是一个严重的问题，对个人、家庭产生社会影响，并产生巨大的经济影响。提高我们对认知老化相关问题的理解将有助于解决这一日益严重的问题。这次会议使来自世界各地不同学科的研究人员能够通过开发新的机制来解决这个问题，以检测认知能力下降，并开发有希望的治疗方法，这些治疗方法可能会延迟痴呆症相关症状的发作和进展。