2009 Plant Metabolic Engineering Gordon Research Conference

2009植物代谢工程戈登研究会议

• 批准号: 7673030
• 负责人: Joe Chappell
• 金额: $ 0.4万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7673030
• 关键词: Academia; Anabolism; Applied Research; Biochemical Pathway; Biological; Biological Factors; Chemicals; Chemistry; Communities; Development; Disabled Persons; Doctor of Philosophy; Drug usage; Engineering; Environment; Food Supply; Genomics; Goals; Health Food; Human; Individual; Industry; Institutes; Institution; Interdisciplinary Study; Joints; Laboratories; Lead; Learning; Mediating; Metabolic; Metabolism; New Hampshire; Nutritional; Ownership; Participant; Pathway interactions; Persons; Pharmaceutical Preparations; Plants; Postdoctoral Fellow; Production; Research; Role; Scientist; Series; Source; Students; Therapeutic; Time; Woman; career; design; drug development; meetings; novel; nutrition; peer; public health relevance; symposium

DESCRIPTION (provided by applicant): More than 200,000 individual chemical entities or Natural Products from plants have been identified. Given the multiplicity of chiral centers, elaboration with modifying substituents and the important roles these compounds mediate between plants and the environment, plant natural products have served well in the design and development of approximately two-thirds of all the drugs used by mankind. The post-genomic era now presents new opportunities for manipulating plant chemistry that will further impact the level and nutritional content of the global food supply and lead to new biological sources of novel drugs and therapeutic compounds. To provide a setting for the development of the multidisciplinary collaborations needed to unravel the complexity of plant natural product biosynthesis and the dynamics of metabolic networks, and to advance basic and applied research in plant metabolic engineering in support of drug development activities, we are requesting support for the 2009 Gordon Research Conference (GRC) and joint Graduate Research Seminar (GRS) on Plant Metabolic Engineering to be held July 11-17, 2009 at the Waterville Valley conference center in New Hampshire. Similar to the first 2 meetings of this new conference series, we expect the number of speakers and participants to reach upwards of 175 persons from the US and abroad, at all career levels, and representing institutions from academia, industry, private institutes, and federal laboratories. Concerted efforts will continue to encourage the participation of women, persons with disabilities, and scientists from underrepresented groups. As was done for the first time in 2007, we will also host a Graduate Research Seminar (GRS) immediately prior to the GRC. Our first GRS' provided a unique venue for junior scientists (Ph.D. students and postdoctoral fellows) to present their research results in a setting of their direct peers, to learn how to evolve new research ideas and notions amongst a diverse audience, and helped to build a much more dynamic and interactive scientific community because the GRS participants were fully integrated into the larger GRC meeting as well. The 2009 GRS will be centered on "Roundtable Discussions" and opportunities for participants to openly discuss issues related to the field in general, thus providing the participants with an opportunity to establish ownership of a field, a community and a meeting venue. All participants to the GRS are expected to stay for the GRC, further enhancing the educational component of this conference. Public Health Relevance: Project Narrative the GRC in Plant Metabolic Engineering provides a setting for developing the multidisciplinary collaborations and interactions needed to unravel the dynamic complexity of plant metabolism with the purpose of manipulating pathways towards the goal of altering the levels of metabolites with importance to human health, food nutrition, energy production and agronomic production of plants.

描述（由申请人提供）：已鉴定出200，000多种来自植物的化学实体或天然产物。鉴于手性中心的多样性，修饰取代基的修饰以及这些化合物在植物和环境之间介导的重要作用，植物天然产物在人类使用的所有药物的约三分之二的设计和开发中发挥了很好的作用。后基因组时代现在为操纵植物化学提供了新的机会，这将进一步影响全球食品供应的水平和营养含量，并导致新药和治疗化合物的新生物来源。为发展多学科合作提供一个环境，以揭示植物天然产物生物合成的复杂性和代谢网络的动态，并推进植物代谢工程的基础和应用研究，以支持药物开发活动，我们请求支持2009年戈登研究会议（GRC）和联合研究生研究研讨会（GRS）将于2009年7月11日至17日在新罕布什尔州的沃特维尔山谷会议中心举行。与这个新会议系列的前两次会议类似，我们预计演讲者和参与者的数量将达到175人以上，来自美国和国外，在所有职业水平，并代表来自学术界，工业界，私营机构和联邦实验室的机构。协调一致的努力将继续鼓励妇女、残疾人和代表性不足群体的科学家参与。正如2007年第一次所做的那样，我们还将在GRC之前举办研究生研究研讨会（GRS）。我们的第一个GRS'为初级科学家（博士）提供了一个独特的场所。研究生和博士后研究员）在直接同行的环境中展示他们的研究成果，学习如何在不同的观众中发展新的研究思路和概念，并帮助建立一个更具活力和互动性的科学界，因为GRS的参与者也完全融入了更大的GRC会议。2009年全球报告系统将以“圆桌讨论会”为中心，并为与会者提供机会，公开讨论与该领域有关的一般问题，从而为与会者提供机会，确立对一个领域、一个社区和一个会议地点的所有权。预计所有参加GRS的人都将参加GRC，进一步加强本次会议的教育部分。 公共卫生相关性：植物代谢工程中的GRC为开发多学科合作和相互作用提供了一个环境，这些合作和相互作用需要解开植物代谢的动态复杂性，目的是操纵途径，以改变对人类健康，食品营养，能源生产和植物农艺生产具有重要意义的代谢物水平。