2009 Plant Metabolic Engineering Gordon Research Conference

2009植物代谢工程戈登研究会议

• 批准号: 7673030
• 负责人: Joe Chappell
• 金额: $ 0.4万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7673030
• 关键词: Academia; Anabolism; Applied Research; Biochemical Pathway; Biological; Biological Factors; Chemicals; Chemistry; Communities; Development; Disabled Persons; Doctor of Philosophy; Drug usage; Engineering; Environment; Food Supply; Genomics; Goals; Health Food; Human; Individual; Industry; Institutes; Institution; Interdisciplinary Study; Joints; Laboratories; Lead; Learning; Mediating; Metabolic; Metabolism; New Hampshire; Nutritional; Ownership; Participant; Pathway interactions; Persons; Pharmaceutical Preparations; Plants; Postdoctoral Fellow; Production; Research; Role; Scientist; Series; Source; Students; Therapeutic; Time; Woman; career; design; drug development; meetings; novel; nutrition; peer; public health relevance; symposium

DESCRIPTION (provided by applicant): More than 200,000 individual chemical entities or Natural Products from plants have been identified. Given the multiplicity of chiral centers, elaboration with modifying substituents and the important roles these compounds mediate between plants and the environment, plant natural products have served well in the design and development of approximately two-thirds of all the drugs used by mankind. The post-genomic era now presents new opportunities for manipulating plant chemistry that will further impact the level and nutritional content of the global food supply and lead to new biological sources of novel drugs and therapeutic compounds. To provide a setting for the development of the multidisciplinary collaborations needed to unravel the complexity of plant natural product biosynthesis and the dynamics of metabolic networks, and to advance basic and applied research in plant metabolic engineering in support of drug development activities, we are requesting support for the 2009 Gordon Research Conference (GRC) and joint Graduate Research Seminar (GRS) on Plant Metabolic Engineering to be held July 11-17, 2009 at the Waterville Valley conference center in New Hampshire. Similar to the first 2 meetings of this new conference series, we expect the number of speakers and participants to reach upwards of 175 persons from the US and abroad, at all career levels, and representing institutions from academia, industry, private institutes, and federal laboratories. Concerted efforts will continue to encourage the participation of women, persons with disabilities, and scientists from underrepresented groups. As was done for the first time in 2007, we will also host a Graduate Research Seminar (GRS) immediately prior to the GRC. Our first GRS' provided a unique venue for junior scientists (Ph.D. students and postdoctoral fellows) to present their research results in a setting of their direct peers, to learn how to evolve new research ideas and notions amongst a diverse audience, and helped to build a much more dynamic and interactive scientific community because the GRS participants were fully integrated into the larger GRC meeting as well. The 2009 GRS will be centered on "Roundtable Discussions" and opportunities for participants to openly discuss issues related to the field in general, thus providing the participants with an opportunity to establish ownership of a field, a community and a meeting venue. All participants to the GRS are expected to stay for the GRC, further enhancing the educational component of this conference. Public Health Relevance: Project Narrative the GRC in Plant Metabolic Engineering provides a setting for developing the multidisciplinary collaborations and interactions needed to unravel the dynamic complexity of plant metabolism with the purpose of manipulating pathways towards the goal of altering the levels of metabolites with importance to human health, food nutrition, energy production and agronomic production of plants.

描述（由申请人提供）：已经确定了200,000多个工厂的化学实体或天然产品。鉴于手性中心的多样性，用修饰的取代基的详细说明以及这些化合物在植物和环境之间介导的重要作用，植物天然产物在人类使用的所有药物中约有三分之二的植物天然产物中都很好地服务。现在的基因组时代为操纵植物化学提供了新的机会，这将进一步影响全球粮食供应的水平和营养含量，并导致新型药物和治疗化合物的新生物学来源。 To provide a setting for the development of the multidisciplinary collaborations needed to unravel the complexity of plant natural product biosynthesis and the dynamics of metabolic networks, and to advance basic and applied research in plant metabolic engineering in support of drug development activities, we are requesting support for the 2009 Gordon Research Conference (GRC) and joint Graduate Research Seminar (GRS) on Plant Metabolic Engineering to be held July 11-17, 2009 at the Waterville新罕布什尔州的山谷会议中心。与这个新会议系列的前两次会议类似，我们期望演讲者和参与者的人数能够达到美国和国外的175人，在所有职业级别上，并代表来自学术界，工业，私人机构和联邦实验室的机构。一致的努力将继续鼓励妇女，残疾人和代表性不足的群体的科学家的参与。正如2007年第一次这样做一样，我们还将在GRC之前立即举办研究生研究研讨会（GRS）。我们的第一个GRS为初级科学家（博士学位和博士后研究员）提供了一个独特的场所，以在他们的直接同龄人的环境中呈现他们的研究结果，以学习如何在多样化的受众中发展新的研究思想和概念，并帮助建立了更具动态性和互动性的科学社区，因为GRS参与者完全融入了更大的GRC会议，并融入了更大的GRC会议。 2009年的GRS将集中在“圆桌讨论”和参与者的机会上，有机会公开讨论与该领域有关的问题，从而为参与者提供了建立领域，社区和会议场所的所有权的机会。预计GRS的所有参与者都将留在GRC中，进一步增强了本次会议的教育部分。 公共卫生相关性：项目叙事植物代谢工程中的GRC为开发植物代谢的动态复杂性所需的多学科合作和相互作用提供了一种设置，目的是操纵途径，以操纵途径，以改变对人类健康，食物营养，食品营养，农产品生产的重要性，以改变代谢物的水平。