Conference on Molecular Biology of Hearing and Deafness

听力与耳聋分子生物学会议

• 批准号: 7675188
• 负责人: Allen F. Ryan
• 金额: $ 2.97万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-03-01 至 2010-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7675188
• 关键词: Address; Area; Auditory; Auditory system; Boston; Cells; Collaborations; Complex; Development; Diagnostic; Disease; Education; Epigenetic Process; Etiology; Family; Genes; Genetic; Genetic Screening; Hair Cells; Hearing; Hearing problem; Heterogeneity; Inherited; Laboratories; Labyrinth; Lead; Maps; Minority; Molecular; Molecular Biology; Molecular Evolution; Molecular Genetics; Mutation; Natural regeneration; Participant; Phenotype; Regulation; Research; Scholarship; Schools; Scientist; Therapeutic; Tissues; Translational Research; Travel; Visual system structure; base; cellular transduction; cost; deafness; gene function; gene therapy; outreach; patient advocacy group; profilin; repaired; symposium

DESCRIPTION (provided by applicant): Partial support is requested to host the 7th Conference on the Molecular Biology of Hearing and Deafness. The conference will be held in Boston, MA in June, 2009. The aims of the conference are to: 1) promote research in emerging areas of molecular biology that have not been extensively applied to the auditory system; 2) review progress in molecular biology related to hearing and deafness; 3) facilitate interaction and collaboration between different laboratories engaged in molecular auditory research, as well as between basic scientists and clinicians; 4) encourage translational research that can lead to diagnostics and therapeutics for the treatment of hearing disorders; and 5) provide outreach to patient advocacy groups and schools in the Boston area, with education on the genetics of deafness and hearing research. Speakers from outside of the auditory system will address applications of high-throughput sequencing, computational genetics and the HapMap project, molecular evolution and disease mapping, recent advances in molecular biology of the visual system, as well as additional topics. Auditory sessions will include, but are not limited to: molecular genetics; epigenetic mechanisms; development; integrated gene function; the molecular basis of hearing and vestibular disorders; genetic screening and gene therapy; and regeneration. Support is requested to offer scholarships for minority attendees and trainees, defray the travel costs of some invited participants, and support other costs associated with hosting the conference. Project Narrative: Partial support is requested to host the 7th Conference on the Molecular Biology of Hearing and Deafness. The Conference will be held in Boston, MA in June, 2009. Topics of the Conference include, but are not limited to: molecular genetics and gene mapping of inherited deafness; mutational heterogeneity and deafness phenotypes; families of functionally related deafness genes; complex genetics in inherited deafness; molecular regulation of auditory development; genetics of cell phenotype in the inner ear; molecular basis of hair cell transduction; central auditory system; auditory tissue specific gene activity and expression profilin; cochlear damage, regeneration and repair; molecular diagnostics of deafness mutations; molecular biology of otologic disease: etiology and therapy.

描述（由申请人提供）：部分支持，要求主办第七届会议的听力和耳聋的分子生物学。会议将于2009年6月在马萨诸塞州波士顿举行。会议的目的是：1）促进尚未广泛应用于听觉系统的分子生物学新兴领域的研究; 2）回顾与听力和耳聋相关的分子生物学进展; 3）促进从事分子听觉研究的不同实验室之间以及基础科学家和临床医生之间的互动和合作; 4）鼓励转化研究，可以导致诊断和治疗听力障碍;和5）提供外展到患者的倡导团体和学校在波士顿地区，与教育的遗传学耳聋和听力研究。来自听觉系统之外的演讲者将讨论高通量测序，计算遗传学和HapMap项目，分子进化和疾病映射，视觉系统分子生物学的最新进展以及其他主题的应用。听力课程将包括但不限于：分子遗传学;表观遗传机制;发育;整合基因功能;听力和前庭疾病的分子基础;遗传筛查和基因治疗;以及再生。要求提供支助，为少数群体与会者和受训者提供奖学金，支付一些受邀与会者的旅费，并支助与主办会议有关的其他费用。 项目叙述：部分支持，要求主办第七届会议上的听力和耳聋的分子生物学。会议将于2009年6月在马萨诸塞州波士顿举行。会议的主题包括但不限于：遗传性耳聋的分子遗传学和基因图谱;突变异质性和耳聋表型;功能相关耳聋基因家族;遗传性耳聋的复杂遗传学;听觉发育的分子调控;内耳细胞表型的遗传学;毛细胞转导的分子基础;中枢听觉系统;听觉组织特异性基因活性和表达profilin;耳蜗损伤，再生和修复;耳聋突变的分子诊断;耳科疾病的分子生物学：病因学和治疗。