2009 Gradient Sensing & Directed Cell Migration Gordon Research Conference

2009 梯度传感

• 批准号: 7608789
• 负责人: Anna Huttenlocher
• 金额: $ 0.8万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-02-01 至 2010-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7608789
• 关键词: Address; Allergic; Area; Arthritis; Asthma; Basic Science; Biomedical Engineering; Cardiovascular Diseases; Cell Polarity; Cells; Chemotaxis; Collaborations; Complex; Cytoskeleton; Development; Disease; Environment; Financial Support; Growth Cones; Immigration; Immune; Immune system; Inflammation; Intention; Leukocyte Trafficking; Link; Malignant Neoplasms; Modeling; Neurons; Pathogenesis; Pathway interactions; Public Health; Research; Research Personnel; Scientist; Signal Transduction; System; Texas; Underrepresented Minority; Woman; Wound Healing; abstracting; cell motility; human disease; improved; meetings; neuron development; novel; novel therapeutics; polarized cell; posters; programs; public health relevance; symposium; therapeutic development; trafficking

DESCRIPTION (provided by applicant): The 2009 Gordon Research Conference (GRC) on Gradient sensing and directed cell migration will be held from March 29-April 3, 2009 at Hotel Galvez in Galveston, Texas. The conference follows two successful Gordon Conferences in the field of chemotaxis research, which have been held biennially since 2005. The conference addresses the basic research question of how cells polarize and migrate directionally in diverse systems, including development, neuronal path finding, leukocyte trafficking, wound healing and tissue repair and cancer. The conference is also relevant to the development of therapeutics aimed at disorders where cell migration is central to disease pathogenesis, including cardiovascular diseases, rheumatic and allergic disease, asthma and cancer. The program highlights the commonality of mechanisms that regulate directed cell migration in the context of diverse systems and the implications of these common pathways to the development of disease. The conference will emphasize new concepts about the basic mechanisms that regulate gradient sensing and directed cell migration, and will explore links between cell migration during development, wound healing, immune cell trafficking and cancer. Nine sessions are planned which include (1) Directed cell migration in complex systems, (2) Migration in development and wound healing, (3) Inflammation and leukocyte trafficking, (4) Cell signaling in chemotaxis, (5) Cell polarity and motility in the immune system, (6) Cell polarity and the cytoskeleton in directed cell migration, (7) Modeling and bioengineering in directed cell migration, (8) Directed cell migration in cancer, and (9) Neuronal polarity and growth cone guidance. The combination of speakers and topics has been selected with the specific intention of stimulating new ideas and collaborations in the field of chemotaxis research. The session speakers will emphasize novel unpublished results directly related to gradient sensing and directed cell migration in diverse fields. Young investigators will be encouraged to present and discuss their findings in a supportive environment, by inviting up to 20 additional speakers from submitted abstracts and by holding four poster sessions. We anticipate offering financial support to encourage participation by young scientists, women and underrepresented minorities. Throughout the conference, interaction among senior and young investigators will be promoted in both formal and informal settings. Support of this program will assure that the meeting will be successful and will provide much needed sponsorship for outstanding young scientists who wish to attend the meeting. PUBLIC HEALTH RELEVANCE: The conference addresses the fundamental mechanisms that regulate directed cell migration. This area has substantial importance to the development of new therapeutics to treat a diverse array of human diseases including cardiovascular disease, cancer, arthritis and asthma. The conference on Gradient sensing and directed cell migration will bring together experts that study directed cell migration in simple and complex systems in order to stimulate new ideas and advance our ability to improve public health.

描述（由申请人提供）：2009年戈登研究会议（GRC）梯度传感和定向细胞迁移将于2009年3月29日至4月3日在酒店加尔维斯顿加尔维斯顿，得克萨斯州。该会议是在趋化性研究领域的两次成功的戈登会议之后举行的，自2005年以来每两年举行一次。会议讨论了细胞如何在不同系统中定向迁移和迁移的基本研究问题，包括发育，神经元路径发现，白细胞运输，伤口愈合和组织修复以及癌症。该会议还与针对细胞迁移对疾病发病机制至关重要的疾病的治疗方法的开发相关，包括心血管疾病、风湿性和过敏性疾病、哮喘和癌症。该计划强调了在不同系统的背景下调节定向细胞迁移的机制的共同性以及这些共同途径对疾病发展的影响。会议将强调有关调节梯度感应和定向细胞迁移的基本机制的新概念，并将探讨发育过程中细胞迁移、伤口愈合、免疫细胞贩运和癌症之间的联系。计划举办九次会议，包括（1）复杂系统中的定向细胞迁移，（2）发育和伤口愈合中的迁移，（3）炎症和白细胞运输，（4）趋化性中的细胞信号传导，（5）免疫系统中的细胞极性和运动性，（6）定向细胞迁移中的细胞极性和细胞骨架，（7）定向细胞迁移中的建模和生物工程，（8）癌症中的定向细胞迁移，和（9）神经元极性和生长锥引导。选择演讲者和主题的组合是为了激发趋化性研究领域的新想法和合作。会议发言人将强调新的未发表的结果直接相关的梯度传感和定向细胞迁移在不同领域。将鼓励年轻的研究人员在一个有利的环境中介绍和讨论他们的研究结果，从提交的摘要中再邀请20名发言者，并举行四次海报会议。我们预计将提供财政支持，以鼓励年轻科学家、妇女和代表性不足的少数族裔的参与。在整个会议期间，将在正式和非正式场合促进高级和青年调查员之间的互动。对该计划的支持将确保会议取得成功，并将为希望参加会议的杰出青年科学家提供急需的赞助。 公共卫生相关性：会议讨论了调节定向细胞迁移的基本机制。这一领域对于开发治疗多种人类疾病的新疗法具有重要意义，所述疾病包括心血管疾病、癌症、关节炎和哮喘。梯度传感和定向细胞迁移会议将汇集研究简单和复杂系统中定向细胞迁移的专家，以激发新的想法并提高我们改善公共卫生的能力。