2009 Molecular Approaches for Emergent Re-emergent Tropical Diseases Gordon Resea

2009 年新兴热带病的分子方法 Gordon Resea

• 批准号: 7611715
• 负责人: RICARDO TOSTES GAZZINELLI
• 金额: $ 1.2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-01-26 至 2009-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7611715
• 关键词: Address; Area; Basic Science; Cells; Communities; Country; Development; Disease; Disease Outcome; Economics; Emerging Communicable Diseases; Epidemiology; Goals; Health; Immunity; International; Molecular; Participant; Population; Request for Proposals; Research; Series; Texas; Transgenic Organisms; Tropical Disease; Vaccination; Vector-transmitted infectious disease; chemotherapy; disorder control; environmental change; insight; meetings; member; neglect; pathogen; population migration; posters; programs; resistance mechanism; social; symposium; transmission process; vector

DESCRIPTION (provided by applicant): This proposal requests partial support for a meeting on Molecular Approaches for Emergent / Re-Emergent Tropical Diseases (ETD) as part of the Gordon Research Conference series to be held in Galveston, Texas, January 25-30, 2009. The broad and long-term goal of the conference is to increase our understanding of host-pathogen interactions with the aim of developing new insights for controlling ETDs. The specific aims of this meeting will be to convene 35 speakers that represent critical areas of neglected tropical diseases with a total of 150 participants for a five-day conference in a relatively isolated setting. The program will have two initial keynote addresses and three sections that broadly address current issues of host cell invasion, homing/latency, innate mechanisms of resistance and pathogen transmission and their influence on disease outcome. This will be followed by a second segment of the conference that will deal with more applied issues related to strategies of disease control. The second segment will begin with two keynote addresses on vector-borne diseases and immunological aspects relevant to induction of long-lasting protective immunity by vaccination, followed by sections that deal with the use of transgenic vectors, vaccination, chemotherapy and epidemiology related to the control of ETDs. In addition, two afternoon poster sessions will permit all participants to contribute to these topics. The significance of this application is that the Gordon Research Conference on ETDs provides a forum that brings together and synergizes members of the international research community on topical diseases. The health relatedness of this application is that the discussions will define the important questions on basic science as they relate to the development of new strategies to control the most important tropical diseases. Approximately 1 billion people - one sixth of the world's population - suffer from one or more tropical diseases, contributing to significant political, social and economic instability in the endemic countries. With widespread environmental changes and population migration, numerous of these infectious diseases are emerging and re- emerging in different parts of the world. The health relatedness of this application is that the discussions of current research will define important questions that need to be addressed for development of new strategies to control the ETDs.

描述（由申请人提供）：本提案要求部分支持将于2009年1月25日至30日在德克萨斯州加尔维斯顿举行的戈登研究会议系列会议“紧急/再紧急热带疾病分子方法”（ETD）。本次会议的长远目标是提高我们对宿主-病原体相互作用的认识，为控制外源性疾病发展新的见解。这次会议的具体目标将是在一个相对孤立的环境中召集代表被忽视的热带病关键领域的35名发言者和总共150名与会者，举行为期五天的会议。该计划将有两个初步主题演讲和三个部分，广泛讨论宿主细胞入侵，归巢/延迟，抗性和病原体传播的先天机制及其对疾病结果的影响。随后是会议的第二部分，将讨论与疾病控制战略有关的更多应用问题。第二部分将以两个关于媒介传播疾病和与通过疫苗接种诱导持久保护性免疫有关的免疫学方面的主题演讲开始，然后是涉及转基因媒介的使用、疫苗接种、化学疗法和与控制环境污染排放有关的流行病学的部分。此外，两个下午的海报会议将允许所有参与者对这些主题作出贡献。这一应用的意义在于，戈登外源性疾病研究会议提供了一个论坛，汇集了国际研究界关于局部疾病的成员并使其协同工作。这一应用与健康的关系在于，讨论将界定基础科学中的重要问题，因为这些问题与控制最重要的热带病的新战略的发展有关。约有10亿人——占世界人口的六分之一——患有一种或多种热带病，在流行国家造成严重的政治、社会和经济不稳定。随着广泛的环境变化和人口迁移，这些传染病在世界不同地区不断出现和重新出现。这一应用与健康的关系是，对当前研究的讨论将确定需要解决的重要问题，以便制定新的战略来控制排放物排放。