2009 Cardiac Arrhythmia Mechanisms Gordon Research Conference

描述(由申请人提供)： 请求为将于2008年2月15日至20日在意大利布拉加的Il Ciocco举行的2009年关于心律失常机制的戈登研究会议(GRC)提供部分支持。这是戈登关于心律失常机制的第四次研究会议。会议每两年召开一次，上一次会议分别于2003年、2005年和2007年举行。这些会议为国际科学讨论心律紊乱和致命性心律失常的机制以及治疗和预防的新方法提供了一个场所。GRC会议使我们的科学界异乎寻常地合作和互动，从而深刻地影响了我们的科学界。他们吸引了我们社会各个方面的参与，从研究生和博士后研究员到高级教员，国内和国际的参与，以及学术界和工业界的参与，成功地解决了抗击心脏性猝死的主要问题。2007年举行的上一次会议的总分为1.2分，从1分(最好)到5分(最差)。我们对2007年全球心律失常机制会议与会者的出色评价感到非常高兴，我们将努力保持甚至超过前一次会议的质量。 拟议的2009年戈登心律失常机制研究会议将聚焦于基础科学和临床相关的关键科学主题。这次会议将提供独特的机会，让各相关领域的杰出研究人员和专家汇聚一堂，包括分子生物学、分子遗传学、细胞电生理学、生物物理学、成像、生物医学工程、数学和临床心脏病学，就威胁生命的复杂心律失常的潜在机制进行交流和分享想法。2007年会议的与会者表示，他们希望引导2009年的会议转向心律失常机制研究的临床翻译。因此，我们2009年GRC的主题是心律失常研究的翻译方面。对拟议专题以及发言者和讨论负责人的选择反映了这一重点。每堂课的组织确保演讲者的顺序将以系统和说教的方式引导听众了解给定主题在基因、蛋白质、细胞、器官和有机体的水平上的知识，最终由临床医生/科学家进行演讲，将所提出的主题整合并转化为临床研究和实践。这些报告将定义和分析有关心律失常机制的最新和最重要的信息，以及这些信息如何导致新的抗心律失常疗法和预防。我们打算邀请各自领域的顶尖专家和年轻的有前途的研究人员参加这个论坛，在那里他们将介绍并共同讨论对了解心律失常机制最令人兴奋的新贡献。 将特别注意增加青年研究人员以及妇女和少数群体研究人员的参与。这项提议概述了增加现有调查人员和年轻调查人员之间非正式互动的新方法。拟议的初步计划还将针对成熟的和年轻的女性调查人员。

DESCRIPTION (provided by applicant): Partial support is requested for the 2009 Gordon Research Conference (GRC) on Cardiac Arrhythmia Mechanisms, to be held February 15-20, 2008 at Il Ciocco, Braga, Italy. This is the fourth Gordon Research Conference on Cardiac Arrhythmia Mechanisms. The meeting convenes biannually, with past meeting held in 2003, 2005, and 2007. These meetings provide a venue for international scientific discourse on the mechanisms that underlie disturbances in cardiac rhythm and lethal arrhythmias, and the novel approaches to therapy and prevention. The GRC meetings have profoundly affected our scientific community by rendering it unusually collaborative and interactive. They draw participation from every aspect of our community, from graduate students and postdoctoral fellows through to senior faculty, with participation both national and international, and from academia and industry, to successfully address major issues in the fight against sudden cardiac death. The overall score of the previous conference held in 2007 was 1.2 on a scale of 1 (best) to 5 (worst). We are extremely pleased with the outstanding ratings by the participants of the 2007 GRC on Cardiac Arrhythmia Mechanisms, and we will work hard to maintain and even surpass the quality of the preceding meeting. The proposed 2009 Gordon Research Conference on Cardiac Arrhythmia Mechanisms will focus on both basic science and clinically relevant key scientific topics. The meeting will allow unique opportunities to bring together groups of outstanding investigators, experts in various relevant fields, including molecular biology, molecular genetics, cellular electrophysiology, biophysics, imaging, biomedical engineering, mathematics, and clinical cardiology to interact and share ideas about the underlying mechanisms of complex life-threatening cardiac arrhythmias. The participants of the 2007 conference expressed their desire to steer the 2009 conference towards the clinical translation of cardiac arrhythmia mechanisms research. Accordingly, the Theme of our 2009 GRC is Translational Aspects of Cardiac Arrhythmias Research. The selection of proposed topics as well as speakers and discussion leaders reflects this emphasis. The organization of each session ensures that the sequence of speakers will lead the audience through what is known about a given subject at the level of the gene, the protein, the cell, the organ, and the organism in a systematic and didactic way, culminating with a presentation by a clinician/scientist that integrates and translates the presented topics into clinical research and practice. The presentations will define and analyze the latest and most important information on arrhythmia mechanisms and how these could result in novel antiarrhythmia therapies and prevention. We intend to invite the top experts and young promising investigators in their respective fields to this forum, where they will present and together discuss the most exciting new contributions to the understanding of the mechanisms of cardiac rhythm disturbances. Specific attention will be paid to increasing the participation of young investigators and well as women and minority researchers. This proposal outlines novel approaches to increasing the informal interaction between established and young investigators. The proposed preliminary program will also target both established and young female investigators.