SOUTHWEST ONCOLOGY GROUP - OPERATIONS OFFICE

西南肿瘤学集团 - 运营办公室

• 批准号: 7933285
• 负责人: LAURENCE HOWARD BAKER
• 金额: $ 69万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2011-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7933285
• 关键词: Achievement; Adjuvant; Adult; Advocate; African American; Anthracyclines; Asian Americans; Biological Assay; Canada; Cancer Patient; Cancer Survivor; Cancer Therapy Evaluation Program; Clinical; Clinical Research; Clinical Trials; Community Clinical Oncology Program; Conflict of Interest; Cyclophosphamide; Development; Disease; Disease-Free Survival; Doxorubicin; Education; Ethics; Fluorouracil; Funding; Gynecology; Hispanic Americans; Hospitals; Institution; Laboratory Research; Malignant Female Reproductive System Neoplasm; Malignant Neoplasms; Medical Oncology; Methods; Minority; Minority Groups; Modality; Monitor; Morals; Online Systems; Operative Surgical Procedures; Outcome; Patients; Performance; Phase; Policies; Population; Positive Lymph Node; Postmenopause; Prevention; Prognostic Factor; Publications; Randomized; Reporting; Research; Research Personnel; Resources; Role; Safety; Science; Southwest Oncology Group; System; Tamoxifen; Technology; Therapeutic; Therapeutics Committee; Training; Tumor Bank; Urologic Cancer; Woman; anticancer research; base; cancer prevention; chemotherapy; data integrity; high risk; innovation; malignant breast neoplasm; member; named group; older men; outreach program; prevent; programs; quality assurance; response; sarcoma; sound; statistical center

DESCRIPTION (provided by applicant): The Southwest Oncology Group is an adult, multi-disease, multi-modality clinical cancer research organization with 35 Member Institutions, 29 Community Clinical Oncology Program (CCOP) institutions, including 7 Minority-Based CCOPs, 27 Urologic Cancer Outreach Program (UCOP) members, and a network of 1,036 Affiliate Program investigators at 189 offices and hospitals, and 12 institutions participating in the CTEP Minority program. A special emphasis of the Group is managed by the renamed Committee on Special Populations, established in 1992. The committee's research and education agenda has broadened to include: women (or men), older cancer patients, cancer survivors, and racial/ethnic minority groups (African-American, Hispanic Americans and Asian American Pacific Islanders). Involving patient advocates in Group activities is an important role of this committee. The committee report details the cross-committee research and publications. The moral and ethical conduct of clinical research by the group members is emphasized by ethics training, the conflict of interest policy, affirmation of integrity and data and safety monitoring. In addition to the presentation of correlative sciences activities tied to tumor banks related to disease committees, we propose a Correlative Sciences Committee, which will provide oversight of science and quality assurance of assay technology across the six disease committee correlative science programs in the Group. There are three new initiatives in this application. Two new adult medical oncology Intergroup proposals, one dealing with advanced gynecologic cancer, the U.S. Gynecology Intergroup, and the second dealing with sarcomas, The U.S./Canada Sarcoma Intergroup. The third is the Early Therapeutics Committee, which will take advantage of the 10 institutions in the Group who hold Phase I NCI funded U-01s. This will be possible with the new Web-Based, Multi-User Phase I Monitoring System implemented by our Statistical Center.

描述（申请人提供）：西南肿瘤学小组是一个成人，多疾病，多模态临床癌症研究组织，拥有35个成员机构，29个社区临床肿瘤学计划（CCOP）机构，包括7个少数民族CCOP，27个泌尿系统癌症外展计划（UCOP）成员，以及189个办事处和医院的1，036名附属计划研究者网络，和12个机构参与CTEP少数民族计划。 该小组的一个特别重点是由1992年成立的改名为特殊人口委员会管理。该委员会的研究和教育议程已扩大到包括：妇女（或男子），老年癌症患者，癌症幸存者和种族/少数民族群体（非洲裔美国人，西班牙裔美国人和亚裔美国人太平洋岛民）。让患者倡导者参与小组活动是该委员会的一个重要角色。委员会报告详细介绍了跨委员会的研究和出版物。 通过伦理培训、利益冲突政策、对完整性和数据的确认以及安全性监测，强调小组成员在临床研究中的道德和伦理行为。 除了介绍与疾病委员会相关的肿瘤库相关的相关科学活动外，我们还提出了一个相关科学委员会，该委员会将在集团的六个疾病委员会相关科学项目中提供科学监督和检测技术的质量保证。 此次申请有三项新举措。两个新的成人医学肿瘤学国际小组提案，一个涉及晚期妇科癌症，美国妇科国际小组，第二个涉及肉瘤，美国/加拿大肉瘤国际组织。第三个是早期治疗委员会，该委员会将利用集团中持有第一阶段NCI资助的U-01的10个机构。我们的统计中心实施了新的基于网络的多用户第一阶段监测系统，这将成为可能。