3 U24DK076126 -04 W1

3 U24DK076126 -04 W1

基本信息

  • 批准号:
    7930219
  • 负责人:
  • 金额:
    $ 36.4万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2009
  • 资助国家:
    美国
  • 起止时间:
    2009-09-25 至 2011-08-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION, OVERALL (provided by applicant): The major goal of the Mouse Metabolic Phenotyping Center at the University of Washington is to promote and facilitate the study of animal models of obesity, diabetes and pathological complications due to these disorders. Because of the multidisciplinary nature of phenotyping approaches, close interaction across medical, pathological, and molecular disciplines is necessary to characterize animals used to study human diseases. By providing a number of Core facilities, the Seattle MMPC integrates and coordinates research activities so that Customers interested in having their animal models characterized can obtain a dear picture of the metabolic and disease state for each animal. The five Cores are: 1) an Administrative Core that is responsible for the day-to-day administration of the MMPC including the Pilot & Feasibility Program of the Animal Models of Diabetic Complications Consortium (AMDCC); 2) an Animal Core which will ensure proper delivery of animals and appropriate distribution to other Cores, and monitor health, husbandry and proper treatment of animals; 3) a Diabetes and Energy Balance Core to provide facilities for measuring body composition, energy expenditure, metabolic phenotyping and evaluation of type 1 and type 2 diabetes; 4) a Cardiovascular Core to provide assessment of heart function in normal and challenged states, vascular pathology quantifications, and response to injury modeling; 5) a Microvascular and Retinopathy Core which will evaluate kidney function and structural changes as well as extent of pathology in the eye. Four of the Core units are supported by HUBs which collect within each HUB, general technologies. Within the Animal Core is the Animal HUB which provides personnel to aid in dispersal of animals to the appropriate core facilities and to aid investigators in phenotyping. The Diabetes and Energy Balance Core harbors the Analytical HUB which is responsible for quantification of RNA, proteins, carbohydrates, and any other analyte needed in this MMPC. The Surgery HUB is within the Cardiovascular Core and provides surgery expertise for this Core and any surgery needs extending from other Cores. The Morphology HUB, located within the Microvascular/Retinopathy Core, is responsible for all tissue preparation and analysis. Thus, this MMPC provides outstanding facilities and support for the large and varied obesity and diabetes research base which includes our University, AMDCC investigators, and other potential Customers across the country.
总体描述(由申请人提供):

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

RENEE C LEBOEUF其他文献

RENEE C LEBOEUF的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('RENEE C LEBOEUF', 18)}}的其他基金

Genetic Predisposition for Intimal Hyperplasia in Mice
小鼠内膜增生的遗传倾向
  • 批准号:
    8111887
  • 财政年份:
    2010
  • 资助金额:
    $ 36.4万
  • 项目类别:
Genetic Predisposition for Intimal Hyperplasia in Mice
小鼠内膜增生的遗传倾向
  • 批准号:
    8279326
  • 财政年份:
    2010
  • 资助金额:
    $ 36.4万
  • 项目类别:
Genetic Predisposition for Intimal Hyperplasia in Mice
小鼠内膜增生的遗传倾向
  • 批准号:
    8469077
  • 财政年份:
    2010
  • 资助金额:
    $ 36.4万
  • 项目类别:
Genetic Predisposition for Intimal Hyperplasia in Mice
小鼠内膜增生的遗传倾向
  • 批准号:
    7983436
  • 财政年份:
    2010
  • 资助金额:
    $ 36.4万
  • 项目类别:
Anti-inflammatory, cholesterol export, and cardioprotective functions of ABCA1
ABCA1 的抗炎、胆固醇输出和心脏保护功能
  • 批准号:
    8217251
  • 财政年份:
    2009
  • 资助金额:
    $ 36.4万
  • 项目类别:
Anti-inflammatory, cholesterol export, and cardioprotective functions of ABCA1
ABCA1 的抗炎、胆固醇输出和心脏保护功能
  • 批准号:
    7759216
  • 财政年份:
    2009
  • 资助金额:
    $ 36.4万
  • 项目类别:
Anti-inflammatory, cholesterol export, and cardioprotective functions of ABCA1
ABCA1 的抗炎、胆固醇输出和心脏保护功能
  • 批准号:
    8415968
  • 财政年份:
    2009
  • 资助金额:
    $ 36.4万
  • 项目类别:
Anti-inflammatory, cholesterol export, and cardioprotective functions of ABCA1
ABCA1 的抗炎、胆固醇输出和心脏保护功能
  • 批准号:
    8020964
  • 财政年份:
    2009
  • 资助金额:
    $ 36.4万
  • 项目类别:
Core B and Tissue Core
核心B和组织核心
  • 批准号:
    7548839
  • 财政年份:
    2008
  • 资助金额:
    $ 36.4万
  • 项目类别:
Role for S1P2 in the Arterial Injury Response
S1P2 在动脉损伤反应中的作用
  • 批准号:
    8300956
  • 财政年份:
    2008
  • 资助金额:
    $ 36.4万
  • 项目类别:

相似海外基金

The earliest exploration of land by animals: from trace fossils to numerical analyses
动物对陆地的最早探索:从痕迹化石到数值分析
  • 批准号:
    EP/Z000920/1
  • 财政年份:
    2025
  • 资助金额:
    $ 36.4万
  • 项目类别:
    Fellowship
Animals and geopolitics in South Asian borderlands
南亚边境地区的动物和地缘政治
  • 批准号:
    FT230100276
  • 财政年份:
    2024
  • 资助金额:
    $ 36.4万
  • 项目类别:
    ARC Future Fellowships
The function of the RNA methylome in animals
RNA甲基化组在动物中的功能
  • 批准号:
    MR/X024261/1
  • 财政年份:
    2024
  • 资助金额:
    $ 36.4万
  • 项目类别:
    Fellowship
Ecological and phylogenomic insights into infectious diseases in animals
对动物传染病的生态学和系统发育学见解
  • 批准号:
    DE240100388
  • 财政年份:
    2024
  • 资助金额:
    $ 36.4万
  • 项目类别:
    Discovery Early Career Researcher Award
RUI:OSIB:The effects of high disease risk on uninfected animals
RUI:OSIB:高疾病风险对未感染动物的影响
  • 批准号:
    2232190
  • 财政年份:
    2023
  • 资助金额:
    $ 36.4万
  • 项目类别:
    Continuing Grant
RUI: Unilateral Lasing in Underwater Animals
RUI:水下动物的单侧激光攻击
  • 批准号:
    2337595
  • 财政年份:
    2023
  • 资助金额:
    $ 36.4万
  • 项目类别:
    Continuing Grant
A method for identifying taxonomy of plants and animals in metagenomic samples
一种识别宏基因组样本中植物和动物分类的方法
  • 批准号:
    23K17514
  • 财政年份:
    2023
  • 资助金额:
    $ 36.4万
  • 项目类别:
    Grant-in-Aid for Challenging Research (Exploratory)
Analysis of thermoregulatory mechanisms by the CNS using model animals of female-dominant infectious hypothermia
使用雌性传染性低体温模型动物分析中枢神经系统的体温调节机制
  • 批准号:
    23KK0126
  • 财政年份:
    2023
  • 资助金额:
    $ 36.4万
  • 项目类别:
    Fund for the Promotion of Joint International Research (International Collaborative Research)
Using novel modelling approaches to investigate the evolution of symmetry in early animals.
使用新颖的建模方法来研究早期动物的对称性进化。
  • 批准号:
    2842926
  • 财政年份:
    2023
  • 资助金额:
    $ 36.4万
  • 项目类别:
    Studentship
Study of human late fetal lung tissue and 3D in vitro organoids to replace and reduce animals in lung developmental research
研究人类晚期胎儿肺组织和 3D 体外类器官在肺发育研究中替代和减少动物
  • 批准号:
    NC/X001644/1
  • 财政年份:
    2023
  • 资助金额:
    $ 36.4万
  • 项目类别:
    Training Grant
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了