Biostatistics

生物统计共享服务 生物统计共享服务的目标是提供基础、转换、临床和流行病学 马里兰大学马琳和斯图尔特·格林鲍姆癌症中心(UMGCC)的研究人员 获得高质量的统计科学。共享服务的功能包括设计、审查和 监测方案.统计分析、计划和报告.设计和分析高维数据 数据，包括微阵列基因表达、单核苷酸多态性(SNPs)、表观遗传学、 蛋白质组学；准备赠款申请和手稿；提供生物统计学培训和建议 临床数据管理；以及数据库计算。生物统计共享服务为研究人员提供 在UMGCC，拥有先进的统计方法和专业知识，由 国家癌症研究所，如联合研究的设计和分析，微阵列和 癌症流行病学数据和SNP数据挖掘。这项共享服务中的统计员与 UMGCC所有三个癌症项目的研究人员：实验治疗，激素反应 癌症、分子和结构生物学。共享服务可以访问出色的计算 资源和统计软件包(如SAS、StatXact、sPlus)、数据库管理软件 (例如，Access、OnCore)和专门的统计软件，以有效和有效地支持 UMGCC的计划。 从2006年7月至2007年6月，这一共享服务支持了来自60名调查人员和 42份拨款申请。近55%的总努力花在了资助的癌症项目上。对于这笔赠款， 我们要求生物统计和生物信息学支持的全职当量(FTE)为0.50，全职当量为0.25 FTE 行政和数据库援助，为每种癌症提供生物统计和生物信息学支持 UMGCC的项目。

Biostatistics Shared Service The goal of the Biostatistics Shared Service is to provide basic, translational, clinical, and epidemiology investigators at the University of Maryland Marlene and Stewart Greenebaum Cancer Center (UMGCC) with access to high quality statistical science. Functions of the shared service include designing, reviewing, and monitoring protocols; statistical analysis, planning, and reporting; designing and analyzing high dimensional data, including microarray gene expression, single nucleotide polymorphisms (SNPs), epigenetics, proteomics; preparing grant applications and manuscripts; providing biostatistics training and advice on clinical data management; and database computing. The Biostatistics Shared Service provides investigators at UMGCC with advanced statistical methods and expertise developed under other grants funded by the National Cancer Institute, such as design and analysis of combination studies, analysis of microarray and cancer epidemiology data, and SNP data mining. Statisticians in this shared service collaborate with investigators in all three cancer programs at UMGCC: Experimental Therapeutics, Hormone Responsive Cancers, and Molecular and Structural Biology. The shared service has access to excellent computing resources and statistical software packages (e.g., SAS, StatXact, Splus), database management software (e.g., Access, Oncore¿), and specialized statistical software necessary for efficient and effective support of UMGCC's programs. From July 2006 to June 2007, this shared service supported 128 projects from 60 investigators and 42 grant applications. Nearly 55 percent of total effort was spent on fund.ed cancer projects. For this grant, we request 0.50 full-time equivalent (FTE) of biostatistics and bioinformatics support and 0.25 FTE of administrative and database assistance to provide biostatistics and bioinformatics support to each cancer program at UMGCC.