UMB Technology Resource Center

描述（由申请人提供）：医学（UMSOM）的马里兰州大学（UMSOM）建议翻新27,000总平方英尺的实验室，办公室和会议空间的第六和第七层的弗兰克C。Bressler研究大楼（BRB）。拟议的改造项目将针对几个研究核心的整合，并为将成为UMB技术资源中心（TRC）的其他资源实验室创造新的空间。对BRB六楼的改造将巩固成像技术，包括整体动物成像，共聚焦显微镜和电子显微镜，提供一个全面的成像中心。BRB七楼的翻修将合并八个核心设施和两个流式细胞仪设施。这些核心包括：（1）BIAcore核心设施;（2）生物聚合物/基因组学核心设施;（3）细胞因子核心实验室;（4）流式细胞术，将Greenebaum癌症中心和疫苗开发中心的流式细胞术资源结合在一起;（5）病理学生物储存和研究核心;（6）蛋白质组学核心设施;（7）转基因和敲除核心设施;以及（8）转化核心实验室。BRB的七楼还将包括新的临床资源实验室：（1）临床基因组学实验室;（2）人类细胞分选实验室和（3）多用途临床实验室。装修将基于开放实验室的概念。使用共享的开放实验室将允许核心之间更好的协作，特别是那些共享共同主题的核心。TRC将促进多学科的方法，以支持在UMSOM不断增加，强大的研究环境。它的目的是，这一改造成为一个校园范围内的整合过程的核心。

DESCRIPTION (provided by applicant): The University of Maryland School of Medicine (UMSOM) proposes to renovate 27,000 gross square feet of lab, office, and conference space on the sixth and seventh floors of the Frank C. Bressler Research Building (BRB). The proposed renovation project will target the consolidation of several research cores and create new space for additional resource labs in what will become the UMB Technology Resource Center (TRC). Renovations to the sixth floor of BRB will consolidate imaging technologies, including whole animal imaging, confocal microscopy, and electron microscopy, providing a comprehensive imaging center. Renovations to the seventh floor of BRB will consolidate eight core facilities and consolidate two flow cytometry facilities. Those cores include: (1) BIAcore Core Facility; (2) Biopolymer/Genomics Core Facility; (3) Cytokine Core Laboratory; (4) Flow Cytometry, joining together the Greenebaum Cancer Center and the flow cytometry resources of the Center for Vaccine Development; (5) Pathology Biorepository and Research Core; (6) Proteomics Core Facility; (7) Transgenic and Knockout Core Facility; and (8) Translational Core Laboratory. The seventh floor of BRB will also include new clinical resource labs: (1) Clinical Genomics Laboratory; (2) Human Cell Sorting Laboratory, and (3) Multiuse Clinical Laboratory. Renovations will be based on an open-lab concept. The use of shared, open labs will allow better collaboration between cores, especially those that share common themes. The TRC will promote a multidisciplinary approach to support an ever increasing, robust research environment at UMSOM. It is intended that this renovation become the centerpiece of a campus-wide consolidation process.