UMB Technology Resource Center

描述（由申请人提供）：马里兰大学医学院（UMSOM）提议在Frank C. Bressler研究大楼（BRB）的六层和七层翻新27,000总平方英尺的实验室，办公室和会议空间。拟议的改造项目将针对几个研究核心的整合，并为额外的资源实验室创造新的空间，这将成为UMB技术资源中心（TRC）。BRB六楼的翻新将整合成像技术，包括全动物成像、共聚焦显微镜和电子显微镜，提供一个综合成像中心。BRB七楼的翻新将整合八个核心设施和两个流式细胞仪设施。这些核心包括：(1)BIAcore核心设施；(2)生物聚合物/基因组学核心设施；(3)细胞因子核心实验室；(4)流式细胞术，将格林鲍姆癌症中心和疫苗开发中心的流式细胞术资源结合起来；(5)病理生物库与研究中心；(6)蛋白质组学核心设施；(7)转基因和敲除核心设施；(8)转化核心实验室。BRB的七楼还将包括新的临床资源实验室：(1)临床基因组学实验室；(2)人类细胞分选实验室；(3)多功能临床实验室。翻新将基于开放实验室的概念。使用共享的、开放的实验室将允许内核之间更好的协作，特别是那些共享共同主题的内核。TRC将促进多学科方法，以支持联索管理学院不断增长的、强大的研究环境。它的目的是使这次改造成为整个校园整合过程的核心。

DESCRIPTION (provided by applicant): The University of Maryland School of Medicine (UMSOM) proposes to renovate 27,000 gross square feet of lab, office, and conference space on the sixth and seventh floors of the Frank C. Bressler Research Building (BRB). The proposed renovation project will target the consolidation of several research cores and create new space for additional resource labs in what will become the UMB Technology Resource Center (TRC). Renovations to the sixth floor of BRB will consolidate imaging technologies, including whole animal imaging, confocal microscopy, and electron microscopy, providing a comprehensive imaging center. Renovations to the seventh floor of BRB will consolidate eight core facilities and consolidate two flow cytometry facilities. Those cores include: (1) BIAcore Core Facility; (2) Biopolymer/Genomics Core Facility; (3) Cytokine Core Laboratory; (4) Flow Cytometry, joining together the Greenebaum Cancer Center and the flow cytometry resources of the Center for Vaccine Development; (5) Pathology Biorepository and Research Core; (6) Proteomics Core Facility; (7) Transgenic and Knockout Core Facility; and (8) Translational Core Laboratory. The seventh floor of BRB will also include new clinical resource labs: (1) Clinical Genomics Laboratory; (2) Human Cell Sorting Laboratory, and (3) Multiuse Clinical Laboratory. Renovations will be based on an open-lab concept. The use of shared, open labs will allow better collaboration between cores, especially those that share common themes. The TRC will promote a multidisciplinary approach to support an ever increasing, robust research environment at UMSOM. It is intended that this renovation become the centerpiece of a campus-wide consolidation process.