2023 Red Cells Gordon Research Conference

项目摘要 我们为2023年红细胞戈登研究会议（GRC）寻求资金，该会议将于6月4日至9日在 Salve Regina University in纽波特，RI.红细胞GRC成立于1979年，是一个国际论坛， 用于介绍红细胞生物学的最新未发表数据。它汇集了一个多元化的社区 来自学术界、政府和工业界的研究人员，从受训人员到高级人员， investigators.它提供了一个独特的环境，讨论研究和培训机会， 通过与来自学术机构、工业界和 授权机构。戈登会议的形式提供了一个轻松的气氛，在一个学院的场地， 来自红细胞生物学各个领域的研究人员可以相互交流并开展跨学科合作。的 地点为2023年GRC，萨尔夫里贾纳大学在纽波特，RI，交通便利，约74英里， 波士顿国际机场。红细胞GRC在展示创新尖端技术方面有着悠久的历史， 研究红细胞生物学。值得注意的是，许多这些结果已被证明是广泛适用于 生物学和医学的所有领域。本次会议的成功是由于非正式的GRC气氛， 促进社会和智力的互动，导致新的合作科学。2023年的主题 红细胞GRC包括发育性红细胞生成和干细胞生物学，其包括使用ES和 iPS细胞研究红细胞发育。分析调节正常和扰动的机制 红系祖细胞发育和终末分化，铁转运和 利用和影响的感染和炎症红细胞输出和更新的独特细胞生物学 红细胞膜细胞骨架的变化也将被讨论。会议将举行会议， 重点介绍了红细胞生物学中单细胞分析的新方法，以及 转录因子、表观遗传学和染色质结构。会议将补充这些会议 并讨论了红系疾病的新兴治疗和疗法。此外，我们将有两个 杰出的主旨发言人Len Zon和Merav Socolovsky将重点介绍该领域的最新进展。 会议还将针对受训人员和初级调查人员进行编程，并提供独特的 学员和资深调查员之间有意义的互动机会。总的来说，红细胞 GRC通过促进对红细胞生物学的研究，为NIH提供了一项重要的使命， 改善红细胞疾病的治疗方法，并加强该领域新研究人员的招募， 通过支持、鼓励和接触创新研究。

Project Summary We seek funding for the 2023 Red Cells Gordon Research Conference (GRC), which will be held on June 4-9 at Salve Regina University in Newport, RI. The Red Cells GRC was initiated in 1979 and is an international forum for the presentation of the latest unpublished data on erythroid biology. It brings together a diverse community of researchers from academia, government and industry at all levels of expertise from trainees to senior investigators. It provides a unique environment for the discussion of research and opportunities for trainee professional development through panel discussions with mentors from academic institutions, industry and granting agencies. The Gordon Conference format provides a relaxed atmosphere at a collegial venue where researchers from all areas of erythroid biology can interact and develop interdisciplinary collaborations. The venue for the 2023 GRC, Salve Regina University in Newport, RI, is conveniently located about 74 miles from Boston's international airport. The Red Cells GRC has a long history of showcasing innovative cutting-edge research into erythroid biology. Remarkably, many of these results have proven to become widely applicable to all areas of biology and medicine. The success of this meeting is due to the informal GRC atmosphere that promotes social as well as intellectual interactions that lead to novel collaborative science. Topics for the 2023 Red Cells GRC include developmental erythropoiesis and stem cell biology, which includes the use of ES and iPS cells to study erythroid development. Analysis of the mechanisms that regulate normal and perturbed erythroid progenitor cell development and terminal differentiation, the interplay between iron transport and utilization and the effects of infection and inflammation of erythroid output and updates on the unique cell biology of the erythrocyte membrane cytoskeleton will also be discussed. The conference will feature sessions that highlight new methods for single cell analysis in erythroid biology and the regulation gene expression by transcription factors, epigenetics and chromatin architecture. The conference will complement these sessions with discussion of emerging treatments and therapies for erythroid disorders. In addition, we will have two distinguished keynote speakers, Len Zon and Merav Socolovsky, who will highlight recent advances in the field. The meeting will also feature programing targeted to trainees and junior investigators, and provide unique opportunities for meaningful interactions between trainees and established investigators. Overall, the Red Cells GRC serves an import mission to the NIH by promoting research into erythroid biology, which will lead to new and improved treatments for erythroid disorders and by enhancing the recruitment of new researchers in the field through support, encouragement and exposure to innovative research.