RRSS#13: Health, Eating, Activity and Lifestyle study (HEAL)

HEAL研究是一项前瞻性队列研究，通过三个SEER登记中心（Fred哈钦森癌症研究中心（FHCRC），西雅图，华盛顿州，新墨西哥州大学和南加州大学）招募乳腺癌患者，以评估体重、体力活动、饮食、内源性激素和乳腺癌预后因素的相关性。该研究已纳入1183例0-3a期乳腺癌病例，并已完成10年随访活动。随访分为主动（24个月、60个月和10年，以确定复发和更新暴露变量）和被动（每年通过相应的SEER登记研究进行生命状态和第二次主要随访）。

The HEAL Study is a prospective cohort study of breast cancer patients recruited through three SEER registries (Fred Hutchinson Cancer Research Center (FHCRC), Seattle, WA, University of New Mexico, and University of Southern California) to assess the associations of weight, physical activity, diet, endogenous hormones, and prognostic factors for breast cancer. The study has enrolled 1183 Stage 0-3a breast cancer cases and has completed 10 year follow-up activities. Follow-up is both active (24- , 60-months, and 10-years to determine recurrences and update exposure variables) and passive (yearly through the respective SEER registries for vital status and second primaries).