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HIV and Related High-risk Behaviors among Commercial Sex Male Clients in China

中国男性嫖客中的艾滋病毒及相关高危行为

基本信息

批准号：
7923521
负责人：
CUNLIN WANG
金额：
$ 9.05万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-22 至 2010-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7923521
关键词：
AIDS/HIV problem Address Adult Alcohol consumption Area Attitude Behavior Characteristics China Cities Client Communities Consequences of HIV Cross-Sectional Studies Data Developed Countries Developing Countries Drug abuse Drug usage Environment Epidemic Female Frequencies General Population Goals HIV HIV Infections HIV diagnosis HIV/STD Heterosexuals Homosexuals Illicit Drugs Incidence Individual Injecting drug user Intervention Knowledge Life Methods Mission Modeling Pattern Perception Phase Population Prevalence Prostitution Public Health Reporting Research Risk Risk Behaviors Risk Factors Risk-Taking Role Sex Behavior Sexual Partners Social Network Surveys Testing United States National Institutes of Health Viral Visit Work antiretroviral therapy base behavior change health belief high risk high risk behavior instrument male men sex transmission process

项目摘要

DESCRIPTION (provided by applicant): The long-term goals of the project are to (1) Characterize HIV-related high-risk behaviors (heterosexual, drug abuse, homosexual) among commercial sex male clients (CSMCs) population; determine the prevalence and interacting effect of these behaviors, and identify associated factors from both community and individual level. (2) Determine, through the community-based research, HIV prevalence and incidence among CSMCs. Identify the risk and mechanisms of spreading HIV/STD through this "bridge" population to general public; and explore effective community-based intervention strategies (3) Investigate their high-risk behavior change after HIV diagnosis and the risk of secondary HIV infection; and address issues associated with a nti retro viral therapy. The specific aims of this study are to (1) Qualitatively study HIV-related high-risk behavior, including heterosexual, homosexual and drug abuse, as well as their interaction on unprotected heterosexual practice among commercial sex male clients (CSMCs) with the expanded Health Belief Model (HBM). (2) Quantitatively determine the characteristics of CSMCs; the prevalence of HIV-related risky behaviors; and factors contributing to high-risk heterosexual behavior in the aspects of community environment, social network and individual characteristics/knowledge/perception/other risk-taking behavior among CSMCs; and determine the prevalence of HIV infection in CSMCs and their associated factors. Initially, two cities with HIV epidemic, one due to commercial sex and another due to both commercial sex and drug abuse, will be selected and mixed method will be used. In the first phase, qualitative study will be conducted among CSMCs at both cities to explore their HIV-related high-risk behavior, refine conceptual framework and develop instrument for subsequent quantitative study. Then community-based cross-sectional study will be conducted among CSMCs for the prevalence of HIV high-risk behavior, prevalence of HIV infection and associated factors from community and individual perspectives. Our study will be one of pioneer studies in China that address male heterosexual HIV transmission, also a necessary step for exploring effective community-base intervention. Given the catastrophic consequence of HIV epidemic, and valuable information that will be collected from this study which can be applied to other developing countries facing similar epidemic pattern, the public health significance of this study perfectly fit the mission of NIH.

项目描述（由申请人提供）：该项目的长期目标是（1）描述商业性男性客户（CSMCs）人群中与HIV相关的高危行为（异性恋，吸毒，同性恋）;确定这些行为的流行程度和相互作用，并从社区和个人层面确定相关因素。(2)通过以社区为基础的研究，确定社区医务工作者中的艾滋病毒流行率和发病率。明确HIV/STD通过这一“桥梁”人群向公众传播的风险和机制;探索有效的社区干预策略。（3）调查HIV确诊后高危行为改变和继发HIV感染的风险;解决抗逆转录病毒治疗相关问题。本研究的具体目的是：（1）定性研究商业性性行为男性顾客（CSMCs）与HIV相关的高危行为，包括异性性行为、同性性行为和药物滥用，以及它们与无保护的异性性行为的相互作用。(2)定量分析确定CSMCs的特征; HIV相关危险行为的发生率;从社区环境、社会网络和个体特征/知识/认知/其他危险行为等方面分析CSMCs发生高危异性性行为的影响因素;确定CSMCs的HIV感染率及其相关因素。最初，将选择两个艾滋病毒流行的城市，一个是由于商业性行为，另一个是由于商业性行为和药物滥用，并将使用混合方法。在第一阶段，将在两个城市的CSMCs中进行定性研究，以探索他们与艾滋病相关的高危行为，完善概念框架，并为随后的定量研究开发工具。然后以社区为基础，从社区和个人两个角度对社区医务人员HIV高危行为、HIV感染率及其影响因素进行横断面研究。我们的研究将是中国解决男性异性性传播艾滋病病毒的先驱研究之一，也是探索有效的社区干预的必要步骤。考虑到艾滋病流行的灾难性后果，以及从这项研究中收集的有价值的信息，这些信息可以应用于面临类似流行模式的其他发展中国家，这项研究的公共卫生意义完全符合NIH的使命。