Intermittent Exercise and Symptom Management in Breast Cancer Survivors

乳腺癌幸存者的间歇性运动和症状管理

基本信息

  • 批准号:
    7881689
  • 负责人:
  • 金额:
    $ 13.01万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2009
  • 资助国家:
    美国
  • 起止时间:
    2009-07-01 至 2014-06-30
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): This is a resubmission of an NCI K07 Career Development Award. Lynette Craft, PhD is a kinesiologist seeking to redirect her career to cancer prevention and control. Her current work focuses on the use of exercise as an adjunct treatment for women with clinical depression. The proposed award will provide the necessary education in cancer survivorship, strategies for behavior change, the assessment of patient reported outcomes, as well as further supervision and experience in addressing the specific needs of cancer survivors when developing exercise interventions. These opportunities will support her further career development and her desire to become an independently funded investigator. The primary co-mentors are Dr. Susan Gapstur, PhD, a cancer epidemiologist and Dr. Bonnie Spring, PhD, a clinical psychologist and behavioral medicine expert. David Cella, PhD, an expert in quality of life measurement in cancer patients, Seema Khan, MD, a breast surgeon, and Kerry Courneya, PhD, an expert in developing exercise interventions with cancer survivors will serve as secondary mentors. These sponsors will guide Dr. Craft's progress; provide supervision, and support the activities outlined in her career development plan. The Robert H. Lurie Comprehensive Cancer Center and the Department of Preventive Medicine are fully committed to the time and resources required to assure Dr. Craft success in her research endeavors. A pilot randomized control trial is proposed to explore the feasibility and estimate the effectiveness of an intermittent exercise intervention, as compared to a standard exercise intervention and a usual care control group, to alleviate cancer-related symptoms (depression, pain, and fatigue) and positively impact biomarkers of metabolic function in women with early stage breast cancer who are at least six months post adjuvant treatment. A secondary exploratory aim will examine differential changes in time spent in sedentary behaviors resulting from participation in the different exercise interventions. This research is will address an important challenges facing cancer survivors, that is, identifying a lifestyle intervention to reduce cancer-related symptoms which will also benefit the survivor's physical health. RELEVANCE: This research will examine whether standard and intermittent exercise programs are effective in reducing pain, depression, and fatigue in breast cancer survivors. Further, the physical health benefits of these exercise programs for the survivor will also be studied.
描述(由申请人提供):这是NCI K 07职业发展奖的重新提交。Lynette Craft博士是一位运动机能学家,她寻求将自己的职业生涯转向癌症预防和控制。她目前的工作重点是使用运动作为临床抑郁症妇女的辅助治疗。拟议的奖项将提供必要的教育,癌症生存,行为改变的策略,患者报告的结果的评估,以及进一步的监督和经验,以解决癌症幸存者的具体需求时,制定运动干预措施。这些机会将支持她进一步的职业发展和她的愿望,成为一个独立资助的调查员。主要共同导师是癌症流行病学家Susan Gapstur博士和临床心理学家和行为医学专家Bonnie Spring博士。癌症患者生活质量测量专家大卫切拉博士、乳腺外科医生Seema Khan博士和癌症幸存者运动干预专家Kerry Courneya博士将担任二级导师。这些赞助商将指导Craft博士的进展;提供监督,并支持她的职业发展计划中概述的活动。罗伯特·H。Lurie综合癌症中心和预防医学系完全致力于确保Craft博士在研究工作中取得成功所需的时间和资源。一项初步随机对照试验旨在探索间歇性运动干预与标准运动干预和常规护理对照组相比的可行性并评估其有效性,以缓解癌症相关症状(抑郁,疼痛和疲劳)并对辅助治疗后至少6个月的早期乳腺癌女性的代谢功能生物标志物产生积极影响。第二个探索性目标将检查参与不同运动干预导致的久坐行为时间的差异变化。这项研究将解决癌症幸存者面临的一个重要挑战,即确定一种生活方式干预措施,以减少癌症相关症状,这也将有利于幸存者的身体健康。相关性:这项研究将检查标准和间歇性运动计划是否能有效减轻乳腺癌幸存者的疼痛,抑郁和疲劳。此外,还将研究这些锻炼计划对幸存者的身体健康益处。

项目成果

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会议论文数量(0)
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LYNETTE L CRAFT其他文献

LYNETTE L CRAFT的其他文献

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{{ truncateString('LYNETTE L CRAFT', 18)}}的其他基金

Intermittent Exercise and Symptom Management in Breast Cancer Survivors
乳腺癌幸存者的间歇性运动和症状管理
  • 批准号:
    8092798
  • 财政年份:
    2009
  • 资助金额:
    $ 13.01万
  • 项目类别:
Intermittent Exercise and Symptom Management in Breast Cancer Survivors
乳腺癌幸存者的间歇性运动和症状管理
  • 批准号:
    7661788
  • 财政年份:
    2009
  • 资助金额:
    $ 13.01万
  • 项目类别:

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