Arizona Cancer Center-Cancer Center Support Grant

描述（由申请人提供）：亚利桑那州癌症中心 (AZCC) 的使命是预防和治疗癌症。为了继续这一使命，本申请要求癌症中心支持补助金 (CCSG) 续签 5 年。 AZCC 最初成立于 1976 年，是亚利桑那大学 (UA) 医学院 (COM) 的一个部门。1978 年获得 CCSG，并于 1990 年被 NCI 指定为综合癌症中心。2008 年，癌症中心成为亚利桑那州健康科学中心校区的一部分，直接向负责健康事务的副教务长汇报。 为了完成我们的使命，基础、转化/临床和癌症预防和控制研究在五个项目中开展，包括癌症生物学和遗传学、癌症影像、胃肠道癌症、治疗开发和癌症预防和控制。这些程序由 12 个共享服务支持，这有助于 AZCC（整体）大于各个部分的总和。自上次更新以来，AZCC 团队仍然能够在捐助者和机构支持增加的基础上加大研究力度。尽管国家层面的可用资金减少，但我们的同行评审资金仍然保持稳定，并且我们已经获得了额外的计划项目和淋巴瘤孢子，并成功更新了我们的胃肠道癌症孢子。这些成就展示了癌症中心的跨学科活动。正如我们希望审稿人看到的那样，该团队在基础和临床科学方面取得了长足的进步。本申请中概述的更新对于我们继续努力完成我们的使命至关重要。

DESCRIPTION (provided by applicant): The mission of the Arizona Cancer Center (AZCC) is to prevent and cure cancer. To continue that mission, this application requests a 5-year renewal of the Cancer Center Support Grant (CCSG). The AZCC was founded originally as a Division of the College of Medicine (COM), University of Arizona (UA) in 1976. It obtained a CCSG in 1978 and was designated a Comprehensive Cancer Center by the NCI in 1990. In 2008, the Cancer Center became a part of the Arizona Health Sciences Center campus directly reporting to the Vice Provost for Health Affairs. To accomplish our mission, the basic and translational/clinical and cancer prevention and control research is carried out in five programs, including cancer biology and genetics, cancer imaging, gastrointestinal cancer, therapeutic development and cancer prevention and control. These programs are supported by 12 shared services, which help the AZCC (the whole) be greater than the sum of the parts. Since the last renewal, the AZCC team has still been able to increase our research efforts based on increased donor and institutional support. Our peer reviewed funding has remained stable despite decreased funding available at the national level and we have garnered additional program projects and a Lymphoma SPORE and successfully renewed our Gl cancer SPORE. Those accomplishments demonstrate the interdisciplinary activities of the Cancer Center. As we hope the reviewers will see, the team has made considerable progress in their basic and clinical science. The renewal outlined in this application is critical to keep us working to accomplish our mission.