Arizona Cancer Center-Cancer Center Support Grant

描述（由申请人提供）： 亚利桑那州癌症中心（AZCC）的使命是预防和治疗癌症。为了继续这一使命，本申请要求癌症中心支持补助金（CCSG）续期5年。AZCC最初成立于1976年，是亚利桑那大学（UA）医学院（COM）的一个部门。它于1978年获得CCSG，并于1990年被NCI指定为综合癌症中心。2008年，癌症中心成为亚利桑那州健康科学中心校园的一部分，直接向卫生事务副教务长报告。 为了完成我们的使命，我们在癌症生物学和遗传学、癌症成像、胃肠道癌症、治疗开发和癌症预防与控制等五个项目中开展了基础和转化/临床以及癌症预防与控制研究。这些程序由12个共享服务支持，这有助于AZCC（整体）大于部分之和。自上次更新以来，AZCC团队仍然能够在增加捐助者和机构支持的基础上增加我们的研究工作。尽管国家层面的资金减少，但我们的同行评审资金保持稳定，我们已经获得了额外的计划项目和淋巴瘤孢子，并成功更新了我们的GI癌症孢子。这些成就表明了癌症中心的跨学科活动。正如我们希望评审人员看到的那样，该团队在基础和临床科学方面取得了相当大的进展。本申请中概述的续约对我们继续努力完成我们的使命至关重要。

DESCRIPTION (provided by applicant): The mission of the Arizona Cancer Center (AZCC) is to prevent and cure cancer. To continue that mission, this application requests a 5-year renewal of the Cancer Center Support Grant (CCSG). The AZCC was founded originally as a Division of the College of Medicine (COM), University of Arizona (UA) in 1976. It obtained a CCSG in 1978 and was designated a Comprehensive Cancer Center by the NCI in 1990. In 2008, the Cancer Center became a part of the Arizona Health Sciences Center campus directly reporting to the Vice Provost for Health Affairs. To accomplish our mission, the basic and translational/clinical and cancer prevention and control research is carried out in five programs, including cancer biology and genetics, cancer imaging, gastrointestinal cancer, therapeutic development and cancer prevention and control. These programs are supported by 12 shared services, which help the AZCC (the whole) be greater than the sum of the parts. Since the last renewal, the AZCC team has still been able to increase our research efforts based on increased donor and institutional support. Our peer reviewed funding has remained stable despite decreased funding available at the national level and we have garnered additional program projects and a Lymphoma SPORE and successfully renewed our Gl cancer SPORE. Those accomplishments demonstrate the interdisciplinary activities of the Cancer Center. As we hope the reviewers will see, the team has made considerable progress in their basic and clinical science. The renewal outlined in this application is critical to keep us working to accomplish our mission.