Kansas IDeA Network of Biomedical Research Excellence

描述（由申请人提供）：堪萨斯大学医学中心（KUMC）在这里提出了继续支持堪萨斯IDeA生物医学研究卓越网络（K-INBRE）的申请。K-INBRE将KUMC（领导机构）与堪萨斯州其他两所主要的博士学位授予机构（堪萨斯大学劳伦斯分校，KU-L；堪萨斯州立大学，KSU）作为研究生合作机构（GPI）和七所本科合作机构（UPI）联系起来。合众国际社包括堪萨斯州的六个本科校区（恩波利亚州立大学，海斯州立大学，哈斯凯尔印第安民族大学，匹兹堡州立大学，沃什伯恩大学，威奇托州立大学）和兰斯顿大学（兰斯顿，OK）。哈斯凯尔印第安民族大学和兰斯顿大学增加了网络的多样性，第一所大学致力于教育和培训印第安人，第二所大学主要招收黑人本科生。堪萨斯州计划的长期目标是通过在目前K-INBRE的成功基础上加强该州在细胞和发育生物学方面的研究能力。K-INBRE的规模、结构和运作原则，包括强调生物医学研究的培训、网络和校际交流，以及建立一个复杂的生物信息学项目，都是在前几年的支持下建立起来的。这些目标基本保持不变，因为K-INBRE对堪萨斯州的生物医学研究产生了重大的积极影响。K-INBRE开展的项目在实现其既定目标以及NCRR IDeA项目方面取得了可衡量的成功。K-INBRE下一阶段的具体目标是：(1)通过有效的管理和关注网络，维持和改善当前细胞和发育生物学的多学科研究网络；(2)通过提供先进的生物信息学技术和教育，加强科学技术知识和整合；(3)通过双向交流基础和临床科学家培训机会，促进转化研究。在这些目标中，改善K-INBRE的新功能包括扩大研究事业的资金，改善监督和指导过程，在我们的生物信息学网络中促进综合系统生物学方法，并将转化研究的培训纳入K-INBRE目标，以使科学发现顺利进入临床领域。

DESCRIPTION (provided by applicant): The University of Kansas Medical Center (KUMC) here presents an application for continued support for the Kansas IDeA Network for Biomedical Research Excellence (K-INBRE). The K-INBRE links KUMC (Lead Institution) with the two other major doctoral-degree-granting institutions in Kansas (University of Kansas-Lawrence, KU-L; Kansas State University, KSU) as Graduate Partner Institutions (GPI) and with seven Undergraduate Partner Institutions (UPI). UPI include six Kansas undergraduate campuses (Emporia State University, Ft. Hays State University, Haskell Indian Nations University, Pittsburgh State University, Washburn University, Wichita State University) and Langston University (Langston, OK). Haskell Indian Nations University and Langston University increase diversity in the network as the first is devoted to education and training of native Americans and the second enrolls primarily black undergraduates. The long-range objective of the Kansas program is to strengthen the state's research capacity in Cell and Developmental Biology by building on the successes of the current K-INBRE. The size, structure and operational principles of the K-INBRE, which include strong emphasis on training for biomedical research, networking and intercampus communication and the establishment of a sophisticated bioinformatics program, were established during the previous years of support. These goals remain basically the same as the K-INBRE has had a major positive impact on biomedical research in the State of Kansas. Programs conducted by the K-INBRE have had measurable success in reaching their stated goals as well as those of the NCRR IDeA program. The Specific Aims proposed for the next phase of the K-INBRE are to (1) maintain and improve the current multi-disciplinary research network in Cell and Developmental Biology with efficient administration and focus on networking, (2) enhance science and technology knowledge and integration by offering sophisticated bioinformatics technology and education, (3) facilitate translational research via bidirectional exchange of basic and clinical scientist training opportunities. Within these Aims, new features that improve the K-INBRE include broadening funding for research careers together with improvements in oversight and the mentoring process, promoting an integrated systems biology approach within our bioinformatics network, and incorporating training for translational research into the K-INBRE goals so as to smooth the progress of scientific discoveries into the clinical arena. PUBLIC HEALTH RELEVANCE (provided by applicant): Research in cell and developmental biology is essential to advancing our understanding of cellular processes of health and disease. Such research relies on generation of a strong, well educated workforce, ready availability of the tools of discovery and emphasis on applying the results of discovery research to problems of human health. In building a distinguished center of research in cell and developmental biology in Kansas, the K-INBRE vigorously pursues all three of these key strategies.