Kansas IDeA Network of Biomedical Research Excellence

描述（由申请人提供）：在本申请中，堪萨斯大学医学中心（KUMC）提出了一项全面的计划，旨在提高堪萨斯研究人员有效竞争美国国立卫生研究院研究支持的能力。堪萨斯IDEA生物医学研究卓越网络（K-INBRE）包括四个主要目标。目标1是建立一个多学科研究网络，以专题科学为重点，建立、加强和整合堪萨斯州的生物医学研究。为了实现这一目标，细胞和发育生物学已被确定为一个适当的科学重点，一组四个科学合作机构[KUMC（牵头机构），堪萨斯大学劳伦斯分校，堪萨斯州立大学，威奇托州立大学]已成立，并已成立一个科学指导委员会进行指导。目标2是通过向参与机构的初级教师提供支持来建立研究基础和能力。 我们计划每年赞助四名新的细胞和发育生物学研究人员的研究，并制定强有力的职业指导和指导计划。目标3是开发一个无缝系统，以增加堪萨斯生物医学研究人员的劳动力。计划已被设计为提供特殊服务，以满足我们的六个本科外展机构的需求[恩波里亚州立大学，IFt。海斯州立大学、哈斯克尔印第安民族大学、兰斯顿大学（俄克拉荷马州兰斯顿）、匹兹堡州立大学、沃什伯恩大学]，并通过合作计划加强与科学合作伙伴机构的联系。目标4是提高堪萨斯劳动力的科学和技术知识。来自堪萨斯BRIN的支持允许在所有科学合作机构中建立生物信息学核心。的 生物信息学中心和卫星核心将继续提供有价值的分析和解释方案，并将随着所有校区DNA微阵列基因组学的建立、阵列数据存储和基于网络的访问而扩大。一个新的特点是提供管理和分析质谱数据出现的蛋白质组学和脂质组学研究。该核心将支持生物信息学教学课程的开发和获取，以及所有四个科学Parmer核心的生物信息学跨学科培训。K-INBRE计划的实施预计将促进堪萨斯州细胞和发育生物学的新力量的产生，并为改善人类健康的新战略的发展做出重要贡献。

DESCRIPTION (provided by applicant): In this application the University of Kansas Medical Center (KUMC) presents a comprehensive plan for increasing the ability of Kansas investigators to compete effectively for research support from the National Institutes of Health. The Kansas IDeA Network of Biomedical Research Excellence (K-INBRE) encompasses four major Aims. Aim 1 is to establish a multi-disciplinary research network with a thematic scientific focus that will build, strengthen and integrate biomedical research in the State of Kansas. To achieve this Aim, Cell and Developmental Biology has been identified as an appropriate scientific focus, a set of four Scientific Partner Institutions [KUMC (Lead Institution), Kansas University at Lawrence, Kansas State University, Wichita State University] has been established, and a Scientific Steering Committee has been constructed for guidance. Aim2 is to build the research base and capacity by providing support to junior faculty at the participating institutions. We plan to sponsor the research of four new investigators in Cell and Developmental Biology each year under strong career guidance and mentoring plans. Aim 3 is to develop a seamless system for increasing the workforce of biomedical researchers in Kansas. Programs have been designed to deliver special services tailored to the needs of our six undergraduate Outreach Institutions [Emporia State University, IFt. Hays State University, Haskell Indian Nations University, Langston University (Langston, OK), Pittsburg State IUniversity, Washburn University] and to strengthen their liaisons with the Scientific Partner institutions through a partnering program. Aim 4 is to enhance science and technology knowledge of the Kansas workforce. Support from the Kansas BRIN permitted the establishment of Bioinformatics cores in all of the Scientific Partner institutions. The Bioinformatics central and satellite cores will continue to offer valuable analytic and interpretative programs, and will expand with the establishment of DNA microarray genomics on all campuses, array data storage and web-based access. A new feature is the provision of management and analysis of mass spectroscopy data emerging from proteomics and lipidomics studies. This Core will support development and access to didactic coursework in Bioinformatics as well as trans-discipline training in bioinformatics at all four Scientific Parmer cores. Implementation of the K-INBRE plan is expected to facilitate the generation of new strength in Cell and Developmental Biology in the State of Kansas and to contribute importantly to the development of new strategies for improving human health.