Mississippi Functional Genomics Network

描述（由申请人提供）：最近生物医学研究中的许多飞跃都是通过使用高通量基因组学和后基因组学工具实现的。在密西西比州和整个美国，生物医学研究的持续发展需要一支在收集和分析大量数据方面受过培训的研究人员队伍。这个密西西比功能基因组网络（MFGN）项目将通过面向教师和学生的多方面方法加强该州的生物医学研究和培训。MFGN将支持和指导来自四个合作本科院校（PUIs）的8名有前途的教师研究人员，研究领域为(1)癌症功能基因组学和(2)微生物发病机制功能基因组学；两者都对人类健康至关重要。经验丰富的科学家导师将与每位PUI研究员密切互动，以促进独立研究项目的发展，并加强这些学院的本科生培训。其他培训和指导活动将包括一系列生物信息学讲习班、拨款写作/管理讲习班、出版/演示讲习班、研究设施讲习班和研究研讨会。五个核心研究设施将为该州的研究人员提供高通量基因组学、蛋白质组学、细胞组学和成像仪器。推广工作将包括夏季研究奖励，以资助本科生在该州已建立的生物医学研究实验室进行实践研究，一系列杰出科学家研讨会和职业发展讲习班。可从MFGN网页（mfgn.usm.edu/mfgn）访问的MFGN生物信息学核心将通过增加额外的生物信息学分析软件和在线培训工具来扩展和增强。还将在MFGN网站上提供资助机会的在线信息交换中心和电子图书馆，供该州的学生和教师使用。科学网络、指导、培训和推广活动、生物信息学培训和工具以及核心研究设施将对密西西比州当前和未来生物医学研究人员的研究和培训产生强烈影响。

DESCRIPTION (provided by applicant): Many of the recent leaps forward in biomedical research were made possible by the use of high-throughput genomics and post-genomics tools. The continued advancement of biomedical research in Mississippi and in the United States as a whole demands a workforce of researchers trained in collection and analysis of massive amounts of data. This Mississippi Functional Genomic Network (MFGN) project will strengthen biomedical research and training in the State by a multi-faceted approach directed toward both faculty and students. MFGN will support and mentor eight promising faculty researchers, located at four Partner Undergraduate Institutions (PUIs), in the areas of (1) Functional Genomics of Cancer and (2) Functional Genomics of Microbial Pathogenesis; both of vital importance to human health. Experienced scientist mentors will interact closely with each PUI researcher to facilitate development of independent research projects and enhance undergraduate training at these colleges. Additional training and mentoring activities will include a series of bioinformatics workshops, grant writing/management workshops, publication/presentation workshops, research facility workshops, and research seminars. Five core research facilities will make high-throughput genomics, proteomics, cellomics and imaging instrumentation available to researchers in the State. Outreach efforts will include summer research awards to fund undergraduate students to experience hands-on research in established biomedical research laboratories in the State, a series of Distinguished Scientist Seminars and career development workshops. The MFGN Bioinformatics Core, accessible from the MFGN web page (mfgn.usm.edu/mfgn), will be expanded and enhanced by adding additional bioinformatics analysis software and online training tools. An online clearinghouse for funding opportunities and e-library will also be available on the MFGN web site for use by students and faculty in the State. The scientific network, mentoring, training and outreach activities, bioinformatics training and tools and core research facilities will have a strong impact on research and training of both current and future biomedical researchers in Mississippi.