ACTIVITY 1: BIOMEDICAL IMAGING AND BIOENGINEERING

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 磁共振（MR）图像处理核心的总体目标是提供图像处理支持，基础设施改进和方法开发，以补充和充分利用快速扩展的MR研究设施，支持一系列临床研究。MR研究设施位于女王医学中心校园内，是夏威夷大学和女王医学中心的共同努力。MR研究机构围绕Siemens 3 Tesla MR扫描仪构建。MR图像处理核心的具体目标包括四个主要领域：1）通过图像处理支持分析MR扫描，以及开发和分析试点研究的研究支持; 2）基础设施开发，包括MR扫描仪的升级，本地处理和数据存储计算机的安装，改进的互联网连接，以及优化图像处理流的改进; 3）方法学改进，以开发和验证用于临床研究的图像处理工具;以及4）对MR研究机构的教师用户和工作人员进行图像处理培训。MR图像处理核心的服务将允许更快地公布研究结果，并导致更好地评估药物滥用和慢性疾病对大脑的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall goal of the Magnetic Resonance (MR) Image-Processing Core is to provide image-processing support, infrastructure improvements and methodological developments to complement and fully utilize a rapidly expanding MR Research Facility that supports an array of clinical research studies. The MR Research Facility, located on The Queen's Medical Center campus, is a joint effort of the University of Hawaii and The Queen's Medical Center. The MR Research Facility is built around a Siemens 3 Tesla MR scanner. The specific aims of the MR Image-Processing Core cover four main areas: 1) research support through image-processing support for analyzing MR scans, and development and analysis of pilot studies; 2) infrastructure development involving upgrades to the MR scanner, installation of local processing and data storage computers, improved internet connectivity, and improvements to optimize image processing streams; 3) methodological improvements to develop and validate image-processing tools for clinical research; and 4) training of MR Research Facility faculty users and staff in image processing. The services of the MR Image-Processing Core will permit more rapid publication of research results and lead to improved evaluation of the effects of drug abuse and chronic diseases on the brain.