New England Primate Research Center Base Grant

新英格兰灵长类研究中心基础拨款

• 批准号: 7912043
• 负责人: Jeffrey S Flier
• 金额: $ 57.79万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-17 至 2012-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7912043
• 关键词: New; England; Primate; Research; Center

This renewal application requests five years of funding for continuation of the multidisciplinary biomedical research and resource program at the New England Primate Research Center (NEPRC). Detailed plans are presented for the support of meritorious research which will contribute to the understanding and solution of human health problems using nonhuman primates, as mandated by NIH. We describe the research programs, collaborative activities, core services, and pilot research programs within seven scientific units at NEPRC: Behavioral Biology, Comparative Pathology, Immunology, Microbiology, Neurochemistry, Primate Resources, and Tumor Virology. The research activities and core services within these seven units are intently focused on major public health challenges, principally AIDS treatment and prevention, viral-induced cancer, neurodegenerative diseases, and drug addiction. The nature of the research program is fundamentally basic in some cases, applied in others. The research programs and support services are also highly collaborative in nature, usually involving contributions from multiple scientific units from within and outside NEPRC. The core and service activities funded by NEPRC?s base grant are currently supporting$10.1 million in NIH-funded research to intramural NEPRC investigators and $268 million in NIH-funded research to extramural nonNEPRC investigators. Additionally, this proposal seeks to (1) enhance the Center?s ability to serve as a regional, national and international resource for collaborative, affiliated and visiting scientists by providing specialized facilities, equipment and technological expertise, (2) enhance the availability of non-human primates for use in biomedical research, (3) train young investigators, and (4) provide the administrative, scientific and primate resources infrastructure necessary to maintain and operate a Center. Also included in this application is a five year Modernization Program. The New England Primate Research Center, Harvard Medical School, is fully accredited by AAALAC International.

该更新申请要求在新英格兰灵长类动物研究中心（NEPRC）的多学科生物医学研究和资源计划中延续五年的资金。提出了详细的计划，以支持有罪研究，这将有助于理解和解决人类健康问题 按照NIH的要求，使用非人类灵长类动物。我们描述研究计划，协作 NEPRC的七个科学单位内的活动，核心服务和试点研究计划：行为 生物学，比较病理学，免疫学，微生物学，神经化学，灵长类动物资源和 肿瘤病毒学。这七个单元内的研究活动和核心服务是专注于专注的 关于主要的公共卫生挑战，主要是艾滋病治疗和预防，病毒引起的癌症， 神经退行性疾病和药物成瘾。研究计划的性质从根本上是 在某些情况下，基本在其他情况下应用。研究计划和支持服务也很高 本质上的协作，通常涉及来自内部多个科学单位的贡献 在Neprc外面。 NEPRC的基础赠款目前是由NEPRC资助的核心和服务活动 为NIH资助的1010万美元提供给NEPRC内部调查人员的研究和2.68亿美元 NIH资助的研究对壁外非NEPRC研究人员。此外，该提案试图（1） 增强中心的能力，成为区域，国家和国际合作资源的能力， 通过提供专业设施，设备和技术来隶属和来访科学家 专业知识，（2）增强非人类灵长类动物用于生物医学研究的可用性，（3）火车 年轻的研究人员和（4）提供行政，科学和灵长类动物资源基础设施 维护和操作中心所必需的。此申请中还包括五年 现代化计划。哈佛医学院的新英格兰灵长类动物研究中心完全 被AAAALAC国际的认可。