Experimental Mice
Experimental Mice
批准号:
7944527
负责人:
THOMAS DOETSCHMAN
金额:
$19.69万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-08-19 至 2014-06-30
关键词:
AmericanAnimal HousingAnimal WelfareAnimal Welfare ActAnimalsArizonaArtsBiometryBlood specimenBreathingBreedingCancer CenterCancer Center Support GrantCancer cell lineCarbon DioxideCellsCertificationChemopreventive AgentClinical TrialsCommittee MembersCommunitiesCryopreservationData CollectionDevelopmentDietEmbryoEnsureEuthanasiaExperimental DesignsFatty acid glycerol estersFundingGasesGene TargetingGenetic EngineeringGenetically Engineered MouseGrowthHealth SciencesHourHousingHuman ResourcesIACUCInjection of therapeutic agentKnock-outLaboratory AnimalsLaboratory ResearchLifeMailsMaintenanceMalignant NeoplasmsMammary glandMedicalMethodsModelingMouse StrainsMusMycoplasmaOralPerformancePoliciesProceduresProductionProtocols documentationPublic HealthPuncture procedureQuality ControlRecommendationRegulationReportingResearchResearch PersonnelSCID MiceScientistScreening procedureServicesSpecialistSystemTailTechnical ExpertiseTechniquesTechnologyTherapeuticTrainingTransfectionTransgenic MiceTransgenic OrganismsUniversitiesUpdateVeinsVeterinariansWorkWritingXenograft procedureanimal careanimal facilityauthoritycomparativecomputerizedcostdesigndesign and constructionembryonic stem cellexperiencehuman cancer mouse modelin vivolecturesmembermouse modelpathogenprogramsresearch facilityresearch studysquare footvector
中文摘要
9.1.3实验小鼠共享服务
英文摘要
9.1.3 EXPERIMENTAL MOUSE SHARED SERVICE
The Experimental Mouse Shared Service (EMSS) is a one-stop shared service for all your in vivo mouse
experimentation needs. The purpose of the EMSS is to provide investigators at the Arizona Cancer Center
(AZCC) with experimental mouse models and with a wide range of mouse experimentation techniques. The
EMSS has combined the previous Genetically Engineered Mouse "Developmental" Shared Service (GEMSS)
and the previous EMSS. Therefore, the EMSS begins with the design and construction of gene targeting and
transgenic mouse vectors, gene targeting and ES cell screening for targeted Clones, production of genetargeted
mice, production of transgenic mice, screening for transgenic and knockout founders, embryo
rederivation for pathogen cleanup and cryopreservation of mouse strains through to complete experimentation
services in all aspects of xenograft and GEM models. The specific objectives of the EMSS include creation of
models, maintenance of shared and investigator colonies, assistance in the design of in vivo experiments, and
performance of mouse experiments by personnel with expertise in mouse experimental protocols. Hence, the
EMSS provides consistency and quality of procedures within and between mouse experiments that ensures
accuracy in experimental results, confidence in interpretation of results, and an inner-consistency between
mouse experiments which is essential for intra-lab and inter-lab comparative analyses. Due to the fact that the
mouse is a model for all translational cancer work for both NIH-type funding as well as progression to clinical
trials, the EMSS is an absolutely essential shared service. The benefits of the EMSS are to provide AZCC
investigators with a cost-effective mechanism for the creation of different mouse models and for completing in
vivo mouse experiments utilizing highly trained and experienced technicians. The EMSS continues to expand
its services in a very cost-effective and efficient manner.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Cell-specific analysis of transcription and epigenomic status in PDAC
-
批准号:8468670
-
项目类别:
-
资助金额:$18.58万
-
财政年份:2012
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Cell-specific analysis of transcription and epigenomic status in PDAC
-
批准号:8227178
-
项目类别:
-
资助金额:$16.48万
-
财政年份:2012
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Transforming Growth Factor beta in T-Cell Homeostasis and Tolerance
-
批准号:7197991
-
项目类别:
-
资助金额:$36.4万
-
财政年份:2006
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Transforming Growth Factor beta in T-Cell Homeostasis and Tolerance
-
批准号:7492844
-
项目类别:
-
资助金额:$35.49万
-
财政年份:2006
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Transforming Growth Factor beta in T-Cell Homeostasis and Tolerance
-
批准号:7023314
-
项目类别:
-
资助金额:$38.37万
-
财政年份:2006
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Transforming Growth Factor beta in T-Cell Homeostasis and Tolerance
-
批准号:7759458
-
项目类别:
-
资助金额:$36.55万
-
财政年份:2006
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Transforming Growth Factor beta in T-Cell Homeostasis and Tolerance
-
批准号:7775091
-
项目类别:
-
资助金额:$37.27万
-
财政年份:2006
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Roles of FGF2 and TGFbeta in cardiac hypertrophy
-
批准号:6623478
-
项目类别:
-
资助金额:$37.92万
-
财政年份:2002
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Roles of FGF2 and TGFbeta in cardiac hypertrophy
-
批准号:6729931
-
项目类别:
-
资助金额:$37.91万
-
财政年份:2002
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Roles of FGF2 and TGFbeta in cardiac hypertrophy
-
批准号:6466184
-
项目类别:
-
资助金额:$37.94万
-
财政年份:2002
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Core--Mouse Polymorphism Facility
-
批准号:6579909
-
项目类别:
-
资助金额:$19.7万
-
财政年份:2002
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Core--Mouse Modeling
-
批准号:6579908
-
项目类别:
-
资助金额:$19.7万
-
财政年份:2002
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Roles of FGF2 and TGFbeta in cardiac hypertrophy
-
批准号:6865395
-
项目类别:
-
资助金额:$37.89万
-
财政年份:2002
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Core--Mouse Modeling
-
批准号:6617326
-
项目类别:
-
资助金额:$19.7万
-
财政年份:2002
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Core--Mouse Polymorphism Facility
-
批准号:6618908
-
项目类别:
-
资助金额:$19.7万
-
财政年份:2002
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Core--Mouse Polymorphism Facility
-
批准号:6617327
-
项目类别:
-
资助金额:$19.7万
-
财政年份:2002
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
Core--Mouse Modeling
-
批准号:6618907
-
项目类别:
-
资助金额:$19.7万
-
财政年份:2002
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
CORE--MOUSE FACILITY
-
批准号:6346153
-
项目类别:
-
资助金额:$13.47万
-
财政年份:2000
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
TUMOR SUPPRESSOR HETEROZYGOTES AS GENOTOXICANT REPORTERS
-
批准号:6346150
-
项目类别:
-
资助金额:$13.47万
-
财政年份:2000
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
ANIMAL MODELS FOR CARDIOVASCULAR DISEASE
-
批准号:6202280
-
项目类别:
-
资助金额:$20.67万
-
财政年份:1999
-
负责人:THOMAS DOETSCHMAN
-
依托单位:
海外基金