STRUCTURAL MAPPING OF CD134 BINDING RECEPTOR FOR BINDING OF FIV
STRUCTURAL MAPPING OF CD134 BINDING RECEPTOR FOR BINDING OF FIV
批准号:
7955255
负责人:
John H Elder
金额:
$2.43万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-05-01 至 2010-04-30
关键词:
BindingBiomedical ComputingCD4 Positive T LymphocytesCXCR4 geneComputer Retrieval of Information on Scientific Projects DatabaseFamily FelidaeFeline Immunodeficiency VirusFundingGrantHumanInfectionInstitutionMapsResearchResearch PersonnelResourcesSourceSpecificityUnited States National Institutes of HealthVirusVirus Diseasesreceptor binding
中文摘要
该子项目是利用
由NIH/NCRR资助的中心赠款提供的资源。子项目和
研究者(PI)可能从另一个NIH来源获得主要资金,
因此可以在其他CRISP条目中表示。列出的机构是
中心,不一定是研究者的机构。
CD 134是猫免疫缺陷病毒(FIV)的主要结合受体,并且与CXCR 4一起促进CD 4 + T细胞的感染。
细胞人CD 134不能支持FIV感染。为了描述对确定病毒特异性的重要区域,
CD 134,我们交换了人和猫CD 134之间的结构域。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
CD134 is a primary binding receptor for feline immunodeficiency virus (FIV), and with CXCR4 facilitates infection of CD4+ T
cells. Human CD134 fails to support FIV infection. To delineate the regions important for defining virus specificity of
CD134, we exchanged domains between human and feline CD134.
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会议论文
Humoral response to viral and self-antigens in HIV infection
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批准号:8602680
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项目类别:
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资助金额:$26.72万
-
财政年份:2013
-
负责人:John H Elder
-
依托单位:
Humoral response to viral and self-antigens in HIV infection
-
批准号:8664345
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项目类别:
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资助金额:$23.69万
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财政年份:2013
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负责人:John H Elder
-
依托单位:
MOLECULAR ANALYSIS OF FIV
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批准号:8171269
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项目类别:
-
资助金额:$0.24万
-
财政年份:2010
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负责人:John H Elder
-
依托单位:
QUESTION OR TRAINING REQUEST FOR THE YEAST RESOURCE CENTER
-
批准号:7957850
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项目类别:
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资助金额:$0.48万
-
财政年份:2009
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负责人:John H Elder
-
依托单位:
Structural basis for drug resistance in HIV and FIV PRs
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批准号:7860457
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项目类别:
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资助金额:$47.48万
-
财政年份:2009
-
负责人:John H Elder
-
依托单位:
MOLECULAR ANALYSIS OF FIV
-
批准号:7957859
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项目类别:
-
资助金额:$0.33万
-
财政年份:2009
-
负责人:John H Elder
-
依托单位:
Structural basis for drug resistance in HIV and FIV PRs
-
批准号:7756707
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项目类别:
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资助金额:$47.48万
-
财政年份:2009
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负责人:John H Elder
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依托单位:
Protein Production, Analysis and Assay Development
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批准号:7434199
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项目类别:
-
资助金额:$31.57万
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财政年份:2008
-
负责人:John H Elder
-
依托单位:
STRUCTURAL MAPPING OF CD134 BINDING RECEPTOR FOR BINDING OF FIV
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批准号:7722362
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项目类别:
-
资助金额:$0.34万
-
财政年份:2008
-
负责人:John H Elder
-
依托单位:
STRUCTURAL MAPPING OF CD134 BINDING RECEPTOR FOR BINDING OF FIV
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批准号:7601709
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项目类别:
-
资助金额:$0.76万
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财政年份:2007
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负责人:John H Elder
-
依托单位:
STRUCTURAL MAPPING OF CD134 BINDING RECEPTOR FOR BINDING OF FIV
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批准号:7358725
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项目类别:
-
资助金额:$1.28万
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财政年份:2006
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负责人:John H Elder
-
依托单位:
Virology of the Central Nervous System
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批准号:6531135
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项目类别:
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资助金额:$27.29万
-
财政年份:2001
-
负责人:John H Elder
-
依托单位:
Virology of the Central Nervous System
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批准号:6919885
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项目类别:
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资助金额:$31.38万
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财政年份:2001
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负责人:John H Elder
-
依托单位:
Virology of the Central Nervous System
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批准号:7848083
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项目类别:
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资助金额:$18.61万
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财政年份:2001
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负责人:John H Elder
-
依托单位:
CAT/MOUSE MODELS TO EVALUATE PR-TARGETED ANTIVIRALS
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批准号:6313498
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项目类别:
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资助金额:$39.89万
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财政年份:2001
-
负责人:John H Elder
-
依托单位:
Virology of the Central Nervous System
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批准号:7638554
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项目类别:
-
资助金额:$21.79万
-
财政年份:2001
-
负责人:John H Elder
-
依托单位:
Virology of the Central Nervous System
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批准号:6612633
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项目类别:
-
资助金额:$31.17万
-
财政年份:2001
-
负责人:John H Elder
-
依托单位:
Virology of the Central Nervous System
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批准号:6314522
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项目类别:
-
资助金额:$24.74万
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财政年份:2001
-
负责人:John H Elder
-
依托单位:
Virology of the Central Nervous System
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批准号:7067731
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项目类别:
-
资助金额:$14.5万
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财政年份:2001
-
负责人:John H Elder
-
依托单位:
Virology of the Central Nervous System
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批准号:7252620
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项目类别:
-
资助金额:$20.11万
-
财政年份:2001
-
负责人:John H Elder
-
依托单位:
海外基金