Cell Morphology and Pathology Core

细胞形态学和病理学核心

• 批准号: 7688344
• 负责人: PAUL B MCCRAY
• 金额: $ 16.88万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7688344
• 关键词: Animal Disease Models; Animal Model; Antibodies; Cell Culture Techniques; Cells; Cellular Morphology; Confocal Microscopy; Consultations; Cryopreservation; Cystic Fibrosis; Detection; Development; Disease; Economics; Electron Microscopy; Equipment; Fluorescence; Galactosidase; Gene Transfer; Goals; Hereditary Disease; Image Analysis; In Situ Hybridization; Instruction; Label; Methods; Microscopic; Microscopy; Other Genetics; Paraffin; Pathology; Plastic Embedding; Preparation; Process; Proteins; Reporter; Research Personnel; Scientist; Services; Specimen; Staining method; Stains; Techniques; Therapeutic Studies; Tissue Fixation; Tissues; Veterinary Pathology; computerized; experience; gene therapy; human disease; interest; meetings; micrography; response; tissue preparation; tool

Cell Morphology and Pathology Core: The goals of the Cell Morphology and Pathology Core are to provide services and instruction to investigators of the Gene Therapy Center and to new investigators interested in developing gene transfer approaches to cystic fibrosis (CF) and other genetic diseases. We strive to provide expert assistance in the interpretation of disease pathology as investigators use gene transfer tools in new large and small animal models of human disease. To facilitate these goals the Core provides: 1) technical assistance for labor- intensive techniques such as the preparation of sections from tissue or cell cultures, 2) ready access to equipment, 3) economic benefits through centralization of equipment and facilities, and 4) consultation and instruction in specialized morphologic techniques and methods of image analysis. These goals are met through oversight by the Core Director, an established CF scientist with experience in a variety of microscopy techniques that are useful in gene therapy research.

细胞形态学和病理学核心： 细胞形态学和病理学核心的目标是为研究人员提供服务和指导 基因治疗中心和对开发基因转移方法感兴趣的新研究人员， 囊性纤维化（CF）和其他遗传性疾病。我们致力于为您提供专业的口译服务， 疾病病理学作为研究人员使用基因转移工具在新的大型和小型动物模型的人类 疾病为了促进这些目标的实现，核心提供：1）劳动密集型技术的技术援助 例如从组织或细胞培养物制备切片，2）容易获得设备，3）经济 通过集中设备和设施的好处，以及4）专业咨询和指导 形态学技术和图像分析方法。这些目标是通过核心小组的监督实现的 主任，一位资深的CF科学家，在各种显微镜技术方面具有丰富的经验， 基因治疗研究。