Biological Inquiry into the Mechanisms and Neuroprotective Strategy for TBI

TBI 机制和神经保护策略的生物学探究

• 批准号: 7748031
• 负责人: Dong Feng Chen
• 金额: --
• 依托单位: VA BOSTON HEALTH CARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2012-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7748031
• 关键词: Accounting; Acute; Affect; Area; Axon; Behavior; Biochemical; Biological; Biological Assay; Blast Cell; Brain; Brain Injuries; CCL2 gene; Cell Survival; Cessation of life; Chronic; Chronic Headaches; Clinical; Closed head injuries; Craniocerebral Trauma; Crush Injury; Diagnosis; Diffuse; Diffuse Axonal Injury; Down-Regulation; Emergency Situation; Event; Eye; Failure; Functional disorder; Future; Gene Mutation; Genetic; Genetically Engineered Mouse; Health; Hour; Immunohistochemistry; Inflammatory; Injury; Knockout Mice; Knowledge; Laboratories; Length; Location; Medical; Military Personnel; Modeling; Molecular; Mood Disorders; Mouse Strains; Mus; Natural regeneration; Nerve Crush; Nerve Fibers; Nerve Regeneration; Neurocognitive Deficit; Neurons; Optic Nerve; Optic Nerve Injuries; Outcome; Pathologic; Pathology; Patients; Peripheral; Pharmaceutical Preparations; Pharmacotherapy; Population; Protocols documentation; Recovery of Function; Recruitment Activity; Research; Research Project Grants; Retinal; Retinal Ganglion Cells; Risk; Role; Secondary to; Signal Transduction; Simulate; Staging; Staining method; Stains; System; Time; Translations; Trauma; Traumatic Brain Injury; Traumatic CNS injury; Veterans; Work; abstracting; axon regeneration; cellular pathology; clinical practice; combat; cytokine; disability; efficacy testing; experience; genetic technology; improved; in vivo; injured; innovation; innovative technologies; loss of function; macrophage; mouse model; neuroinflammation; neuron loss; novel; optic nerve regeneration; outcome forecast; postnatal; regenerative; repaired; research study; response; tool; treatment strategy; trend; visual information; white matter