Training Clinical Veterinarians in Nonhuman Primate Clinical Medicine

描述（由申请人提供）：NCRR认识到，在生物医学研究中使用的圈养非人灵长类动物的临床管理方面训练有素并精通的兽医日益短缺。我们在此请求资金支持三位dvm后住院医师进行为期两年的灵长类医学培训。维克森林大学医学院（WFUSM）和比较医学部门在使用人类疾病的NHP模型以及在实验动物和比较医学方面培训兽医方面有50年的历史。培训的重点是发展管理、医学、病理学和在生物医学研究中使用国家卫生保健计划方面的专门知识。实验动物和比较医学培训研究培训补助金（MR Adams，现任PI）是由ncrr支持的T32补助金连续资助的第48个年头。此外，WFUSM目前在实验动物医学和诊断病理学方面支持dvm的住院医师培训。因此，这里提出的培训是对现有方案的补充，而不是取代。有16名培训教员，都有比较医学方面的任命，其中14名是临床医学博士，4名是ACLAM文凭，2名是ACVP文凭。受训者将选择一名DVM导师，他也可以作为顾问，在一个有限范围的临床研究项目中进行，作为他们培训的一部分。作为导师或共同导师，所有学员都将获得ACLAM文凭。培训课程包括医学灵长类学、生物医学研究中的动物模型、灵长类动物行为和心理健康。还包括灵长类临床医学和诊断病理学的轮转；以经验为基础的IACUC培训；以及非人类灵长类动物研究资源群体管理的短期课程：SPF和遗传考虑，动物设施的成本核算和职业健康。学员还将参加每周的期刊俱乐部、临床大查房和比较病理学会议。最后，西南生物医学研究基金会（获得狒狒的经验和非人类灵长类动物种群遗传管理的短期课程）和巴斯特罗普M.D.安德森癌症研究中心（获得黑猩猩和新热带灵长类动物的经验）的实习也包括在内。

DESCRIPTION (provided by applicant): The NCRR recognizes a growing shortage of veterinarians trained and proficient in the clinical management of captive nonhuman primates used in biomedical research. We request here funding to support three post-DVM residents for two years of training in primate medicine. The Wake Forest University School of Medicine (WFUSM) and the Section of Comparative Medicine have a 50-year history in the use of NHP models of human disease and in the training of veterinarians in laboratory animal and comparative medicine. This training has focused on development of expertise in the management, medicine, pathology and use of NHPs in biomedical research. The research training grant Laboratory Animal and Comparative Medicine Training (MR Adams, current PI) is in its 48th year of continuous funding by and NCRR-supported T32 grant. In addition, WFUSM currently supports residency training of DVMs in laboratory animal medicine and diagnostic pathology. Thus, the training proposed here complements, but does not replace, existing programs. There are 16 members of the training faculty, all have appointments in Comparative Medicine, 14 of these are DVMs, 4 are ACLAM diplomates and 2 are ACVP diplomates. Trainees will choose a DVM mentor, who may also serve as advisor on a limited-scope clinical research project to be conducted as part of their training. All trainees will have an ACLAM diplomate as a mentor or co-mentor. Training will include courses in Medical Primatology, Animal Models in Biomedical Research, and Primate Behavior and Psychological Wellbeing. Also included are rotations in primate clinical medicine and diagnostic pathology; experience-based IACUC training; and short courses in The Management of Nonhuman Primate Research Resource Colonies: SPF and Genetic Considerations, Cost Accounting for Animal Facilities, and Occupational Health. Trainees will also participate in weekly Journal Clubs, Clinical Grand Rounds and the Comparative Pathology Conference. Finally, externships to the Southwest Foundation for Biomedical Research (for experience with baboons and a short course in genetic management of nonhuman primate colonies) and M.D. Anderson Cancer Research Center at Bastrop (for experience with chimpanzees and neotropical primates) are also included.