Antiretroviral Pharmacology Training in Resource Poor Countries

描述(由申请者提供)：这是AITRP关于布法罗大学(UB)和津巴布韦大学(UZ)之间的研究生培训倡议的修订提案，重点是艾滋病毒/艾滋病临床药理学。这两个机构的项目教员都是经验丰富的研究人员，他们将为UZ的学生提供指导培训，这些学生将为多学科团队提供临床药理学专业知识，以实现津巴布韦的艾滋病毒/艾滋病研究目标。该计划是为AITRP学员设计的，旨在通过与具有已建立的临床/翻译和实验室研究环境的教师和卫生专业人员的指导互动而受益。AITRP的基础设施已经扩大，包括与NIAID资助的津巴布韦国际多学科研究网络的正式合作，通过UZ临床试验网站进行协调，以及其他美国支持和津巴布韦的研究项目。这种方法将为AITRP受训人员提供机会，在AITRP期间发展他们的研究事业，然后在培训期结束后继续在协作和指导的环境中继续工作。这一修订的申请包括为研究生实习生提供的重点教学课程，以及包括在亚利桑那大学和亚利桑那大学进行现场培训的综合研究项目体验。AITRP将专注于一群训练有素的个人，他们将在UZ现有的多学科环境中继续他们的研究项目，并持续提供指导和职业发展。UZ的教职员工和行政领导认识到有必要支持未来研究人员的发展，以应对津巴布韦的艾滋病毒/艾滋病流行病，这表明对拟议的AITRP提供了强有力的机构支持。与公共卫生的相关性：由于艾滋病毒/艾滋病流行病继续影响发展中国家，艾滋病毒/艾滋病临床药理学培训的需要也扩大了。我们的AITRP通过提供多学科培训机制来满足这些需求，以进行艾滋病毒/艾滋病治疗研究，并实现津巴布韦为优化抗逆转录病毒治疗和扩大临床医生科学家队伍而制定的目标。

DESCRIPTION (provided by applicant): This is a revised AITRP proposal for a postgraduate training initiative with an emphasis on HIV/AIDS clinical pharmacology between the University at Buffalo (UB) and the University of Zimbabwe (UZ). The program faculty at both institutions are experienced investigators that will contribute mentored training to UZ students who, in turn, will contribute clinical pharmacology expertise to multidisciplinary teams to achieve the HIV/AIDS research goals for Zimbabwe. The program is designed for AITRP trainees to benefit from mentored interactions with faculty and health professionals with established clinical/translational and laboratory research environments. The AITRP infrastructure has been broadened to include formalized collaboration with NIAID-funded international, multidisciplinary research networks in Zimbabwe, coordinated through the UZ Clinical Trials Site, as well as other US-supported and Zimbabwe-based research programs. This approach will provide opportunities for AITRP trainees to develop their research career during the AITRP and then continue in a collaborative, mentored environment after the training period. This revised application includes a focused didactic curriculum for postgraduate trainees and an integrated research project experience that includes on-site training at UB and UZ. The AITRP will focus on a group of highly trained individuals who will then pursue their research programs within the multidisciplinary environment that is present at UZ with continued mentoring and career development. Strong institutional support for the proposed AITRP is evident through participation of faculty and administrative leaders at UZ in recognition of the need to support the development of future researchers to address the HIV/AIDS epidemic in Zimbabwe. PUBLIC HEALTH RELEVANCE: As the HIV/AIDS epidemic has continued to impact on developing countries, the need for training in HIV/AIDS clinical Pharmacology has also expanded in scope. Our AITRP meets these needs by providing a mechanism for multi-disciplinary training to conduct HIV/AIDS treatment research and achieve the goals that Zimbabwe has established for optimizing antiretroviral therapy and expanding its pool of clinician scientists.