Antiretroviral Pharmacology Training in Resource Poor Countries

描述（由申请人提供）：这是一个修订后的AITRP建议的研究生培训计划，重点是在布法罗大学（UB）和津巴布韦大学（UZ）之间的艾滋病毒/艾滋病临床药理学。这两个机构的计划教师都是经验丰富的研究人员，他们将为UZ学生提供指导培训，反过来，他们将为多学科团队提供临床药理学专业知识，以实现津巴布韦的艾滋病毒/艾滋病研究目标。该计划是专为AITRP学员受益于导师与教师和卫生专业人员与建立临床/翻译和实验室研究环境的互动。AITRP的基础设施已经扩大到包括与NIAID资助的国际合作，津巴布韦的多学科研究网络，通过UZ临床试验网站以及其他美国支持和津巴布韦的研究计划进行协调。这种方法将为AITRP学员提供机会，在AITRP期间发展他们的研究生涯，然后在培训期结束后继续在协作，指导的环境中。这个修订后的应用程序包括研究生学员的重点教学课程和综合研究项目的经验，包括在UB和UZ的现场培训。AITRP将专注于一群训练有素的个人，他们将在UZ的多学科环境中继续进行他们的研究计划，并继续进行指导和职业发展。对拟议的AITRP的强有力的机构支持是显而易见的，通过在UZ的教师和行政领导人的参与，认识到需要支持未来的研究人员的发展，以解决艾滋病毒/艾滋病在津巴布韦的流行。公共卫生相关性：由于艾滋病毒/艾滋病的流行继续影响发展中国家，对艾滋病毒/艾滋病临床药理学培训的需求范围也扩大了。我们的AITRP通过提供多学科培训机制来满足这些需求，以进行艾滋病毒/艾滋病治疗研究，并实现津巴布韦为优化抗逆转录病毒疗法和扩大临床科学家人才库而制定的目标。

DESCRIPTION (provided by applicant): This is a revised AITRP proposal for a postgraduate training initiative with an emphasis on HIV/AIDS clinical pharmacology between the University at Buffalo (UB) and the University of Zimbabwe (UZ). The program faculty at both institutions are experienced investigators that will contribute mentored training to UZ students who, in turn, will contribute clinical pharmacology expertise to multidisciplinary teams to achieve the HIV/AIDS research goals for Zimbabwe. The program is designed for AITRP trainees to benefit from mentored interactions with faculty and health professionals with established clinical/translational and laboratory research environments. The AITRP infrastructure has been broadened to include formalized collaboration with NIAID-funded international, multidisciplinary research networks in Zimbabwe, coordinated through the UZ Clinical Trials Site, as well as other US-supported and Zimbabwe-based research programs. This approach will provide opportunities for AITRP trainees to develop their research career during the AITRP and then continue in a collaborative, mentored environment after the training period. This revised application includes a focused didactic curriculum for postgraduate trainees and an integrated research project experience that includes on-site training at UB and UZ. The AITRP will focus on a group of highly trained individuals who will then pursue their research programs within the multidisciplinary environment that is present at UZ with continued mentoring and career development. Strong institutional support for the proposed AITRP is evident through participation of faculty and administrative leaders at UZ in recognition of the need to support the development of future researchers to address the HIV/AIDS epidemic in Zimbabwe. PUBLIC HEALTH RELEVANCE: As the HIV/AIDS epidemic has continued to impact on developing countries, the need for training in HIV/AIDS clinical Pharmacology has also expanded in scope. Our AITRP meets these needs by providing a mechanism for multi-disciplinary training to conduct HIV/AIDS treatment research and achieve the goals that Zimbabwe has established for optimizing antiretroviral therapy and expanding its pool of clinician scientists.