Antiretroviral Pharmacology Training in Resource Poor Countries

资源匮乏国家的抗逆转录病毒药理学培训

• 批准号: 7680562
• 负责人: Gene D. Morse
• 金额: $ 30.01万
• 依托单位: STATE UNIVERSITY OF NEW YORK AT BUFFALO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-08 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7680562
• 关键词: AIDS Treatment Research; AIDS/HIV problem; Address; Anti-Retroviral Agents; Buffaloes; Clinical; Clinical Pharmacology; Clinical Trials; Collaborations; Country; Developed Countries; Developing Countries; Development; Educational Curriculum; Environment; Epidemic; Faculty; Funding; Future; Goals; Health Professional; Individual; Institution; Interdisciplinary Study; International; Laboratory Research; Mentors; Pharmacology; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Scientist; Site; Students; Training; Universities; Zimbabwe; antiretroviral therapy; base; career; career development; design; experience; meetings; multidisciplinary; programs; public health relevance

DESCRIPTION (provided by applicant): This is a revised AITRP proposal for a postgraduate training initiative with an emphasis on HIV/AIDS clinical pharmacology between the University at Buffalo (UB) and the University of Zimbabwe (UZ). The program faculty at both institutions are experienced investigators that will contribute mentored training to UZ students who, in turn, will contribute clinical pharmacology expertise to multidisciplinary teams to achieve the HIV/AIDS research goals for Zimbabwe. The program is designed for AITRP trainees to benefit from mentored interactions with faculty and health professionals with established clinical/translational and laboratory research environments. The AITRP infrastructure has been broadened to include formalized collaboration with NIAID-funded international, multidisciplinary research networks in Zimbabwe, coordinated through the UZ Clinical Trials Site, as well as other US-supported and Zimbabwe-based research programs. This approach will provide opportunities for AITRP trainees to develop their research career during the AITRP and then continue in a collaborative, mentored environment after the training period. This revised application includes a focused didactic curriculum for postgraduate trainees and an integrated research project experience that includes on-site training at UB and UZ. The AITRP will focus on a group of highly trained individuals who will then pursue their research programs within the multidisciplinary environment that is present at UZ with continued mentoring and career development. Strong institutional support for the proposed AITRP is evident through participation of faculty and administrative leaders at UZ in recognition of the need to support the development of future researchers to address the HIV/AIDS epidemic in Zimbabwe. PUBLIC HEALTH RELEVANCE: As the HIV/AIDS epidemic has continued to impact on developing countries, the need for training in HIV/AIDS clinical Pharmacology has also expanded in scope. Our AITRP meets these needs by providing a mechanism for multi-disciplinary training to conduct HIV/AIDS treatment research and achieve the goals that Zimbabwe has established for optimizing antiretroviral therapy and expanding its pool of clinician scientists.

描述（由申请人提供）：这是一份经修订的AITRP提案，旨在为布法罗大学（UB）和津巴布韦大学（UZ）之间的艾滋病毒/艾滋病临床药理学研究生培训计划提供重点。两所机构的项目教师都是经验丰富的研究人员，他们将为UZ的学生提供指导培训，这些学生将为多学科团队提供临床药理学专业知识，以实现津巴布韦的艾滋病毒/艾滋病研究目标。该计划旨在使AITRP学员受益于与教师和卫生专业人员在已建立的临床/转化和实验室研究环境中的指导互动。AITRP的基础设施已经扩大到包括与niaid资助的津巴布韦国际多学科研究网络的正式合作，通过UZ临床试验站点以及其他美国支持和津巴布韦的研究项目进行协调。这种方法将为AITRP受训者提供机会，在AITRP期间发展他们的研究事业，然后在培训期结束后继续在一个协作的、有指导的环境中工作。修订后的申请包括针对研究生学员的重点教学课程，以及包括UB和UZ现场培训在内的综合研究项目经验。AITRP将专注于一群训练有素的个人，他们将在UZ的多学科环境中继续从事他们的研究项目，并获得持续的指导和职业发展。由于认识到有必要支持未来研究人员的发展，以应对津巴布韦境内的艾滋病毒/艾滋病流行病，乌兹大学的教师和行政领导参加了该计划，可见机构对该计划的大力支持。公共卫生相关性：由于艾滋病毒/艾滋病流行病继续对发展中国家产生影响，对艾滋病毒/艾滋病临床药理学培训的需求也扩大了。我们的AITRP通过提供多学科培训机制来开展艾滋病毒/艾滋病治疗研究，并实现津巴布韦为优化抗逆转录病毒治疗和扩大临床科学家队伍而确定的目标，从而满足了这些需求。