Antiretroviral Pharmacology Training in Resource Poor Countries

资源匮乏国家的抗逆转录病毒药理学培训

• 批准号: 8248741
• 负责人: Gene D. Morse
• 金额: $ 30万
• 依托单位: STATE UNIVERSITY OF NEW YORK AT BUFFALO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-08 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8248741
• 关键词: AIDS/HIV problem; Address; Anti-Retroviral Agents; Buffaloes; Clinical; Clinical Pharmacology; Clinical Trials; Collaborations; Country; Developing Countries; Development; Environment; Epidemic; Faculty; Funding; Future; Goals; Health; Health Professional; Individual; Institution; Interdisciplinary Study; International; Laboratory Research; Mentors; National Institute of Allergy and Infectious Disease; Pharmacology; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Scientist; Site; Students; Training; Translational Research; Universities; Zimbabwe; antiretroviral therapy; base; career; career development; design; didactic education; experience; meetings; multidisciplinary; programs

DESCRIPTION (provided by applicant): This is a revised AITRP proposal for a postgraduate training initiative with an emphasis on HIV/AIDS clinical pharmacology between the University at Buffalo (UB) and the University of Zimbabwe (UZ). The program faculty at both institutions are experienced investigators that will contribute mentored training to UZ students who, in turn, will contribute clinical pharmacology expertise to multidisciplinary teams to achieve the HIV/AIDS research goals for Zimbabwe. The program is designed for AITRP trainees to benefit from mentored interactions with faculty and health professionals with established clinical/translational and laboratory research environments. The AITRP infrastructure has been broadened to include formalized collaboration with NIAID-funded international, multidisciplinary research networks in Zimbabwe, coordinated through the UZ Clinical Trials Site, as well as other US-supported and Zimbabwe-based research programs. This approach will provide opportunities for AITRP trainees to develop their research career during the AITRP and then continue in a collaborative, mentored environment after the training period. This revised application includes a focused didactic curriculum for postgraduate trainees and an integrated research project experience that includes on-site training at UB and UZ. The AITRP will focus on a group of highly trained individuals who will then pursue their research programs within the multidisciplinary environment that is present at UZ with continued mentoring and career development. Strong institutional support for the proposed AITRP is evident through participation of faculty and administrative leaders at UZ in recognition of the need to support the development of future researchers to address the HIV/AIDS epidemic in Zimbabwe. PUBLIC HEALTH RELEVANCE: As the HIV/AIDS epidemic has continued to impact on developing countries, the need for training in HIV/AIDS clinical Pharmacology has also expanded in scope. Our AITRP meets these needs by providing a mechanism for multi-disciplinary training to conduct HIV/AIDS treatment research and achieve the goals that Zimbabwe has established for optimizing antiretroviral therapy and expanding its pool of clinician scientists.

描述（由申请人提供）：这是一项修订的AITRP研究生培训计划的建议，重点是布法罗大学（UB）和津巴布韦大学（UZ）的HIV/AIDS临床药理学。这两个机构的计划教师都是经验丰富的调查人员，他们将为UZ学生提供指导的培训，而UZ学生又将为多学科团队贡献临床药理学专业知识，以实现津巴布韦的HIV/AIDS研究目标。该计划旨在供AITRP受训人员通过与既定的临床/转化和实验室研究环境的教师和卫生专业人员的互动受益。 AITRP基础架构已被扩展，以包括与津巴布韦的NIAID资助的国际资助的多学科研究网络的正式合作，并通过UZ临床试验网站进行了协调，以及其他美国支持的和津巴布韦的研究计划。这种方法将为AITRP受训者提供机会在AITRP期间发展研究生涯，然后在培训期间继续进行协作，指导的环境。这项修订的应用程序包括针对研究生学员的重点教学课程以及包括在UB和UZ的现场培训的集成研究项目经验。 AITRP将专注于一群受过良好训练的人，他们将在UZ的多学科环境中继续进行研究计划，并继续进行指导和职业发展。通过参与UZ的教职员工和行政领导人的参与，以认识到需要支持未来研究人员的发展，以解决津巴布韦的艾滋病毒/艾滋病流行，这是明显的。公共卫生相关性：随着艾滋病毒/艾滋病流行对发展中国家的影响，艾滋病毒/艾滋病临床药理学培训的需求也在范围内扩大。我们的AITRP通过提供多学科培训来进行艾滋病毒/艾滋病治疗研究的机制来满足这些需求，并实现津巴布韦为优化抗逆转录病毒疗法并扩大其临床医生库的目标。