Trajectories of Urologic Disease: Follow-up of BACH

泌尿系统疾病的轨迹：BACH 的随访

• 批准号: 7898193
• 负责人: John B McKinlay
• 金额: $ 25万
• 依托单位: NEW ENGLAND RESEARCH INSTITUTES, INC.
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-25 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7898193
• 关键词: Acupuncture procedure; Address; Adult; Advisory Committees; Affect; Age; American; Anthropometry; Area; Behavior; Biological Availability; Boston; Chronic Disease; Cohort Studies; Communities; Community Health; Consensus; Cross-Sectional Studies; Data; Development; Diabetes Mellitus; Disease; Disease remission; Distress; Drug usage; Elderly; Epidemiology; Ethnic Origin; Event; Female; Future; Gender; Glare; Goals; Gynecologic; Health Care Visit; Health Status; Health Surveys; Healthcare; Hispanics; Hour; Human Resources; Hypogonadism; Iceberg; Incidence; Individual; International; Interview; Interviewer; Knowledge; Life; Life Experience; Life Style; Longevity; Maintenance; Malignant neoplasm of prostate; Measures; Metabolic syndrome; Minority; Natural History; Paper; Pathway interactions; Peer Review; Pelvic Pain; Persons; Pharmaceutical Preparations; Pharmacoepidemiology; Pharmacologic Substance; Physicians; Physiological; Polypharmacy; Population; Prevalence; Primary Prevention; Procedures; Prospective Studies; Psychosocial Factor; Quality of life; Race; Recommendation; Recruitment Activity; Reproductive History; Research; Resources; Retirement; Risk; Risk Factors; Role; Sampling; Screening procedure; Self Management; Severities; Sleep; Social Functioning; Socioeconomic Status; Solid; Source; Specimen; Symptoms; Testing; Time; Unemployment; United States National Institutes of Health; Urinary Incontinence; Urologic Diseases; Variant; Venous blood sampling; Visit; Woman; abstracting; base; cohort; community health study; cost; depression; design; ethnic minority population; experience; follow-up; health care service utilization; help-seeking behavior; instrument; interest; knowledge base; male; meetings; men; novel; population based; posters; preconditioning; prospective; prostatitis; socioeconomics; treatment strategy; urologic

The Boston Area Community Health (BACH) study is filling knowledge gaps in the epidemiology of urologic problems - especially variations in prevalence and risk factors by race/ethnicity, gender, age, and socioeconomic status. A random population sample of 5,506 adults (3,205 females, 2,301 males; 1,770 Black, 1,877 Hispanic, 1,859 White) was successfully recruited (2002-2005). A 2-hour in-person interview obtained information on urologic symptoms, sociodemographics, measured anthropometries, health status and pharmaceutical usage (both prescribed and OTC), lifestyles and psychosocial factors, and health care utilization. A venous blood sample (20 mis) was obtained from a majority (70%) of subjects. Paper topics were identified and prioritized by a Scientific Advisory Committee: 43 posters and abstracts have been presented at national and international meetings; 6 peer-reviewed papers have appeared/been accepted; 13 submitted and under review; 8 are in active development; 59 topics have been identified for future papers. We propose to transition BACH from a cross-sectional to a prospective cohort design: efforts to remain in contact with subjects and a recent (2006) highly successful attempt to re-interview 500 subjects (after 4+ years) show that over 80% (n=4.130) can be re-recruited. Prospective follow-up of well-characterized subjects provides an opportunity to address questions concerning the epidemiology of urological symptoms: natural history (progression/remission) within the same subject, longitudinal relationship with major chronic diseases, pharmacoepidemiology, the role of life experiences/events, help-seeking behavior, and formal and informal costs (bother, distress and quality of life). It will provide much needed incidence rates, an opportunity to test the robustness of baseline associations, and help unravel pathophysiologic pathways. Interviews will continue to be conducted in-person (often using the same baseline interviewer) to avoid variations due to different data gathering modes. Analyses of the baseline data have informed many novel longitudinal questions. Unique features of BACH include: ¿ a random community-based sample: ¿ inclusion of race/ethnic minorities; ¿ sufficient numbers of both males and females: ¿ the broad age-span of 30-80 years: ¿ its focus on symptoms (rather than ill-defined conditions); ¿ use of validated field instruments: ¿ its multidisciplinarv orientation: ¿ its representativeness and generalizabilitv: ¿ the ready availability of biologic specimens: and the efforts to remain in current contact with all BACH subjects. This study will examine the "urologic iceberg" - the incidence of urologic symptoms in the population, risk factors, changes over time, impact on quality of life, use of health care, and the emerging burden of symptoms suggestive of urologic disease.

波士顿地区社区卫生（BACH）研究填补了知识差距 泌尿外科问题 - 尤其是种族/种族，性别，年龄和年龄和风险因素的变化 社会经济地位。 5,506名成年人的随机人群样本（3,205名女性，2,301名男性； 1,770 黑色，1,877西班牙裔，1,859 White）成功招募（2002-2005）。面对2小时的面试 获得了有关泌尿科符号，社会人口统计学，测量拟人化，健康状况的信息 以及药物使用（处方和OTC），生活方式和心理因素以及医疗保健 利用率。从大多数受试者（70％）获得静脉血液样本（20个MIS）。纸质主题 由科学咨询委员会确定并优先考虑：已有43张海报和摘要 在国家和国际会议上举行； 6个同行评审的论文已被视为/接受； 13 提交和审查； 8正在积极发展； 59个主题已被确定为未来的论文。 我们建议将巴赫从横截面过渡到前瞻性队列设计：努力留在 与受试者的接触和最近的（2006年）非常成功地尝试重新接触500名受试者（4+后 几年）表明，可以重新获得超过80％（n = 4.130）。符合特征的预期随访 受试者提供了解决有关泌尿外科症状流行病学问题的机会： 在同一主题中的自然历史（进展/缓解）与主要慢性的纵向关系 疾病，药物ePIDEMIOGON，生活经验/事件的作用，寻求帮助行为以及正式和正式 非正式成本（无论是困扰还是生活质量）。它将提供急需的事件率 测试基线关联的鲁棒性并有助于阐明病理生理途径的机会。 面试将继续面对面（通常使用相同的基线面试官）以避免 由于不同的数据收集模式而引起的变化。基线数据的分析已告知许多新颖 纵向问题。 巴赫的独特功能包括：�一个基于社区的随机样本：»种族/种族包含 少数民族； �足够数量的男性和女性：»宽30-80岁的广泛年龄跨度：它的重点 关于症状（而不是定义不明的疾病）；使用经过验证的现场仪器：»其多学科 方向：»其代表性和概括：生物标本的现成可用性： 目前与所有Bach受试者保持联系的努力。 这项研究将检查“泌尿科冰山” - 泌尿科符号在人群中的发生率，风险 因素，随着时间的变化，对生活质量的影响，医疗保健的使用以及新兴的燃烧 症状暗示泌尿科疾病。