HIV-HOST PROTEIN COMPLEXES

HIV 宿主蛋白复合物

• 批准号: 8170565
• 负责人: ALAN D FRANKEL
• 金额: $ 0.72万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8170565
• 关键词: Complex; Computer Graphics; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; HIV; Institution; Laboratories; Proteins; Proteomics; RNA; RNA-Binding Proteins; Research; Research Personnel; Resources; Source; Structure; Transcription Coactivator; United States National Institutes of Health; Work; protein complex; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have been conducting proteomic studies to identify host proteins that interact with HIV proteins in order to determine the structures of relevant complexes. Our structural studies focus primarily on complexes with the Tat transcription activator and Rev RNA export factor, both RNA-binding proteins. Graphical analyses of the structures utilizing Computer Graphics Laboratory tools are instrumental for this work.

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