Infectious Diseases and Child Health in Pakistan Research Training Program

巴基斯坦传染病和儿童健康研究培训项目

• 批准号: 7996489
• 负责人: ANITA K M ZAIDI
• 金额: $ 0.18万
• 依托单位: AGA KHAN UNIVERSITY (PAKISTAN)
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7996489
• 关键词: 5 year old; Affect; Area; Centers for Disease Control and Prevention (U.S.); Cessation of life; Child; Child Mortality; Child health care; Childhood; Collaborations; Communicable Diseases; Country; Developing Countries; Diarrhea; Economic Policy; Health; Individual; Infection; Leadership; Morbidity - disease rate; Neonatal; Newborn Infant; Pakistan; Pneumococcal Pneumonia; Pneumonia; Policy Analysis; Public Health; Research; Research Training; Rotavirus; Science; Structure; Survival Rate; Training; Training Programs; Translational Research; Universities; Vaccines; burden of illness; improved; mortality; novel vaccines; pediatric department; skills; tool; vaccine safety

DESCRIPTION (provided by applicant): Pakistan has the 4th highest burden of child mortality in the world, with an estimated 500,000 annual child deaths. Infectious diseases are the biggest killers, causing 60% of all deaths under 5 years of age. WHO estimates that neonatal infections (15%), diarrheal illnesses (17%), and pneumonia (21%) cause over 50% of all child deaths in Pakistan. Although the infectious morbidity and mortality is huge, Pakistan has no formal training programs in infectious diseases. Consequently, there is a tremendous shortage of individuals with the requisite skills to conduct independent research in infectious diseases affecting Pakistani children. The Department of Pediatrics at the Aga Khan University in Karachi, Pakistan has a strong track record in research relevant to improving child survival in developing countries. In collaboration with colleagues at Emory University and the Centers of Disease Control and Prevention in Atlanta, the Department can offer unique training opportunities in infectious diseases to Pakistani trainees. The long-term aim is to prepare a cadre of individuals who will provide the evidence, leadership, and enthusiasm needed to reduce the burden of childhood infections of major public health importance in Pakistan and other developing countries. The Infectious Diseases and Child Health in Pakistan (IDCHIP) Research Training Program will provide opportunities for structured long- and short-term training in Karachi and Atlanta with a particular focus on vaccine translational research and neonatal infections. Vaccine science is a key tool to close the health gap between children in rich and poor countries. Vaccine translational research aims to accelerate rational introduction of new vaccines (e.g. against rotavirus diarrhea and pneumococcal pneumonia) in developing countries by assessment of disease burden, vaccine safety and impact studies (trials and demonstration projects), and economic and policy analyses. Reducing neonatal infection rates is also a high priority for Pakistan with tremendous potential for improving neonatal survival rates. Thus building research skills in these two areas has particular relevance for reducing infectious disease-related child mortality in Pakistan. Non-technical Summary: Pakistan has a very high burden of infectious disease-related child deaths. This training program will equip individuals will research skills necessary to reduce the burden of infections in newborn babies and vaccine-preventable childhood illnesses in Pakistan.

说明（由申请人提供）：巴基斯坦是世界上儿童死亡率第四高的国家，估计每年有50万儿童死亡。传染病是最大的杀手，造成60%的5岁以下儿童死亡。世卫组织估计，巴基斯坦50%以上的儿童死亡是由新生儿感染（15%）、腹泻病（17%）和肺炎（21%）造成的。虽然传染病发病率和死亡率很高，但巴基斯坦没有传染病方面的正式培训方案。因此，对影响巴基斯坦儿童的传染病进行独立研究的具有必要技能的人员严重短缺。位于巴基斯坦卡拉奇的阿迦汗大学儿科系在改善发展中国家儿童生存的相关研究方面有着良好的记录。通过与埃默里大学和亚特兰大疾病控制和预防中心的同事合作，该部可以为巴基斯坦受训人员提供独特的传染病培训机会。长期目标是培养一支骨干队伍，他们将提供必要的证据、领导能力和热情，以减轻巴基斯坦和其他发展中国家具有重大公共卫生重要性的儿童感染负担。巴基斯坦传染病和儿童健康研究培训方案将在卡拉奇和亚特兰大提供有组织的长期和短期培训机会，特别侧重于疫苗转化研究和新生儿感染。疫苗科学是缩小富国和穷国儿童健康差距的关键工具。疫苗转化研究旨在通过评估疾病负担、疫苗安全性和影响研究（试验和示范项目）以及经济和政策分析，加速在发展中国家合理引进新疫苗（例如针对轮状病毒腹泻和肺炎球菌肺炎的疫苗）。降低新生儿感染率也是巴基斯坦的一项高度优先事项，在提高新生儿存活率方面具有巨大潜力。因此，在这两个领域建立研究技能对降低巴基斯坦与传染病有关的儿童死亡率具有特别重要的意义。非技术摘要：巴基斯坦与传染病有关的儿童死亡负担非常高。这一培训计划将使个人具备必要的研究技能，以减轻巴基斯坦新生儿感染和疫苗可预防的儿童疾病的负担。