South Africa Tuberculosis/AIDS Training

描述(申请人提供)：南非是世界上结核病负担最高、结核病/艾滋病毒负担最高和艾滋病毒负担最高的五个国家之一。缺乏在临床、业务和卫生服务研究方面经验丰富的调查人员S是南非未能实现其结核病控制目标的主要原因之一。这是来自三所南非大学(威特沃特斯兰德大学、开普敦大学、斯泰伦博什大学)和两所美国大学(约翰·霍普金斯大学和北卡罗来纳大学教堂山分校)的两项先前规划拨款的综合申请，以创建一个全面的结核病培训计划。我们将在南非教授艾滋病毒、结核病、研究方法和研究伦理方面的短期课程，寻找有才华的南非人在南非和美国接受中长期培训，在培训期间对他们进行指导，在培训完成后资助他们进行初步研究，并帮助他们在南非建立独立的职业生涯。我们还与马拉维大学ICOHRTA建立了联系，以提供从南到南的培训机会和其他三笔Fogarty赠款：比勒陀利亚大学的Douglas Wassnaar--生物伦理学培训；比勒陀利亚大学和耶鲁大学的Mike Merson和Mary Crewe--艾滋病毒预防培训；夸祖鲁-纳塔尔大学和哥伦比亚大学的Slim Karim。具体目标：1通过21个学生年的公共卫生硕士/博士学位和28个中期经验培训一支高级教员队伍，开展手术、保健服务和临床研究，研究与南非有关的结核病/艾滋病毒问题。2.通过在赠款管理、良好临床实践、人类受试者保护、基础流行病学和结核病与艾滋病毒S方面的短期经验，培训一支由初级教职员工、政府和非政府组织工作人员组成的干部队伍。培训一支至少由来自政府、学术界和非政府组织的4名领导人组成的团队，通过在北卡罗来纳大学公共卫生领导项目中的领导力培训，以协调一致的方式工作。在南非创建一个不需要美国研究人员投入的可持续结核病培训计划5.加强威特沃特斯兰德大学、开普敦大学、比勒陀利亚大学在整个南非的艾滋病毒/结核病调查人员之间的联系StellenBosch大学和夸祖鲁-纳塔尔大学通过年度会议重点讨论结核病/艾滋病毒问题。

DESCRIPTION (provided by applicant): South Africa is one of the five countries worldwide that rank in the top ten of highest TB burden, highest TB/HIV burden and highest HIV burden. The lack of experienced investigators in clinical, operational and health services research s one of the main reasons behind the failure of South Africa to meet its tuberculosis control targets. This is a combined application from two prior planning grants from three South African universities (University of the Witwatersrand, University of Cape Town, Stellenbosch University) and two US universities (Johns Hopkins and University of North Carolina at Chapel Hill) to create a comprehensive TB training program. We shall teach short term courses in HIV, TB, research methods and research ethics in South Africa, identify talented South Africans for intermediate and long term training in South Africa and the US, mentor them throughout their training, fund them for preliminary research after completion of training and help them establish independent careers in South African. We have also established a link with the University of Malawi ICOHRTA to provide South to South training opportunities and the three other Fogarty grants: Douglas Wassnaar-bioethics training at University of Pretoria; Mike Merson and Mary Crewe-HIV prevention training at University of Pretoria and Yale; Slim Karim at University of KwaZulu-Natal and Columbia. Specific aims: 1 Train a cadre of senior faculty through 21 student years of MPH/PhD and 28 intermediate term experiences to carry out operations, health services and clinical research studying TB/HIV questions relevant to South Africa. 2.Train a cadre of junior faculty and staff, government and NGO staff through short term experiences in grants management, Good Clinical Practice, Human subjects protections, basic epidemiology and TB and HIV S.Train a team of at least 4 leaders from government, academia and NGOs to work in a cohesive manner through leadership training in the Public Health Leadership program at UNC 4.Create a sustainable TB training program in South Africa which does not require US investigator input 5.Strengthen the linkages of HIV/TB investigators throughout South Africa at University of the Witwatersrand, University of Cape Town, University of Pretoria, Stellenbosch University and University of KwaZulu-Natal through annual meetings focused on TB/HIV.