Microarray Center for Research on the Nervous System
Microarray Center for Research on the Nervous System
批准号:
7665517
负责人:
David W Craig
金额:
$119.47万
依托单位国家:
美国
项目类别:
财政年份:
2005
资助国家:
美国
项目状态:
已结题
起止时间:
2005-08-01 至 2011-05-31
关键词:
AuthorshipBackBioinformaticsBusinessesChargeDataData AnalysesData FilesDatabasesDevelopmentEducationEnsureEnvironmentEquilibriumExperimental DesignsExtramural ActivitiesFundingGenerationsGenomicsGenotypeGoalsGrantHousingInstitutionIntellectual PropertyInternetLogisticsMethodsMolecular ProfilingMonitorNational Institute of Mental HealthNational Institute of Neurological Disorders and StrokeNervous system structureNeurosciencesOnline SystemsOperative Surgical ProceduresPoliciesPriceProcessProperty RightsProtocols documentationPublic PolicyPublicationsQualifyingQuality ControlResearchResearch InfrastructureResearch InstituteResearch PersonnelReview CommitteeRoleSamplingScheduleScientistServicesSiteStructureSupercomputingTechniquesTechnologyTimeTrainingTranslationsUnited States National Institutes of HealthUniversitiesWorkbasecostdata sharingexperienceprogramsresearch and developmentresearch studysuccesstechnology developmenttoolweb site
中文摘要
描述(由申请人提供):
英文摘要
DESCRIPTION (provided by applicant):
The Translational Genomics Research Institute (TGen), a current NINDS NIMH Microarray Consortium center, offers this renewal application. The highest quality assistance with experimental design, data generation, data interpretation, and data dissemination will be provided. TGen already fulfills these functions for NINDS and NIMH extramural investigators/consortia, and has well-established protocols, web site and data repository, and bioinformatic methods which permit a high degree of throughput at low cost. The TGen center team are uniquely qualified because we have amassed significant expertise through 1) having performed this identical function as a consortium site for the past two years, 2) becoming a "Center of Excellence" for Affymetrix technology, 3) development of the consortium web portal (arrayconsortium.tgen.org) for tutorials, transparent work-flow management and progress monitoring, role dependent information access, and data dissemination, 4) ensuring MIAME compliant data and building the first MAGE-ML translation engine for HIPAA-compliant data sharing, 5) being well-versed in expression technology (Dr. Jeffrey Trent was involved in developing array technologies and the PI working with Affymetrix technology for the past seven years), 6) having performed over 2635 Affymetrix array experiments for the consortium in its first two years and receiving excellent reviews, 7) operation of the TGen center with a business infrastructure, and 8) having Dr. Stephan Chair the consortium for its entire 3 year existence. We propose to continue operating our NINDS NIMH Microarray Center. The proposed structure/function is anchored in experience, except for the R&D portions of the proposal. The goals include: 1) tutorials and project submission via the web, 2) review by an internal review committee with neuroscience experience, 3) standardized pricing for services across the consortium, 4) data generation on Affymetrix stock chips and analysis, 5) data warehousing with 6 month timed release to the public, and 6) technology development.
期刊论文(7)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1016/j.neulet.2011.07.048
发表时间:
2011-09-20
期刊:
Neuroscience letters
影响因子:
2.5
作者:
[Hjelm BE, Rosenberg JB, Szelinger S, Sue LI, Beach TG, Huentelman MJ, Craig DW]
通讯作者:
Craig DW
Genome Characterization Unit
-
批准号:10294887
-
项目类别:
-
资助金额:$171.95万
-
财政年份:2021
-
负责人:David W Craig
-
依托单位:
Genome Characterization Unit
-
批准号:10696242
-
项目类别:
-
资助金额:$54.22万
-
财政年份:2021
-
负责人:David W Craig
-
依托单位:
Genome Characterization Unit
-
批准号:10492738
-
项目类别:
-
资助金额:$160.95万
-
财政年份:2021
-
负责人:David W Craig
-
依托单位:
The Bipolar Genome Study
-
批准号:8495419
-
项目类别:
-
资助金额:$66.74万
-
财政年份:2012
-
负责人:David W Craig
-
依托单位:
The Bipolar Genome Study
-
批准号:8660561
-
项目类别:
-
资助金额:$67.65万
-
财政年份:2012
-
负责人:David W Craig
-
依托单位:
The Bipolar Genome Study
-
批准号:8304601
-
项目类别:
-
资助金额:$82.75万
-
财政年份:2012
-
负责人:David W Craig
-
依托单位:
Data Processing and Visualization for 1000 Genomes
-
批准号:7760707
-
项目类别:
-
资助金额:$71.8万
-
财政年份:2009
-
负责人:David W Craig
-
依托单位:
Data Processing and Visualization for 1000 Genomes
-
批准号:7929662
-
项目类别:
-
资助金额:$71.08万
-
财政年份:2009
-
负责人:David W Craig
-
依托单位:
Design and Analysis of Multi-Staged Association Studies Using Pooled Genomic DNA
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批准号:7452403
-
项目类别:
-
资助金额:$35.93万
-
财政年份:2006
-
负责人:David W Craig
-
依托单位:
Molecular Genomics Core
-
批准号:10620227
-
项目类别:
-
资助金额:$62.45万
-
财政年份:1996
-
负责人:David W Craig
-
依托单位:
国内基金
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负责人:郭兴龙
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