Principal Research Core

主要研究核心

• 批准号: 8072124
• 负责人: GEORGE S ALEXOPOULOS
• 金额: $ 63.8万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8072124
• 关键词: Address; Biological; Biology; Biometry; Budgets; Caring; Clinical; Clinical Research; Collaborations; Communities; Community Networks; Community Practice; County; Data; Depressed mood; Development; Economics; Elderly; Faculty; Foundations; Funding; Healthcare; Home environment; Hospitals; Intervention; Intervention Studies; K-Series Research Career Programs; Lead; Leadership; Mental Health; Methodological Studies; Mission; National Institute of Mental Health; Outcome; Patient Care; Pilot Projects; Primary Health Care; Process; Recording of previous events; Rehabilitation therapy; Research; Research Methodology; Research Personnel; Risk; Social Work; Stimulus; System; Testing; Time; Translating; United States National Institutes of Health; Wages; Work; career development; community based service; community setting; design; experience; geriatric depression; geriatric mental health; innovation; neglect; operation; programs; psychosocial; research and development; social; treatment response

The Principal Research Core's (PRC) mission is to serve as the conceptual architect of the ACISR's research program. To this end, the PRC will promote studies on clinical, psychosocial, and biological predictors of outcomes and moderators of treatment response of geriatric depression and use their findings as a stimulus for developing interventions personalizing care at the patient and the care setting level. A central function of the PRC will be to promote designs that permit testing of interventions at community settings at the soonest possible time that evidence of efficacy permits. The PRC relies on: 1. Investigators with long experience in research planning and complementary expertise in clinical biology, social systems, primary care, home healthcare and rehabilitation studies, biostatistics, and economics with long history of collaboration and ability to integrate their perspectives into cohesive hypotheses; 2. an organization that rapidly translates biological and psychosocial findings and clinical experience into intervention studies; 3. a track record of independently supported projects (10 funded by NIH and 8 by Foundations in the past year); 4. experience in career development of investigators (currently 8 NIMH K Awards are supported by the ACISR); and 5. working research partnerships with the Westchester Geriatric Mental Health Coalition, which includes the County Department of Mental Health, the County Department of Senior Programs and Services, community based primary care practices, rehabilitation hospitals; home healthcare agencies; and other social services. The process of research development and coordination depends on the PRC Management Team developing initiatives that integrate our expertise and research findings with community input on the needs of depressed older adults and the strengths and limitations of the settings that care for them. Developmental Projects 1, 2 and 3, Pilot 1 and 2, and the CNU Research Initiatives presented in this application exemplify this process. The PRC works closely with the Research Methods Core (RMC); it provides to the RMC a stimulus and data for its methodological studies, while it incorporates the RMC innovations in the designs of substantive studies. Jointly with the Community Network Unit of the Operations Core and the ACISR community partners, the PRC conceptualizes and supports studies with the potential to bring care to large numbers elders of our community, inclusing those neglected by traditional clinical research.

主要研究核心（PRC）的使命是作为ACISR的概念建筑师 研究计划。为此，中国将促进有关临床，社会心理和生物学的研究 预测老年抑郁症治疗反应的预测因素和主持人并使用其发现 作为制定干预措施在患者和护理设置水平的刺激。一个 中国的中心功能将是促进允许在社区进行干预措施测试的设计 设置有效性允许的最大可能时间。 中国依赖于：1。在研究计划和互补专业知识方面经验丰富的研究人员 在临床生物学，社会系统，初级保健，家庭医疗保健和康复研究，生物统计学以及 经济学具有悠久的协作历史和能够将其观点融入凝聚力的能力 假设； 2。一个迅速翻译生物学和社会心理发现和临床的组织 经验干预研究； 3。独立支持的项目的记录（10由NIH资助 在过去的一年中由基金会8）； 4。研究人员的职业发展经验（目前8个 NIMH K奖项得到了ACISR的支持； 5。与威彻斯特的研究合作伙伴关系 老年心理健康联盟，其中包括县心理健康部 高级计划和服务部，基于社区的初级保健实践，康复 医院；家庭医疗机构；和其他社会服务。 研究开发和协调的过程取决于中国管理团队 将我们的专业知识和研究结果与社区投入的计划相结合的计划 老年人以及关心他们的设置的优势和局限性。发展项目1，2 3，试点1和2，以及本申请中提出的CNU研究计划，体现了这一过程。 中国与研究方法核心（RMC）紧密合作；它为RMC提供了刺激和数据 对于其方法论研究，虽然将RMC创新纳入实质性的设计中 研究。与运营核心和ACISR社区的社区网络部门共同 合作伙伴，中国概念化并支持研究，有可能将大量护理带来 我们社区的长老，包括那些被传统临床研究所忽视的人。