Administrative Core

管理核心(AC)摘要 在此基础上，我们提出了一种以部署为中心的个性化干预模型方案 在研究很少针对的环境中，有未得到满足的需求的抑郁的中老年人。我们的T2 干预措施由消费者提供信息，与社区合作伙伴共同开发并实施 由社区服务人员提供服务，以加速现实世界的变革。他们来自RDoC，他们是 简化了基于神经生物学和评估行为目标的参与度。我们使用移动医疗 增强行为评估和指导治疗师针对他们的干预措施的技术。 空调中心将成为中心的枢纽和：1.利用我们20多年来管理NIMH中心的经验 将消费者和社区合作伙伴的关切融入创新的T2研究；2.提供 科学和后勤支持的结构，以及对工作人员的培训；3.依靠我们的“专有技术”、记录和明确 与社区机构发展持久伙伴关系并从中学习的计划；4.利用 我们的方法严谨；以及5.利用我们在研究事业发展方面的经验。我们的目标是： 1.建立一个沟通和决策结构，促进消费者和 社区合作伙伴关注的问题、科学目标、项目和方法倡议 跨学科，T2研究。执行委员会(EC)，由消费者、社区合作伙伴 和专业顾问，将在几个工作组的参与下组织中心的职能。 2.指导有情绪障碍的中老年人士找出未获满足的需要，以及 接触为他们提供服务的社区机构。一个社区融合委员会将协助我们实现这一目标。 3.为项目提供业务支持，以确保高质量的研究和促进 招聘和协作。干预管理小组将提供干预咨询 设计和忠诚度、评估、仪器和数据共享、招聘和研究协调。 4.在康奈尔大学促进中老年情绪障碍的研究、培训和职业发展，并提供 在全国职业发展中处于领先地位。这一努力将由一个领导人委员会带头 指导资助的培训计划。 5.与方法核心协作，制定衡量标准并监测中心的进展。《中心》 将使用医疗保健改进研究所的持续质量改进方法并明确设置 其项目的里程碑和研究方法核心倡议。 6.仿照国立卫生研究院的赠款征集、审查和监测程序，组织一项试点项目方案 这充分利用了该中心的资源，延长了其研究议程。

ADMINISTRATIVE CORE (AC) ABSTRACT We propose a novel deployment focused model program of personalized interventions stimulated by our work with depressed older and middle-aged adults with unmet needs in settings rarely targeted by research. Our T2 interventions are informed by consumer input, developed together with community partners, and implemented by staff of community services so that they accelerate change in the real world. Drawing from RDoC, they are simplified based on neurobiology and assess engagement of behavioral targets. We use mobile health technology to augment behavioral assessment and to guide therapists in targeting their interventions. The AC will be the Center's hub and: 1. Utilize our experience in adminstering an NIMH Center over 20 years to integrate the concerns of consumers and community partners into innovative T2 studies; 2. Provide structures for scientific and logistic support, and training of staff; 3. Rely on our “know-how”, record, and explicit plans for developing sustained partnerships with community agencies and learning from them; 4. Capitalize on our methodological rigor; and 5. Bring to bear our experience in research career development. Our aims are to: 1. To develop a communication and decision-making structure that promotes synergy among consumers' and community partners' concerns, scientific aims, projects, and methods initiatives in pursuing innovative, transdisciplinary, T2 research. An executive committee (EC), consisting of consumers, community partners and specialized advisors, will organize the Center's functions with input by several Work Groups. 2. To provide guidance in identifying unmet needs of older and middle aged adults with mood disorders and access to community agencies serving them. A Community Integration Committee will assist us in this aim. 3. To offer operational support to projects in order to ensure high quality of research and to promote recruitment and collaboration. An Intervention Management Team will provide consultation on intervention design and fidelity, assessment, instrument and data sharing, recruitment, and research coordination. 4. To foster research training and career development in late- and mid-life mood disorders at Cornell and offer leadership in career development nationally. This effort will be spearheaded by a committee of leaders directing funded training programs. 5. To develop metrics and monitor the Center's progress in collaboration with the Methods Core. The Center will use the Institute for Healthcare Improvement Continuous Quality Improvement approach and set explicit milestones for its projects, and the Research Methods Core initiatives. 6. Organize a pilot project program, modeled after the NIH grant solicitation, review and monitoring process that capitalizes on the Center's resources and extends its research agenda.