Administrative Core

行政核心

• 批准号: 10016860
• 负责人: GEORGE S ALEXOPOULOS
• 金额: $ 72.89万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-22 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10016860
• 关键词: Address; Adult; Assessment tool; Behavior assessment; Behavioral; Collaborations; Communication; Communities; Community Integration; Community Services; Consultations; Decision Making; Depressed mood; Elderly; Ensure; Fostering; Funding; Goals; Grant; Health Technology; Healthcare; Institutes; Intervention; Leadership; Learning; Logistics; Methodology; Methods; Modeling; Monitor; Mood Disorders; National Institute of Mental Health; Neurobiology; Outcome; Pilot Projects; Process; Research; Research Domain Criteria; Research Methodology; Research Training; Resources; Structure; Targeted Research; Training; Training Programs; United States National Institutes of Health; Ursidae Family; Work; base; career development; community setting; data sharing; experience; innovation; mHealth; middle age; novel; personalized intervention; programs; recruit; synergism; therapy design; working group

ADMINISTRATIVE CORE (AC) ABSTRACT We propose a novel deployment focused model program of personalized interventions stimulated by our work with depressed older and middle-aged adults with unmet needs in settings rarely targeted by research. Our T2 interventions are informed by consumer input, developed together with community partners, and implemented by staff of community services so that they accelerate change in the real world. Drawing from RDoC, they are simplified based on neurobiology and assess engagement of behavioral targets. We use mobile health technology to augment behavioral assessment and to guide therapists in targeting their interventions. The AC will be the Center's hub and: 1. Utilize our experience in adminstering an NIMH Center over 20 years to integrate the concerns of consumers and community partners into innovative T2 studies; 2. Provide structures for scientific and logistic support, and training of staff; 3. Rely on our “know-how”, record, and explicit plans for developing sustained partnerships with community agencies and learning from them; 4. Capitalize on our methodological rigor; and 5. Bring to bear our experience in research career development. Our aims are to: 1. To develop a communication and decision-making structure that promotes synergy among consumers' and community partners' concerns, scientific aims, projects, and methods initiatives in pursuing innovative, transdisciplinary, T2 research. An executive committee (EC), consisting of consumers, community partners and specialized advisors, will organize the Center's functions with input by several Work Groups. 2. To provide guidance in identifying unmet needs of older and middle aged adults with mood disorders and access to community agencies serving them. A Community Integration Committee will assist us in this aim. 3. To offer operational support to projects in order to ensure high quality of research and to promote recruitment and collaboration. An Intervention Management Team will provide consultation on intervention design and fidelity, assessment, instrument and data sharing, recruitment, and research coordination. 4. To foster research training and career development in late- and mid-life mood disorders at Cornell and offer leadership in career development nationally. This effort will be spearheaded by a committee of leaders directing funded training programs. 5. To develop metrics and monitor the Center's progress in collaboration with the Methods Core. The Center will use the Institute for Healthcare Improvement Continuous Quality Improvement approach and set explicit milestones for its projects, and the Research Methods Core initiatives. 6. Organize a pilot project program, modeled after the NIH grant solicitation, review and monitoring process that capitalizes on the Center's resources and extends its research agenda.

行政核心（AC）摘要 我们提出了一个新的部署集中模型程序的个性化干预刺激我们的工作 在研究很少针对的环境中，老年人和中年人患有抑郁症，需求未得到满足。我们的T2 根据消费者的意见制定干预措施，与社区合作伙伴共同制定并实施 社区服务的工作人员，这样他们就可以加速真实的世界的变化。根据RDoC，它们是 基于神经生物学进行简化，并评估行为目标的参与。我们使用移动的健康 技术，以增强行为评估和指导治疗师在针对他们的干预措施。 AC将是中心的枢纽和：1.利用我们在管理NIMH中心超过20年的经验 将消费者和社区合作伙伴的关注纳入创新的T2研究; 2.提供 科学和后勤支助的结构以及工作人员的培训; 3.依靠我们的“专业知识”、记录和明确的 与社区机构建立持续伙伴关系并向其学习的计划; 4.利用 我们的方法论严谨; 5.发挥我们在研究职业发展方面的经验。我们的目标是： 1.建立一个沟通和决策结构，促进消费者和 社区合作伙伴的关注，科学目标，项目和方法倡议，在追求创新， 跨学科的T2研究执行委员会（EC），由消费者、社区合作伙伴 和专业顾问，将组织中心的职能与投入的几个工作组。 2.为确定患有情绪障碍的老年人和中年人未满足的需求提供指导， 社区机构为他们服务。一个社区融合委员会将协助我们实现这一目标。 3.为项目提供业务支持，以确保高质量的研究，并促进 招聘与合作。干预管理小组将提供干预咨询 设计和保真度，评估，仪器和数据共享，招募和研究协调。 4.在康奈尔大学促进晚年和中年情绪障碍的研究培训和职业发展，并提供 在全国范围内的职业发展。这一努力将由一个由领导人组成的委员会牵头 指导资助的培训项目。 5.与方法核心合作制定指标并监测中心的进展。中心 将使用医疗保健改进研究所持续质量改进方法，并明确 其项目的里程碑，以及研究方法的核心举措。 6.组织一个试点项目计划，仿照NIH的资助申请、审查和监测过程 利用该中心的资源并扩展其研究议程。