Support for the recruit of a tenure track faculty member, Lie Gao, M.D., Ph.D.

支持聘任终身教职人员高烈（Lie Gau）医学博士、博士。

• 批准号: 7995955
• 负责人: Irving H Zucker
• 金额: $ 58.24万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7995955
• 关键词: Academic Medical Centers; Angiotensin II Receptor; Angiotensin Receptor; Animals; Appointment; Area; Blood Circulation; Brain Stem; Cardiovascular Physiology; Cardiovascular system; Cell physiology; Chairperson; Chronic; Data; Diabetes Mellitus; Disease; Doctor of Medicine; Doctor of Philosophy; Equipment; Faculty; Funding; Heart failure; Hypertension; Hypothalamic structure; Indium; Institution; Kidney; Laboratories; Medical center; Mus; Nebraska; Physiology; Process; Program Research Project Grants; Rattus; Recruitment Activity; Regulation; Request for Proposals; Research; Research Personnel; Research Support; Resources; Transfection; Type 2 Angiotensin II Receptor; Universities; Wages; Work; member; neuroregulation; professor; ranpirnase; research study; response; success

DESCRIPTION (provided by applicant): This P30 application Is in response to RFA-OD-09-005. We request approximately $500,000/year for salary support and startup funds to elevate Dr. Lie Gao to a tenure track Assistant Professor in the Department of Cellular and Integrative Physiology (CIP) at the University of Nebraska IVIedical Center (UNMC). CIP has had a focus of cardiovascular and renal physiology for the past 40 years. Upon Dr. Irving Zucker becoming Chairman in 1989 cardiovascular physiology became even more prominent following strategic recruitments and the acquisition of a Program Project Grant to study the neural control of the circulation in chronic heart failure. The recruitment of Dr. Gao from a Research Assistant Professor, which is a special appointment at this institution to an Assistant Professor on the Tenure Track will contribute to the strategic recruitments in cardiovascular and renal physiology. Dr. Gao will bring specific expertise to our group in his ability to evaluate sympathetic function in rats and mice and his expertise at central recording in animals with heart failure. His adenoviral transfection experiments will provide important new data on the contribution of Angiotensin II receptors to the sympatho-excitatory process in heart failure. His experiments will revolve around the area of the regulation of angiotensin receptors in the autonomic regulatory areas in the brain stem and hypothalamus. He will especially focus on the Angiotensin Type 2 receptor in these studies. Currently, his work is being carried out in space and with equipment that belongs to Dr. Zucker. In order to achieve independence he will need his own space and equipment. UNMC will provide support for Dr. Gao's salary for 2 years following the completion of this P30. The Department of CIP will provide Dr. Gao with his own laboratory and office space. All the resources exist at UNMC and in CIP to maximize the likelihood of success in his research. Support for the recruitment of a tenure track faculty member, Lie Gao, M.D., Ph.D. for salary support and startup funds to elevate Dr. Lie Gao to a tenure track Assistant Professor in the Department of Cellular and Integrative Physiology (CIP) at the University of Nebraska Medical Center (UNMC).

描述(申请人提供)：本P30申请是对RFA-OD-09-005的回应。我们要求每年大约500,000美元的工资支持和启动资金，以将Lie Gao博士提升为内布拉斯加大学IVIedical Center(UNMC)细胞和综合生理学(CIP)系的终身教职助理教授。在过去的40年里，CIP一直是心血管和肾脏生理学的研究重点。1989年欧文·扎克博士出任董事长后，心血管生理学在战略招聘和获得研究慢性心力衰竭循环神经控制的项目拨款后变得更加突出。从研究助理教授招聘高博士，这是该机构的一项特殊任命，将有助于心血管和肾脏生理学的战略招聘。高博士将为我们小组带来评估大鼠和小鼠交感神经功能的能力方面的具体专业知识，以及对心力衰竭动物进行中央记录的专业知识。他的腺病毒转染实验将为血管紧张素II受体在心力衰竭的交感兴奋过程中的作用提供重要的新数据。他的实验将围绕脑干和下丘脑自主神经调节区中血管紧张素受体的调节区域展开。在这些研究中，他将特别关注血管紧张素2型受体。目前，他的工作正在太空中进行，使用的是扎克博士的设备。为了实现独立，他需要自己的空间和设备。在本P30完成后，UNMC将为高博士提供两年的工资支持。CIP部门将为高博士提供自己的实验室和办公场所。所有资源都存在于UNMC和CIP中，以最大限度地提高他研究成功的可能性。 支持招聘终身教职员工Lie Gao，医学博士和博士，以获得工资支持和启动资金，将Liao博士提升为内布拉斯加大学医学中心(UNMC)细胞和综合生理学(CIP)系的终身教职跟踪助理教授。