Faculty Recruitment and Core Resource Development in Stem Cell Biology

描述（由申请人提供）：本P30申请的总体目标是通过干细胞资源的开发，提高对心血管、肺部和血液疾病的理解和治疗的研究能力。为了实现这一目标，我们建议聘请in - hyun Park博士作为新成立的发育生物学系的终身教职教师，直接响应RFA-OD-09-005“恢复法案有限竞争：支持新教师招聘，通过生物医学研究核心中心增加研究资源”（P30）。Park博士在干细胞研究方面拥有丰富的经验，并从患有多种疾病的患者身上产生了首批诱导多能干细胞（iPS）。朴博士的成功招聘，以及其他高水平的终身教职人员，将随着新干细胞核心的开发而得到加强。因此，P30提案的三个具体目标包括：招募干细胞生物学领域的终身教职人员；2 .创建干细胞中心，通过全校共享的干细胞生产和分配资源来支持和加强干细胞研究；通过干细胞核心建立人才培训和开发新干细胞技术的管道，以加强干细胞研究。朴博士将担任干细胞中心主任，为中心提供科学监督。他将得到一名助理主任的协助，该助理主任将管理中心的日常活动。由大学不同学系/分部的教员组成的咨询委员会将协助制定核心的运作政策。这将包括有关人类干细胞研究的伦理问题的指导。此外，将成立一个重叠的指导委员会，协助朴博士制定教师发展计划，并在平衡和优先考虑朴博士的研究需求与核心的其他需求方面提供指导。这种管理和领导结构将提高新教师招聘的研究效率，同时促进其他对干细胞研究感兴趣的教师的工作。

DESCRIPTION (provided by applicant): The overarching goal of this P30 application is to enhance research capacity in the understanding and treatment of cardiovascular, pulmonary, and blood diseases through the development of stem cell resources. To accomplish this, we propose to recruit and hire Dr. In-Hyun Park as tenure tract faculty in the newly formed Department of Developmental Biology, in direct response to RFA-OD-09-005 "Recovery Act Limited Competition: Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research Core Centers" (P30). Dr. Park possesses a wealth of experience in stem cell research and has generated some of the first induced pluripotent stem (iPS) cells from patients with a wide range of diseases. The successful recruitment of Dr. Park, and later, other highly qualified tenure tract faculty will be augmented by the development of a new Stem Cell Core. Hence, the three specific aims of this P30 proposal comprises: 1. Recruit new tenure track faculty in the field of stem cell biology, 2. Create a Stem Cell Core to support and enhance stem cell research via a university-wide shared resource for the production and distribution of stem cells, and 3. Create through the Stem Cell Core, a pipeline for personnel training and development of new stem cell technologies to enhance stem cell research. Dr. Park will serve as the Director of the Stem Cell Core, providing scientific oversight for the Core. He will be assisted by an assistant director who will manage the day to day activities of the Core. An advisory committee comprised of faculty from different departments/divisions of the University will be assembled to assist with establishing policies for running the core. This will include guidance on ethics issues related to human stem cell research. In addition, an overlapping mentoring committee will be assembled to assist Dr. Park with a faculty development plan and to provide guidance on balancing and prioritizing Dr. Park's research needs with other demands of the Core. This administrative and leadership structure will enhance the research productivity of the new faculty recruit, and at the same time, facilitate the work of other faculty interested in stem cell research. Overall, the recruitment of Dr. Park, the establishment of this Stem Cell Core, and the creation of the Dept of Developmental Biology reflect the University's multidisciplinary approach to biomedical research, and fills a gap that exists with respect to stem cell resources. Placement of the Stem Cell Core in the new Department at the Ranges Research Center will encourage the integration of basic science investigation into developmental mechanisms with clinical investigation into disease mechanisms. Together, the successful implementation of these endeavors, will promote interdisciplinary stem cell based translational research and the development of new, innovative therapies.