Mount Desert Island Stem Cell Symposium

山漠岛干细胞研讨会

• 批准号: 8005471
• 负责人: LEONARD Ira ZON
• 金额: $ 1.1万
• 依托单位: MOUNT DESERT ISLAND BIOLOGICAL LAB
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8005471
• 关键词: 8 year old; Address; Animal Model; Area; Biological; Clinical; Clinical Investigator; Communities; Development; Disease; Epigenetic Process; Faculty; Fishes; General Population; Generations; Genetic Transcription; Human; Invertebrates; Island; Laboratories; Maine; Medical center; Mus; National Institute of General Medical Sciences; Natural regeneration; Nature; Regulation; Research; Research Institute; Research Personnel; Role; Scientific Advances and Accomplishments; Stem Cell Research; Stem cells; Therapeutic; Tissues; Work; Yeasts; Zebrafish; base; comparative; fly; human stem cells; interest; lectures; meetings; mouse model; novel therapeutic intervention; nuclear reprogramming; programs; public health relevance; research study; stem; stem cell biology; stem cell differentiation; stem cell therapy; symposium; tissue regeneration

DESCRIPTION (provided by applicant): The Mount Desert Island Biological Laboratory (MDIBL), The Jackson Laboratory (JAX), and the Maine Medical Center Research Institute (MMCRI) propose to continue the eight-year-old Mount Desert Island Stem Cell Symposium with three annual meetings from 2010 to 2012 with support from the National Institute of General Medical Sciences. The proposed symposia, to be held annually in August 2011, 2012, and 2013 at the Mount Desert Island Biological Laboratory in Salisbury Cove, Maine, will be the 9th, 10th, and 11th Mount Desert Island Stem Cell Symposia since the meeting was established in August 2002. The 2010 Symposium on 'Reprogramming and Epigenetics', will be held August 6 - 7, 2010. The Mount Desert Island Stem Cell Symposium will emphasize epigenetics and nuclear reprogramming in the generation and differentiation of stem cells, and the role of stem and progenitor cells in tissue regeneration. The conference will continue to engage the research strengths of MDIBL, JAX, and MMCRI by emphasizing comparative stem cell research in human, mouse, fish, and invertebrates, a programmatic approach unique to this meeting. The Organizing Committee, comprised of national leaders in biomedical and stem cell research, has developed the program of this symposium to address topical issues important to the stem cell research community. The specific aims of the 2010 symposium are: 1.) Present and discuss research studies of epigenetic regulation of gene transcription and expression in stem cells; 2.) Present and discuss scientific advances in nuclear reprogramming; 3.) Present and discuss research studies of stem cells in tissue development and regeneration; 4.) Present and discuss research in which comparative models (mouse, zebrafish, worm, fly, yeast) are utilized to study epigenetic regulation; and 5.) Provide substantial opportunities for interaction between trainees, investigators new to stem cell research, and investigators well established in these research areas. Scientific sessions will include platform presentations, a trainee/faculty networking lunch, and a lecture open to the general public. PUBLIC HEALTH RELEVANCE: The Mount Desert Island Stem Cell Symposium convenes leading investigators whose work in stem cell biology is focused on a variety of model organisms including human. The comparative nature of the meeting represents the critical need for a broad-based understanding of stem cell biology required to advance the use of human stem cells in new therapeutic approaches to disease. The invited speakers (and the organizing committee) include many clinical investigators interested in therapeutic applications of stem cell research. Their clinical interests keep stem cell therapies at the forefront of the discussion.

描述（由申请人提供）：荒岛山生物实验室（MDIBL），杰克逊实验室（JAX）和缅因州医学中心研究所（MMCRI）提议在美国国家普通医学科学研究所的支持下，在2010年至2012年期间继续举办为期八年的荒岛山干细胞研讨会，每年举行三次会议。本次研讨会将于2011年8月、2012年8月和2013年8月在缅因州索尔兹伯里湾的Mount Desert Island生物实验室举行，这将是自2002年8月会议成立以来的第9、10和11届Mount Desert Island干细胞研讨会。2010年“重编程与表观遗传学”研讨会将于2010年8月6日至7日举行。荒岛干细胞研讨会将着重于干细胞的产生和分化中的表观遗传学和核重编程，以及干细胞和祖细胞在组织再生中的作用。会议将继续利用MDIBL、JAX和MMCRI的研究优势，强调在人类、小鼠、鱼类和无脊椎动物中进行比较干细胞研究，这是本次会议独特的程序化方法。由生物医学和干细胞研究领域的国家领导人组成的组委会制定了本次研讨会的计划，以解决对干细胞研究界重要的专题问题。2010年研讨会的具体目标是：1)介绍和讨论干细胞中基因转录和表达的表观遗传调控的研究进展；2.） 介绍和讨论核重编程的科学进展；3)。介绍和讨论干细胞在组织发育和再生中的研究；4)。介绍和讨论利用比较模型（小鼠、斑马鱼、蠕虫、苍蝇、酵母）研究表观遗传调控的研究；和5)。为受训者、干细胞研究的新研究者和在这些研究领域建立良好的研究者之间提供大量的互动机会。科学会议将包括平台演示、实习生/教师交流午餐和向公众开放的讲座。