Mount Desert Island Stem Cell Symposium

山漠岛干细胞研讨会

• 批准号: 8005471
• 负责人: LEONARD Ira ZON
• 金额: $ 1.1万
• 依托单位: MOUNT DESERT ISLAND BIOLOGICAL LAB
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8005471
• 关键词: 8 year old; Address; Animal Model; Area; Biological; Clinical; Clinical Investigator; Communities; Development; Disease; Epigenetic Process; Faculty; Fishes; General Population; Generations; Genetic Transcription; Human; Invertebrates; Island; Laboratories; Maine; Medical center; Mus; National Institute of General Medical Sciences; Natural regeneration; Nature; Regulation; Research; Research Institute; Research Personnel; Role; Scientific Advances and Accomplishments; Stem Cell Research; Stem cells; Therapeutic; Tissues; Work; Yeasts; Zebrafish; base; comparative; fly; human stem cells; interest; lectures; meetings; mouse model; novel therapeutic intervention; nuclear reprogramming; programs; public health relevance; research study; stem; stem cell biology; stem cell differentiation; stem cell therapy; symposium; tissue regeneration

DESCRIPTION (provided by applicant): The Mount Desert Island Biological Laboratory (MDIBL), The Jackson Laboratory (JAX), and the Maine Medical Center Research Institute (MMCRI) propose to continue the eight-year-old Mount Desert Island Stem Cell Symposium with three annual meetings from 2010 to 2012 with support from the National Institute of General Medical Sciences. The proposed symposia, to be held annually in August 2011, 2012, and 2013 at the Mount Desert Island Biological Laboratory in Salisbury Cove, Maine, will be the 9th, 10th, and 11th Mount Desert Island Stem Cell Symposia since the meeting was established in August 2002. The 2010 Symposium on 'Reprogramming and Epigenetics', will be held August 6 - 7, 2010. The Mount Desert Island Stem Cell Symposium will emphasize epigenetics and nuclear reprogramming in the generation and differentiation of stem cells, and the role of stem and progenitor cells in tissue regeneration. The conference will continue to engage the research strengths of MDIBL, JAX, and MMCRI by emphasizing comparative stem cell research in human, mouse, fish, and invertebrates, a programmatic approach unique to this meeting. The Organizing Committee, comprised of national leaders in biomedical and stem cell research, has developed the program of this symposium to address topical issues important to the stem cell research community. The specific aims of the 2010 symposium are: 1.) Present and discuss research studies of epigenetic regulation of gene transcription and expression in stem cells; 2.) Present and discuss scientific advances in nuclear reprogramming; 3.) Present and discuss research studies of stem cells in tissue development and regeneration; 4.) Present and discuss research in which comparative models (mouse, zebrafish, worm, fly, yeast) are utilized to study epigenetic regulation; and 5.) Provide substantial opportunities for interaction between trainees, investigators new to stem cell research, and investigators well established in these research areas. Scientific sessions will include platform presentations, a trainee/faculty networking lunch, and a lecture open to the general public. PUBLIC HEALTH RELEVANCE: The Mount Desert Island Stem Cell Symposium convenes leading investigators whose work in stem cell biology is focused on a variety of model organisms including human. The comparative nature of the meeting represents the critical need for a broad-based understanding of stem cell biology required to advance the use of human stem cells in new therapeutic approaches to disease. The invited speakers (and the organizing committee) include many clinical investigators interested in therapeutic applications of stem cell research. Their clinical interests keep stem cell therapies at the forefront of the discussion.

描述（由申请人提供）：沙漠山岛生物实验室（MDIBL）、杰克逊实验室（JAX）和缅因州医学中心研究所（MMCRI）建议在国家普通医学科学研究所的支持下，继续举办已有八年历史的沙漠山岛干细胞研讨会，并于2010年至2012年举行三次年会。拟议中的研讨会将于2011年8月、2012年和2013年在缅因州索尔兹伯里湾的荒岛山生物实验室举行，这将是自2002年8月会议成立以来的第9、10和11届荒岛山干细胞研讨会。2010年研讨会上的“重编程和表观遗传学”，将于2010年8月6日至7日举行。沙漠山岛干细胞研讨会将强调干细胞生成和分化中的表观遗传学和核重编程，以及干细胞和祖细胞在组织再生中的作用。会议将继续通过强调人类、小鼠、鱼类和无脊椎动物的比较干细胞研究来发挥MDIBL、JAX和MMCRI的研究优势，这是本次会议独有的一种方案方法。组织委员会由生物医学和干细胞研究领域的国家领导人组成，制定了本次研讨会的计划，以解决对干细胞研究界重要的热点问题。2010年研讨会的具体目标是：（1）介绍并讨论干细胞中基因转录和表达的表观遗传调控研究; 2.）提出并讨论核重编程的科学进展; 3。介绍并讨论干细胞在组织发育和再生中的研究; 4.）目前和讨论的研究中，比较模型（小鼠，斑马鱼，蠕虫，苍蝇，酵母）被用来研究表观遗传调控;和5。为学员、干细胞研究新手和这些研究领域的资深研究者之间的互动提供大量机会。科学会议将包括平台演示，实习生/教师网络午餐，并向公众开放的讲座。 公共卫生相关性：沙漠山岛干细胞研讨会召集领先的研究人员，他们在干细胞生物学方面的工作集中在包括人类在内的各种模式生物上。会议的比较性质表明，迫切需要对干细胞生物学有广泛的了解，以促进在新的疾病治疗方法中使用人类干细胞。受邀演讲者（和组委会）包括许多对干细胞研究的治疗应用感兴趣的临床研究人员。他们的临床兴趣使干细胞疗法处于讨论的最前沿。