2010 FASEB Conference on the Retinoids

2010 年 FASEB 类视黄醇会议

• 批准号: 7911332
• 负责人: NOA NOY
• 金额: $ 4万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7911332
• 关键词: Address; American; Arizona; Biological Process; Biology; Cells; Collaborations; Computer Retrieval of Information on Scientific Projects Database; Databases; Development; Diabetes Mellitus; Discipline; Disease; Embryonic Development; Functional disorder; Funding; Goals; Grant; Health; Homeostasis; Human; Immunity; Immunologist; International; Investigation; Learning; Malignant Neoplasms; Metabolism; Molecular; Nutritional; Obesity; Physiological; Physiology; Postdoctoral Fellow; Regulation; Request for Applications; Research; Research Activity; Research Personnel; Resort; Retinoid Receptor; Retinoids; Role; Scientist; Senior Scientist; Societies; Structural Biologist; Therapeutic; Time; Tretinoin; United States National Institutes of Health; Vision; Vitamin A; Work; career; cell growth regulation; cell type; disorder prevention; graduate student; insight; lectures; meetings; posters; prevent; research and development; skin disorder; stem cell biology; symposium

DESCRIPTION (provided by applicant): This application requests partial support for the 15th Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference on Retinoids to be held at the Carefree Resort in Carefree, Arizona in June 13-18, 2010. This bi-annual research conference has been very well attended (ranging from 125 to 200 attendees over the past 25 years) and remains the sole major national and international conference that addresses the full spectrum of retinoid biology. Our understanding of the mechanisms of action and the biological functions of retinoids has increased rapidly over the last two decades. Nevertheless, there is much that still needs to be learned regarding retinoid actions in both normal human physiology and pathophysiology. To meet this need for information, there is a great deal of ongoing research activity focused on the retinoids (the NIH CRISP database indicates that there are currently 284 funded NIH grants involving retinoid biology). The 2010 conference will consist of a plenary lecture, platform presentations and poster sessions that will allow for the exchange of new research findings amongst scientific attendees. The main topics to be addressed at the conference include: (1) retinoid metabolism and homeostasis; (2) retinoid receptors; (3) enzymatic control of retinoic acid action; (4) retinoids in vision; (5) retinoids in cancer; (6) physiological actions of retinoids; (7) retinoids in development; (8) retinoid regulation of cell growth and differentiation; and (9) retinoid regulation of stem cell biology. The overall goal of the proposed conference on retinoids is to bring together a group of investigators (including senior scientists, mid-career scientists, junior scientists, postdoctoral fellows, and graduate students) who work in diverse disciplines (as biochemists, molecular biologists, nutritional scientists, cancer researchers, developmental biologists, vision researchers, cell biologists, biophysicists, structural biologists, immunologists, chemists, and clinicians) to present and discuss their newest research findings that share a common focus on the retinoids. This conference will provide a forum for the critical review of recent research and for the development of new research ideas and collaborations. This will stimulate new investigations that in time will provide needed insight into the essential actions of retinoids in preventing disease and maintaining health. Narrative Retinoids, the active forms of vitamin A, have wide ranging effects on many aspects of human health including vision, embryonic development, immunity, and differentiation of diverse cell types. Retinoids are important therapeutics for skin disorders and cancer, and they are involved in diabetes/obesity and certain ocular diseases. This bi-annual research conference provides the sole major national and international forum that addresses the full spectrum of retinoid biology. Its goal is to stimulate scientific exchange and new investigations that will provide needed insights into the roles of retinoids in disease prevention and treatment.

描述（由申请人提供）：本申请要求对将于2010年6月13日至18日在亚利桑那州无忧无虑的无忧无虑度假村举行的第15届美国实验生物学学会联合会（FASEB）维甲酸夏季研究会议提供部分支持。这个一年两次的研究会议已经非常好地参加（从125到200与会者在过去的25年），仍然是唯一的主要国家和国际会议，解决类维生素A生物学的全谱。在过去的二十年里，我们对类维生素A的作用机制和生物学功能的理解迅速增加。然而，关于维甲酸在正常人体生理学和病理生理学中的作用，仍有许多需要了解的。为了满足这种信息需求，有大量正在进行的研究活动集中在类维生素A（NIH CRISP数据库显示，目前有284个NIH赠款涉及类维生素A生物学）。2010年会议将包括一个全体演讲，平台介绍和海报会议，将允许科学与会者之间的新的研究成果的交流。会议将讨论的主要议题包括：（1）维甲酸代谢和稳态;（2）维甲酸受体;（3）维甲酸作用的酶控制;（4）维甲酸在视觉中的作用;（5）维甲酸在癌症中的作用;（6）维甲酸的生理作用;（7）维甲酸在发育中的作用;（8）维甲酸对细胞生长和分化的调节;（9）类维生素A对干细胞生物学的调节。拟召开的维甲酸会议的总体目标是召集一组研究人员，（包括高级科学家、职业中期科学家、初级科学家、博士后研究员和研究生）（作为生物化学家，分子生物学家，营养科学家，癌症研究人员，发育生物学家，视觉研究人员，细胞生物学家，生物药理学家，结构生物学家，免疫学家，化学家，和临床医生），介绍和讨论他们的最新研究成果，共同关注维甲酸。本次会议将为最近的研究和新的研究思路和合作的发展提供一个论坛。这将刺激新的研究，及时提供对类维生素A在预防疾病和维持健康方面的基本作用的深入了解。 叙事 类维生素A是维生素A的活性形式，对人类健康的许多方面具有广泛的影响，包括视力，胚胎发育，免疫力和多种细胞类型的分化。类维生素A是皮肤病和癌症的重要治疗剂，并且它们涉及糖尿病/肥胖症和某些眼部疾病。这个一年两次的研究会议提供了唯一的主要国家和国际论坛，解决了维甲酸生物学的全方位。其目标是促进科学交流和新的研究，为类维生素A在疾病预防和治疗中的作用提供必要的见解。