2010 Biointerface Science Gordon Research Conference

2010年生物界面科学戈登研究会议

• 批准号: 7989530
• 负责人: Phillip B Messersmith
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7989530
• 关键词: Adhesions; Behavior; Biocompatible Materials; Biological; Biology; Biophysics; Biosensor; Biotechnology; Cells; Clinical; Dentistry; Development; Diagnostic; Engineering; Genomics; Goals; Healthcare; Interfacial Phenomena; International; Lead; Link; Macromolecular Complexes; Medical; Medicine; Membrane; Membrane Proteins; Microbial Biofilms; Microbiology; Minerals; Modeling; Molecular; Molecular and Cellular Biology; Oral; Play; Proteins; Proteomics; Regenerative Medicine; Request for Applications; Research; Research Design; Research Personnel; Role; Science; Scientist; Surface; Switzerland; System; Technology; biological systems; design; fundamental research; human disease; improved; interest; meetings; physical science; posters; public health relevance; single molecule; symposium; theories

DESCRIPTION (provided by applicant): This application requests partial support for the 2010 Gordon Research Conference on Biointerface Science to be held in Les Diablerets, Switzerland, September 5-10, 2010. The broad and long-term goal of the conference is to enhance our understanding of interactions between biomolecules and surfaces, and the behavior of complex macromolecular systems at materials interfaces, driven by the important role these interactions play in the fields of biology, biotechnology, diagnostics, and medicine. Approximately 160 scientists, engineers and medical scientists will participate, including 22 invited speakers and 9 discussion leaders, whose research interests are related to biointerface science. The specific aims of this meeting are 1) to expose biological scientists and medical researchers to the latest experimental and theoretical findings in the physical sciences and engineering; and 2) to accelerate the rate at which new developments in molecular/cellular biology and biomolecular design, are brought into the domain of physical scientists and engineers. Together, this intellectual interplay will lead new ways in which molecules are designed, studied, and exploited for the vast number of settings in which "biomolecules meet surfaces", including better understanding of interfacial phenomena in biological systems, and for inspiring new treatments and diagnostic strategies for human diseases. The 2010 conference will emphasize molecular-level descriptions of biointerfacial phenomena in nine oral sessions on the following aspects of biointerfaces: Theory, Computation and Modeling of Biointerfaces; Supported Membranes and Membrane Proteins; Interactions of Biomolecules with Crystal/Mineral Surfaces; Single Molecule Biophysics; Mechanochemistry and Biological Adhesion; Microbiology/Biofilms; Biolubrication; Interfaces of Proteins and Cells with Materials; Electrified Biointerfaces. In addition to oral sessions, two poster sessions as well as significant informal interactions will contribute to the goals of the conference. The significance of the application is that this conference has quickly become one of the main international conferences totally devoted to biointerface science, rather than the typical approach of being a small part of a larger conference. The health-relatedness of the application is that this fundamental research will lead to a myriad of new or improved healthcare technologies spanning genomics, proteomics, clinical diagnostics, biosensors, and biomaterials for regenerative medicine and dentistry. PUBLIC HEALTH RELEVANCE: The health-relatedness of the application is linked to enhanced understanding of experimental and theoretical aspects of biointerface science that will lead to a myriad of new or improved healthcare technologies spanning genomics, proteomics, clinical diagnostics, biosensors, and biomaterials for regenerative medicine and dentistry.

描述（由申请人提供）：本申请请求部分支持将于 2010 年 9 月 5 日至 10 日在瑞士莱迪亚布勒雷举行的 2010 年戈登生物界面科学研究会议。该会议的广泛和长期目标是增强我们对生物分子和表面之间的相互作用以及材料界面上复杂大分子系统行为的理解，这些相互作用在生物学、 生物技术、诊断和医学。约160名科学家、工程师和医学家将参加，其中包括22名受邀演讲者和9名讨论负责人，他们的研究兴趣与生物界面科学相关。本次会议的具体目的是1）让生物科学家和医学研究人员了解物理科学和工程领域的最新实验和理论发现； 2) 加快将分子/细胞生物学和生物分子设计的新进展引入物理科学家和工程师领域的速度。总之，这种智力相互作用将引领分子设计、研究和利用的新方式，用于“生物分子与表面相遇”的大量环境，包括更好地理解生物系统中的界面现象，并激发人类疾病的新治疗和诊断策略。 2010年会议将在九个口头会议中强调生物界面现象的分子水平描述，涉及生物界面的以下方面：生物界面的理论、计算和建模；支持膜和膜蛋白；生物分子与晶体/矿物表面的相互作用；单分子生物物理学；机械化学和生物粘附；微生物学/生物膜；生物润滑；蛋白质和细胞与材料的界面；电气化生物界面。除了口头会议之外，两次海报会议以及重要的非正式互动也将有助于实现会议的目标。该应用的意义在于，该会议已迅速成为完全致力于生物界面科学的主要国际会议之一，而不是作为大型会议的一小部分的典型做法。该应用与健康的相关性在于，这项基础研究将带来无数新的或改进的医疗保健技术，涵盖基因组学、蛋白质组学、临床诊断、生物传感器以及再生医学和牙科的生物材料。 公共健康相关性：该应用程序的健康相关性与增强对生物界面科学的实验和理论方面的理解有关，这将带来无数新的或改进的医疗保健技术，涵盖基因组学、蛋白质组学、临床诊断、生物传感器以及再生医学和牙科的生物材料。