Nutritional Epidemiology of Cancer Education and Career Development Program

描述（由申请人提供）：这是寻求R25教育项目癌症营养流行病学资金更新的第二次也是最后一次申请。之前的评审总结总结道：“这是一个非常强大和独特的项目。斯坦普弗博士似乎已经解决了早期申请中提出的大部分问题。这是一个杰出的项目。”最初的提案是在国家信息中心训练处的鼓励和建议下提出的。通过扩大教育和培训项目来推进营养研究是美国国家癌症研究所癌症预防部的首要任务。该计划包括提供持续的领导，专门的教师时间，明确的专业课程，跨学科的研究环境，以及为每个学员提供两个（或更多）导师。这个跨学科的，但重点是，计划是基于营养和流行病学的接口。由Meir Stampfer博士领导，Walter Willett博士担任联合首席研究员，Edward Giovannucci博士担任教育主任，Stephanie Smith-Warner博士担任副教育主任，另外还有Lorelei Mucci博士。最终目标是训练研究人员发现饮食变化可以降低癌症风险和负担的新方法。这个项目现在已经是第六年了（通过免费延期），已经取得了坚实的成就。它利用了哈佛公共卫生学院流行病学和营养系的丰富资源，该学院长期以来一直是公认的流行病学方法、一般癌症流行病学和营养流行病学的教学和实践培训中心。这个教育项目还利用了丹娜-法伯/哈佛癌症中心（DH/HCC）的各种研究机会，这是一个代表哈佛七所附属机构癌症研究的矩阵癌症中心。R25借鉴了饮食和癌症领域的重大进展，例如建立了三个大型队列，包括25万多名男性和女性，在长达28年的时间里反复测量饮食。通过这项培训拨款，我们将现有的各种要素整合在一起，并创造了新的要素，以建立一个连贯的、重点突出的癌症营养流行病学跨学科项目。癌症营养流行病学项目提供了一个独特的利基，同时与其他培训补助金互为补充和协同作用，以便为癌症预防和控制营造一个基于健全生物学的强大环境。这个新项目在吸引优秀候选人方面已经取得了显著的成功。完成课程的学员都在这一领域开始了有前途的职业生涯。

DESCRIPTION (provided by applicant): This is the second and final resubmission to seek renewal of funding for the R25 education program, Nutritional Epidemiology of Cancer. The previous review summary concluded that "This is a very strong and unique program. Dr. Stampfer appears to have addressed most of the problems raised in the earlier application. This is an outstanding program." The original proposal was submitted with the encouragement and advice of the NCI Training Branch. Advancing nutrition research through expanded education and training programs is a high priority of the Division of Cancer Prevention at the National Cancer Institute. This program includes provision of sustained leadership, dedicated faculty time, a well-defined specialized curriculum, interdisciplinary research environments, and two (or more) mentors for each trainee. This interdisciplinary, yet focused, program is based on the interface of nutrition and epidemiology. It is led by Dr. Meir Stampfer, with Dr. Walter Willett as co-Principal Investigator, Dr. Edward Giovannucci as Education Director and Dr. Stephanie Smith-Warner as Associate Education Director, and addition of Dr. Lorelei Mucci. The ultimate goal is to train researchers to discover new ways in which changes in diet can reduce the risk and burden of cancer. The program, now in its sixth year (through a no-cost extension), already has established a solid record of achievement. It has drawn on the wealth of other resources from the Departments of Epidemiology and Nutrition at the Harvard School of Public Health, which has long been a recognized center for didactic and practical training in epidemiologic methods, cancer epidemiology in general, and nutritional epidemiology. This educational program also draws on diverse research opportunities within the Dana-Farber/Harvard Cancer Center (DH/HCC), a matrix cancer center representing cancer research across seven Harvard-affiliated institutions. The R25 draws upon major developments in the area of diet and cancer such as the creation of three large cohorts comprising over 250,000 men and women followed for as long as 28 years with repeated measures of diet. Through this training grant, we have brought together the various elements already in place, and created new elements to build a coherent and focused interdisciplinary program in the nutritional epidemiology of cancer. The Nutritional Epidemiology of Cancer program provides a unique niche, while being complementary and synergistic with the other training grants in order to foster a strong environment, based on sound biology, for cancer prevention and control. This new program has already demonstrated remarkable success in attracting outstanding candidates. Trainees who have completed the program have uniformly embarked on promising careers in this area.