Administrative Core

行政核心

• 批准号: 7797881
• 负责人: F PETER Guengerich
• 金额: $ 42.3万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-04 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7797881
• 关键词: Accounting; Applications Grants; Basic Science; Center Core Grants; Department of Defense; Environmental Health; Funding; Goals; Health; Human; Laboratories; Manganese; Medical Students; Mentored Clinical Scientist Development Program; Mercury; Molecular Toxicology; National Institute of Environmental Health Sciences; Predisposition; Research; Research Training; Resources; Strategic Planning; Superfund; Toxic effect; Training Programs; Training and Infrastructure; career development; drug mechanism; environmental toxicology; medical schools; operation; patient oriented; programs; ranpirnase

The Administrative Core is responsible for coordinating P30 EHS Core Center activities, including the integration of all Center components, management of day-to-day operations, program assessment, and various clerical and accounting functions. The Center in Molecular Toxicology has recently expanded into a more comprehensive organization that administers several units under a common "umbrella," as part of the new 5-year strategic plan distributed in 2006 by Vanderbilt's Associate Vice-Chancellor for Research (and current Dean of the School of Medicine), Dr J. Balser. Historically, the Center consisted of two major programs: the P30 EHS Core Center grant (this application, P30 ES000267) and the affiliated training program in environmental toxicology (T32 ES007028). Today the P30 EHS Core Center and training programs continue to provide much of the research and training infrastructure for the Center in Molecular Toxicology, but several other programs and initiatives are now included under the Center's administrative umbrella: ¿ Advanced Research Cooperation in Environmental Health (ARCH) with Meharry Medical College (S11 ES014156) Manganese Health Research Program (funded by the Department of Defense) ¿ Patient-Oriented Career Development Program (K12 ES015855), which provides support for environmental health science scholars (described in further detail, pp. 146-151) ¿ A newly funded NIEHS T35 short-term summer research and training program for medical students (T35 ES016534-01) ¿ An NIEHS Superfund Basic Research Program with Oak Ridge National Laboratory focusing on mechanisms of susceptibility to mercury toxicity (submitted 04/08). The priority score from this round was not competitive for funding, and a resubmission is planned for 04/10. ¿ A proposed institutionally-sponsored program in mechanisms of drug-induced cellular toxicity Thus the Administrative Core has been instrumental in leveraging resources with the goal of amplifying Vanderbilt's presence in the field of environmental toxicology as it relates to human health.

行政核心负责协调P30 EHS核心中心的活动，包括所有中心组成部分的整合、日常运营管理、计划评估以及各种文书和会计职能。该中心在分子毒理学最近已扩大到一个更全面的组织，管理几个单位下一个共同的“保护伞”，作为新的5年战略计划的一部分，分布在2006年由范德比尔特的副校长研究（和医学院的现任院长），博士J。从历史上看，该中心包括两个主要项目：P30 EHS核心中心拨款（本申请，P30 ES 000267）和附属的环境毒理学培训项目（T32 ES 007028）。今天，P30 EHS核心中心和培训计划继续为分子毒理学中心提供大部分研究和培训基础设施，但其他几个计划和举措现在已纳入该中心的行政保护伞： 环境健康高级研究合作（环境）与Meharry医学院（S11 ES 014156）锰健康研究计划（由国防部资助） 以病人为导向的职业发展计划（K12 ES 015855），为环境健康科学学者提供支持（详细描述，第100页）。（第146-151段） 新资助的NIEHS T35短期暑期医学生研究和培训计划（T35 ES 016534 -01） 橡树岭国家实验室的NIEHS超级基金基础研究方案，重点是对汞毒性敏感性的机制（2008年4月提交）。这一轮的优先分数对资金没有竞争力，计划于2010年4月重新提交。 一个拟议的机构赞助的计划在药物诱导的细胞毒性机制 因此，行政核心一直在利用资源，扩大范德比尔特的存在，在环境毒理学领域的目标，因为它涉及到人类健康的工具。