PHYTOSTEROL GLYCOSIDES REDUCE CHOLESTEROL ABSORPTION IN HUMANS

植物甾醇糖苷减少人体胆固醇吸收

• 批准号: 8168812
• 负责人: XI LIN
• 金额: $ 1.13万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-10 至 2010-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8168812
• 关键词: Biological; Cholesterol; Computer Retrieval of Information on Scientific Projects Database; Equilibrium; Excretory function; Food; Funding; Glycosides; Grant; Human; Institution; Intestines; Phytosterols; Research; Research Personnel; Resources; Source; Testing; United States National Institutes of Health; cholesterol absorption

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Dietary phytosterols inhibit intestinal cholesterol absorption and regulate whole body cholesterol excretion and balance. However, they are biochemically heterogeneous and a portion is glycosylated in some foods with unknown effects on biological activity. We tested the hypothesis that phytosterol glycosides reduce cholesterol absorption in humans.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 膳食植物甾醇抑制肠道胆固醇吸收，调节全身胆固醇排泄和平衡。然而，它们在生物化学上是异质的，并且在某些食物中有一部分被糖基化，对生物活性的影响未知。我们测试了植物甾醇糖苷减少人体胆固醇吸收的假设。