Oral human papillomavirus infection in head and neck cancers and the general population.

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Mucosal cancers of the head and neck are the sixth most common type of cancer worldwide and are increasing in Australia. Human papillomaviruses (HPV), which are the major cause of cervical cancer and the cause of 5% of all human cancers, have recently also been implicated as a cause of some types of head and neck cancer, especially in patients younger than 50 years. In this project we will investigate how HPV infection regulates the expression of key genes in cancers of the head and neck, and how that affects prognosis of this disease.