Side effects of Cancer Therapy: Chemobrain: Mechanisms & Assessments

癌症治疗的副作用：Chemobrain：机制

• 批准号: 8203674
• 负责人: DARET K ST CLAIR
• 金额: $ 2万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8203674
• 关键词: Adverse effects; Area; Attention; Brain; Cancer Center; Cancer Patient; Cancer Survivor; Chemotherapy-Oncologic Procedure; Clinical; Clinical Oncology; Cognition; Collaborations; Communities; Data; Development; Diagnosis; Disease; Funding; Goals; Health Professional; Healthcare; Injury; International; Intervention; Kentucky; Knowledge; Life; Memory; Methodology; Minority; National Cancer Institute; Neurologic; Neuronal Injury; Normal tissue morphology; Nurses; Patients; Pharmaceutical Preparations; Physicians; Preventive; Publishing; Quality of life; Research; SEER Program; Scientist; Societies; Survivors; Therapeutic; Tissues; Training; Translations; Universities; Woman; anticancer research; base; cancer therapy; chemobrain; chemotherapeutic agent; clinical practice; experience; improved; meetings; member; novel strategies; prevent; success; symposium

DESCRIPTION (provided by applicant): Cancer therapy-induced injury to normal tissue is a major side effect experienced by cancer patients and is, unfortunately, an understudied area. The number of cancer survivors now exceeds 11 million in the US alone and the total number of survivors worldwide is constantly increasing. The University of Kentucky Markey Cancer Center Conference on the Side Effects of Cancer Therapy:Chemobrain: Mechanisms & Assessments will be held in Lexington, Kentucky, during October 12-14, 2011, and will include an opening session with cancer survivors. Two prominent scientists in the area of cognition and memory, Larry Squire from UCSD and James McGaugh from UC Irvine, have agreed to be keynote speakers. The conference is sponsored by the Markey Cancer Center and is an international symposium bringing together a community of scientists, physicians, nurses, health care professionals, physicians and scientists-in-training in the area of clinical oncology. The objectives of the meeting are to coordinate, exchange, and disseminate information and to explore potential intervention. The focus will be the mechanisms of neuronal injury resulting from anticancer chemotherapeutic agents not directly targeting the brain, strategies for assessments, intervention strategies, and possible translation from basic studies into clinical practice. PUBLIC HEALTH RELEVANCE: Cancer therapy-induced normal tissue injury is a major side effect experienced by cancer patients and is an understudied area. The number of cancer survivors now exceeds 11 million in the US alone. As such, the need to provide health care that supports a high quality of life after cancer treatment has become a new health care challenge, and injury to noncancerous tissue is in need of special attention. The University of Kentucky Markey Cancer Center Conference on Side Effects of Cancer Therapy: Chemobrain: Mechanisms & Assessments is a very timely and important topic for the benefit of patients. The conference will be held in Lexington, Kentucky during October 12-14, 2011, and will include an opening session with cancer survivors. The conference is an international symposium bringing together a community of clinicians and scientists in the area of cancer research and chemotherapy. The goals of the conference are to coordinate, exchange, and disseminate information and to explore novel strategies to diagnose and to prevent or minimize the neurological problems associated with chemotherapeutic drugs not directly targeting the brain.

描述（由申请人提供）：癌症治疗引起的正常组织损伤是癌症患者经历的主要副作用，不幸的是，这是一个研究不足的领域。仅在美国，癌症幸存者的数量就超过了1100万，全球幸存者的总数还在不断增加。肯塔基州大学马基癌症中心关于癌症治疗副作用的会议：Chemobrain：机制与评估将于2011年10月12日至14日在肯塔基州列克星敦举行，并将包括与癌症幸存者的开幕式。认知和记忆领域的两位杰出科学家，来自UCSD的Larry Squire和来自UC Irvine的James McGaugh，已同意担任主题演讲人。该会议由Markey癌症中心主办，是一个国际研讨会，汇集了临床肿瘤学领域的科学家，医生，护士，医疗保健专业人员，医生和科学家的培训社区。会议的目标是协调、交流和传播信息，并探讨可能的干预措施。重点将是神经元损伤的机制，抗癌化疗药物不直接针对大脑，评估策略，干预策略，并可能从基础研究转化为临床实践。 公共卫生关系：癌症治疗引起的正常组织损伤是癌症患者经历的主要副作用，并且是一个未充分研究的领域。仅在美国，癌症幸存者的数量就超过了1100万。因此，在癌症治疗后提供支持高质量生活的医疗保健的需求已经成为新的医疗保健挑战，并且对非癌组织的损伤需要特别关注。肯塔基州大学马基癌症中心关于癌症治疗副作用的会议：化学疗法：机制与评估是一个非常及时和重要的主题，有利于患者。会议将于2011年10月12日至14日在肯塔基州的列克星敦举行，并将包括与癌症幸存者的开幕式。该会议是一个国际研讨会，汇集了癌症研究和化疗领域的临床医生和科学家。会议的目标是协调，交流和传播信息，并探索新的策略来诊断和预防或最大限度地减少与不直接靶向大脑的化疗药物相关的神经系统问题。