Infection, Inflammation, Immunity

感染、炎症、免疫

• 批准号: 8205421
• 负责人: Andrea Joan Tenner
• 金额: $ 0.3万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-15 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8205421
• 关键词: Academia; Address; Area; Awareness; Basic Science; Biology; Cities; Clinical; Collaborations; Communicable Diseases; Dental crowns; Disabled Persons; Disease; Environment; Epigenetic Process; Fostering; Funding; Goals; Immune response; Immune system; Immunity; Industry; Infection; Inflammation; Inflammatory; Injury; Kansas; Laboratories; Leukocytes; Lipids; Location; Manufacturer Name; Mental disorders; Minority; Minority Groups; Molecular; Natural Immunity; Nervous system structure; Oral; Participant; Pathogenesis; Pathway interactions; Population; Productivity; Reagent; Regulation; Request for Proposals; Research; Research Personnel; Scientific Advances and Accomplishments; Scientific Societies; Scientist; Signal Transduction; Societies; Solutions; Translational Research; Trauma; Underrepresented Minority; Woman; Work; abstracting; immune activation; innovation; insight; macrophage; meetings; member; monocyte; neuroinflammation; novel; pathogen; posters; programs; response; success; symposium; technology development

DESCRIPTION (provided by applicant): The annual meeting of Society for Leukocyte Biology, a leading scientific society addressing immune activation by infection or injury and the organization and control of that response, has a tradition of highlighting the most innovative and timely work on the mechanisms underlying host-pathogen interactions, dysregulation as a result of trauma or injury and leukocyte functions in the pathogenesis of disease. The 2011 meeting "Infection, Inflammation and Immunity" will continue this tradition by bringing together scientific researchers of all levels in an environment geared to maximize interactions and the exchange of ideas. Objective 1. To provide a forum for approximately 300-350 participants from academic, governmental, and industrial laboratories worldwide to share the latest most significant advances and new discoveries in inflammation and immunity, with an added focus on the impact of the immune system in the nervous system. The program will feature presentations by invited leaders in the field, as well as talks and poster presentations by junior investigators and trainees chosen from among the submitted abstracts from laboratories worldwide. These areas include the molecular pathways involved in inflammation and infection, the accelerating field of neuroinflammation, emerging importance of lipids in activation, signaling, and effector functions, epigenetic regulation of inflammation and Immunity, the paradigm shifting discoveries of monocyte subsets and the growing awareness of the extent of plasticity in the innate immune response afforded by malleable macrophage, the extent of interaction and cross regulation between the innate and adaptive immune response and the influence of the vasculature on the immune system (and vs versa). Objective 2. To present a program that captures significant newly emerging areas in which the immune systems contributes significant influence over proper function, and thus provides potential targets for therapies. A pre-meeting Satellite Symposium on "The Immune System in Psychiatric Disorders" (separate organization and funding) will provide attendees with insight into this rapidly emerging area, in addition to a complementary meeting plenary session on Neuroinflammation. Objective 3. To provide an opportunity for young investigators and trainees to interact closely with well- established researchers in their fields both formally and informally and to present their research in both poster and podium sessions. Objective 4. To provide an opportunity for women, members of under-represented minority groups, and persons with disabilities to participate in a meeting that showcases their work and facilitates one on one interactions with other scientists in their fields, as well as providing a forum to address obstacles and explore solutions that will optimize their success. PUBLIC HEALTH RELEVANCE: The scientific advances in the complementary and interactive fields of inflammation, innate immunity, infectious disease and inflammatory disorders continues to accelerate, with increased emphasis and the development of technology. The annual conference of the Society for Leukocyte Biology with a guest session sponsored by The Inflammation Research Association and a satellite Symposium provided by the Psychoimmunolgy Research Society in 2011 will provide a much needed opportunity for a highly productive exchange of scientific information on the latest advances and best work in these fields, which have enormous relevance to a broad range of clinical disorders currently prevalent in the US and worldwide populations. Moreover, the conference will strongly promote effective interactions among scientists from different fields, between established and developing junior investigators, and with women and minority scientists with the hope of developing productive collaborations and/or accelerating productivity and success.

描述(由申请者提供)：白细胞生物学学会年会是一家领先的科学学会，致力于研究感染或损伤引起的免疫激活以及这种反应的组织和控制，传统上强调在宿主-病原体相互作用、创伤或损伤引起的调节失调以及疾病发病机制中的白细胞功能方面最具创新性和最及时的工作。2011年的“感染、炎症和免疫”会议将延续这一传统，将所有级别的科学研究人员聚集在一个旨在最大限度地进行互动和思想交流的环境中。目标1.为来自世界各地的学术、政府和工业实验室的大约300-350名参与者提供一个论坛，分享炎症和免疫方面的最新重大进展和新发现，并特别关注免疫系统在神经系统中的影响。该计划将包括该领域特邀领导人的演讲，以及从世界各地实验室提交的摘要中挑选出来的初级调查人员和受训人员的演讲和海报演示。这些领域包括参与炎症和感染的分子途径，神经炎症的加速领域，脂类在激活、信号和效应功能中的新出现的重要性，炎症和免疫的表观遗传调节，单核细胞亚群的范式转变的发现，对可塑巨噬细胞提供的先天性免疫反应的可塑性程度的日益认识，天然和获得性免疫反应之间的相互作用和交叉调节的程度，以及血管系统对免疫系统的影响(反之亦然)。目的2.提出一个计划，该计划捕捉到免疫系统对正常功能有重大影响的重要新兴领域，从而为治疗提供潜在的靶点。会议前举行的关于“精神疾病中的免疫系统”的卫星研讨会(单独的组织和资金)将为与会者提供对这一迅速崛起的领域的洞察，此外还将举行关于神经炎症的补充会议全体会议。目标3.为年轻的研究人员和受训人员提供机会，与他们所在领域的知名研究人员进行正式和非正式的密切互动，并在海报和讲台上介绍他们的研究成果。目标4.为妇女、代表性不足的少数群体成员和残疾人提供机会，参加一次会议，展示她们的工作，促进与各自领域的其他科学家一对一的互动，并提供一个论坛，以克服障碍，探索解决办法，使他们取得最大的成功。 与公共卫生的相关性：炎症、先天免疫、传染病和炎症性疾病等互补和互动领域的科学进步继续加速，并日益受到重视和技术的发展。由炎症研究协会主办的年度会议和2011年由心理免疫研究学会提供的卫星研讨会将提供一个非常必要的机会，就这些领域的最新进展和最佳工作进行高效的科学信息交流，这些领域与目前在美国和世界各地流行的广泛的临床疾病具有巨大的相关性。此外，会议将大力促进来自不同领域的科学家之间的有效互动，现有和发展中的初级调查人员之间的有效互动，以及与妇女和少数族裔科学家的有效互动，以期开展富有成效的合作和(或)加速生产力和成功。