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中文摘要
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描述(由申请人提供):白细胞生物学学会年会是一个领先的科学学会,致力于解决感染或损伤引起的免疫激活以及该反应的组织和控制,其传统是突出宿主-病原体相互作用机制、创伤或损伤导致的失调以及疾病发病机制中白细胞功能的最具创新性和及时性的工作。2011年“感染、炎症和免疫”会议将继续这一传统,将各级科学研究人员聚集在一个最大限度地开展互动和交流思想的环境中。 目的1.为来自全球学术,政府和工业实验室的约300-350名参与者提供论坛,分享炎症和免疫方面的最新最重要进展和新发现,并重点关注免疫系统对神经系统的影响。该计划将包括该领域受邀领导人的演讲,以及从全球实验室提交的摘要中选出的初级研究人员和学员的演讲和海报演示。这些领域包括参与炎症和感染的分子途径,神经炎症的加速领域,脂质在活化,信号传导和效应器功能中的重要性,炎症和免疫的表观遗传调节,单核细胞亚群的范式转变发现以及对可塑性巨噬细胞提供的先天免疫应答中可塑性程度的日益认识,先天性和适应性免疫应答之间的相互作用和交叉调节的程度以及脉管系统对免疫系统的影响(反之亦然)。 目标2.提出一个程序,捕捉重要的新出现的领域,其中免疫系统对正常功能产生重大影响,从而为治疗提供潜在的目标。一个关于“精神疾病中的免疫系统”的会前卫星研讨会(单独的组织和资金)将为与会者提供对这个迅速崛起的领域的深入了解,此外还有一个关于神经炎症的补充会议全体会议。 目标3.为年轻的调查人员和受训人员提供机会,使他们能够正式和非正式地与各自领域的知名研究人员密切互动,并在海报和讲台上展示他们的研究成果。 目标4.为妇女、代表性不足的少数群体成员和残疾人提供一个机会,让他们参加一个会议,展示他们的工作,促进与各自领域的其他科学家一对一的互动,并提供一个论坛,解决障碍,探索将使他们取得最大成功的解决方案。 公共卫生相关性:炎症、先天免疫、传染病和炎症性疾病等互补和互动领域的科学进步继续加速,技术的发展和重视程度不断提高。2011年,白细胞生物学学会年会由炎症研究协会主办,并由心理免疫学研究协会提供卫星研讨会,这将为这些领域的最新进展和最佳工作提供一个非常有成效的科学信息交流机会。其与目前在美国和全世界人群中流行的广泛的临床病症具有巨大的相关性。此外,会议将大力促进来自不同领域的科学家之间的有效互动,建立和发展初级研究人员之间的有效互动,以及与妇女和少数民族科学家的有效互动,以期发展富有成效的合作和/或加速生产力和成功。
英文摘要
DESCRIPTION (provided by applicant): The annual meeting of Society for Leukocyte Biology, a leading scientific society addressing immune activation by infection or injury and the organization and control of that response, has a tradition of highlighting the most innovative and timely work on the mechanisms underlying host-pathogen interactions, dysregulation as a result of trauma or injury and leukocyte functions in the pathogenesis of disease. The 2011 meeting "Infection, Inflammation and Immunity" will continue this tradition by bringing together scientific researchers of all levels in an environment geared to maximize interactions and the exchange of ideas. Objective 1. To provide a forum for approximately 300-350 participants from academic, governmental, and industrial laboratories worldwide to share the latest most significant advances and new discoveries in inflammation and immunity, with an added focus on the impact of the immune system in the nervous system. The program will feature presentations by invited leaders in the field, as well as talks and poster presentations by junior investigators and trainees chosen from among the submitted abstracts from laboratories worldwide. These areas include the molecular pathways involved in inflammation and infection, the accelerating field of neuroinflammation, emerging importance of lipids in activation, signaling, and effector functions, epigenetic regulation of inflammation and Immunity, the paradigm shifting discoveries of monocyte subsets and the growing awareness of the extent of plasticity in the innate immune response afforded by malleable macrophage, the extent of interaction and cross regulation between the innate and adaptive immune response and the influence of the vasculature on the immune system (and vs versa). Objective 2. To present a program that captures significant newly emerging areas in which the immune systems contributes significant influence over proper function, and thus provides potential targets for therapies. A pre-meeting Satellite Symposium on "The Immune System in Psychiatric Disorders" (separate organization and funding) will provide attendees with insight into this rapidly emerging area, in addition to a complementary meeting plenary session on Neuroinflammation. Objective 3. To provide an opportunity for young investigators and trainees to interact closely with well- established researchers in their fields both formally and informally and to present their research in both poster and podium sessions. Objective 4. To provide an opportunity for women, members of under-represented minority groups, and persons with disabilities to participate in a meeting that showcases their work and facilitates one on one interactions with other scientists in their fields, as well as providing a forum to address obstacles and explore solutions that will optimize their success. PUBLIC HEALTH RELEVANCE: The scientific advances in the complementary and interactive fields of inflammation, innate immunity, infectious disease and inflammatory disorders continues to accelerate, with increased emphasis and the development of technology. The annual conference of the Society for Leukocyte Biology with a guest session sponsored by The Inflammation Research Association and a satellite Symposium provided by the Psychoimmunolgy Research Society in 2011 will provide a much needed opportunity for a highly productive exchange of scientific information on the latest advances and best work in these fields, which have enormous relevance to a broad range of clinical disorders currently prevalent in the US and worldwide populations. Moreover, the conference will strongly promote effective interactions among scientists from different fields, between established and developing junior investigators, and with women and minority scientists with the hope of developing productive collaborations and/or accelerating productivity and success.
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Assessing cell specific proteomes in the presence and absence of C5a complement signaling in Alzheimer's disease models
  • 批准号:
    10223186
  • 项目类别:
  • 资助金额:
    $18.87万
  • 财政年份:
    2020
  • 负责人:
    Andrea Joan Tenner
  • 依托单位:
Inflammation in Innate and Adaptive Immune Mechanisms
  • 批准号:
    8400393
  • 项目类别:
  • 资助金额:
    $0.62万
  • 财政年份:
    2012
  • 负责人:
    Andrea Joan Tenner
  • 依托单位:
Interaction of Clq on Phagocytic Cells
  • 批准号:
    7846569
  • 项目类别:
  • 资助金额:
    $5.0万
  • 财政年份:
    2009
  • 负责人:
    Andrea Joan Tenner
  • 依托单位:
Complement and Inflammation in Pathogenesis of Dementia
  • 批准号:
    6587294
  • 项目类别:
  • 资助金额:
    $22.86万
  • 财政年份:
    2002
  • 负责人:
    Andrea Joan Tenner
  • 依托单位:
海外基金