The First International Symposium on IgG4-Related Systemic Disease

描述（由申请人提供）：我们计划组织和举办世界上第一次IgG4相关全身性疾病（IgG4- rsd）国际研讨会。我们已获得世界主要研究人员的承诺，参加这次研讨会。我们的组委会的专业知识涵盖了当前关于IgG4-RSD的所有知识，包括来自医学，外科，病理学和放射学的至少十几个亚专业的专业知识，其中包括风湿病学，免疫学，过敏学，胃肠病学，胃肠病理学，血管病理学，头颈病理学，横断面成像（放射学）和肝胆外科。我们制定了一项议程，以解决当今该领域研究人员和临床医生面临的主要问题，从围绕疾病发病机制的许多未知因素到疾病的临床谱。该议程还将涵盖诊断标准、疾病活动指数的制定、关于标准治疗方法的共识讨论以及新治疗方法。我们期待从研讨会中出现几个新的方向，包括结果测量的验证研究，跨器官系统疾病病理标准的更直接的讨论，数据和样本共享的计划，以及临床试验的发展。在有可能出现新的治疗方法和病理生理学新见解的时候，拟议的研讨会将对全球IgG4-RSD研究者产生激励作用。

DESCRIPTION (provided by applicant): We plan to organize and conduct the world's first international symposium on IgG4- related systemic disease (IgG4-RSD). We have secured commitments from the world's major researchers to participate in this Symposium. The expertise of our Organizing Committees spans the full spectrum of current knowledge about IgG4-RSD, and includes expertise from at least a dozen subspecialties within medicine, surgery, pathology, and radiology, among which are Rheumatology, Immunology, Allergy, Gastroenterology, Gastrointestinal Pathology, Vascular Pathology, Head & Neck Pathology, cross-sectional imaging (Radiology), and Hepatobiliary Surgery. We have developed an agenda that addresses the major questions confronting researchers and clinicians in the field today, from the many unknowns surrounding disease pathogenesis to the clinical spectrum of disease. The agenda will also cover diagnostic criteria, the development of disease activity indices, consensus discussions on standard approaches to therapy, and novel treatments. We anticipate several new directions emerging from the Symposium, including validation studies for outcome measures, more directed discussions about pathologic criteria for the disease across organ systems, plans for data and sample sharing, and the development of clinical trials. The proposed Symposium will have a galvanizing effect on the world's IgG4-RSD investigators at a time when the possibility of novel treatment approaches and new insights into pathophysiology exist.