2011 Cartilage Biology & Pathology GRC

2011年软骨生物学

• 批准号: 8119807
• 负责人: Karen M. Lyons
• 金额: $ 2.1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-01 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8119807
• 关键词: Academia; Address; Adult; Aging; Biochemistry; Biology; Biomechanics; Birth; Bone Marrow; Bone Tissue; Cartilage; Cartilage Diseases; Cellular biology; Cessation of life; Chemicals; Childhood; Clinic; Clinical; Collaborations; Complex; Data; Degenerative Disorder; Degenerative polyarthritis; Development; Developmental Biology; Diagnosis; Discipline; Disease; Engineering; Environmental Risk Factor; Europe; Event; Extracellular Matrix; Fostering; Friction; Future; Genes; Genetic; Goals; Government; Growth; In Vitro; Industry; Interdisciplinary Study; Intervertebral disc structure; Investigation; Joints; Knowledge; Life; Maintenance; Mediating; Mentors; Modeling; Molecular Biology; Natural regeneration; Occupational; Orthopedics; Pain; Participant; Pathology; Population; Postdoctoral Fellow; Prevalence; Prevention; Public Health; Replacement Arthroplasty; Research; Research Personnel; Rheumatoid Arthritis; Risk; Scientist; Senior Scientist; Series; Shock; Signal Pathway; Site; Skeleton; Source; Stem cells; Surface; Time; Tissue Engineering; Tissues; Vertebral column; arthropathies; bone; cellular engineering; congenital skeletal disorder; effective therapy; graduate student; improved; in vivo; insight; interdisciplinary collaboration; interest; intervertebral disk degeneration; meetings; novel; planetary Atmosphere; posters; programs; repaired; success; symposium; synthetic biology; treatment strategy; vertebra body

DESCRIPTION (provided by applicant): This is a request for support for the fifth meeting in a highly successful series of Gordon Research Conferences on Cartilage Biology and Pathology, to be held at the Ventura Beach Marriott, Ventura Beach, Ca, March -11, 2011. Building on the success of the previous conferences, the meeting brings together outstanding senior and junior scientists, including advanced graduate students and postdoctoral fellows, for a 4.5 day program of formal presentations, poster sessions, and informal discussions. The participants share an interest in cartilage biology and pathology, but represent a broad range of disciplines, including developmental biology, extracellular matrix biochemistry, cell and molecular biology, tissue engineering, pathology, genetics, synthetic biology, and orthopaedics. When cartilage fails, the consequences can be severe, ranging from death near the time of birth to reduced growth of the skeleton during childhood, or degenerative joint and intervertebral disc disease in adults. The prevalence of adult diseases of cartilage is increasing in the aging US population. Great strides have been made in the identification of genes that control cartilage formation, and loci that predispose to degenerative disease. At the same time, stem cell and tissue engineering studies are increasing the potential options for repair and regeneration of damaged cartilage. However, much remains to be understood before this knowledge can be employed in the clinic. This meeting will address where we stand today with respect to therapy for cartilage, and what developments are in the pipeline. This is the ONLY meeting that brings together researchers spanning the broad spectrum of cartilage biology in an informal setting where it is possible to interact extensively. The conference is held every other year, alternating between a site in Europe and a site in the US, maximizing opportunities for interactions with colleagues around the world. The meeting is distinctive in its ability to provide junior scientists, postdoctoral fellows, and advanced graduate students extensive access to senior scientists, enabling mentoring, networking, and establishment of collaborations. The conference has consistently been rated as "outstanding" by the participants. The format remains unchanged from our previous highly successful conferences, with ample time for informal discussions.

描述（由申请人提供）：这是一个支持的请求，在一个非常成功的系列戈登研究会议的第五次会议上的Carpendum生物学和病理学，将在文图拉海滩万豪酒店，文图拉海滩，加利福尼亚州，2011年3月-11日举行。在以往会议成功的基础上，会议汇集了优秀的高级和初级科学家，包括高级研究生和博士后研究员，进行为期4.5天的正式演讲，海报会议和非正式讨论。参与者对软骨生物学和病理学感兴趣，但代表了广泛的学科，包括发育生物学，细胞外基质生物化学，细胞和分子生物学，组织工程，病理学，遗传学，合成生物学和骨科。当软骨失败时，后果可能是严重的，从出生时的死亡到儿童时期骨骼生长减少，或成年人的退行性关节和椎间盘疾病。成人软骨疾病的患病率在老龄化的美国人口中正在增加。在识别控制软骨形成的基因和易患退行性疾病的基因位点方面已经取得了很大进展。与此同时，干细胞和组织工程研究正在增加受损软骨修复和再生的潜在选择。然而，在这些知识可以应用于临床之前，还有很多事情需要了解。本次会议将讨论我们今天在软骨治疗方面的立场，以及正在进行的发展。这是唯一的会议，汇集了研究人员跨越广泛的软骨生物学在一个非正式的设置，它是可能的广泛互动。会议每隔一年举行一次，在欧洲和美国的一个地点之间交替举行，最大限度地增加与世界各地同事互动的机会。该会议的独特之处在于它能够为初级科学家，博士后研究员和高级研究生提供与高级科学家广泛接触的机会，从而能够进行指导，建立网络和建立合作。会议一直被与会者评为“杰出”。与我们以前非常成功的会议相比，会议的形式保持不变，有充足的时间进行非正式讨论。